https://www.forbes.com/sites/williamhaseltine/2021/05/18/a-third-sars-cov-2-variant-of-interest-potentially-concern-emerges-from-sub-saharan-africa/?sh=46b2904c5e20 A Third SARS-CoV-2 Variant Of Interest (Potentially Concern) Emerges From Sub-Saharan Africa As Dudas et al. suggest in their analysis of the B.1.620 variant, despite the variant first being detected in Europe, flight records and patient data suggest that it likely emerged in the Central African Republic and Cameroon. As passengers traveled between these African countries and European nations like Lithuania, Germany, and France, the variant created a foothold and spread in Europe. This reinforces the probable origin of the B.1.620 variant in Central Africa and the global nature of this pandemic. Covid-19 disease anywhere is of grave concern for everyone. As of yet, there are only 278 sequences of B.1.620 in the GISAID virus database, but there are likely many more cases throughout Europe and Africa. At the time of writing, Lithuania is within the top eight of rates of confirmed Covid-19 cases per day, according to the New York Times coronavirus tracker. The B.1.620 variant may be a force behind their high case rate due to its mutations. The origin of a new variant of interest from Cameroon points to the need for continued global surveillance in Africa, which, up until now, has been notably absent with the exception of South Africa. Given what is happening in other parts of the world, such as India and Brazil, this is a continent we should be paying close attention to for emerging variants. In recent weeks, another variant was identified out of Tanzania in an Angolan airport, which carries a similar wealth of dangerous mutations from an entirely separate lineage. As the virus continues to spread around the world, new variants will only continue to appear, which will be a challenge for detection, mitigation, therapeutic treatment and prevention, and vaccines. 有人说这个中非新毒株比印度毒株更强。 因为数据还不多，没看到疫苗是否对此变种有效的研究。
A Third SARS-CoV-2 Variant Of Interest (Potentially Concern) Emerges From Sub-Saharan Africa
As Dudas et al. suggest in their analysis of the B.1.620 variant, despite the variant first being detected in Europe, flight records and patient data suggest that it likely emerged in the Central African Republic and Cameroon. As passengers traveled between these African countries and European nations like Lithuania, Germany, and France, the variant created a foothold and spread in Europe. This reinforces the probable origin of the B.1.620 variant in Central Africa and the global nature of this pandemic. Covid-19 disease anywhere is of grave concern for everyone.
As of yet, there are only 278 sequences of B.1.620 in the GISAID virus database, but there are likely many more cases throughout Europe and Africa. At the time of writing, Lithuania is within the top eight of rates of confirmed Covid-19 cases per day, according to the New York Times coronavirus tracker. The B.1.620 variant may be a force behind their high case rate due to its mutations.
The origin of a new variant of interest from Cameroon points to the need for continued global surveillance in Africa, which, up until now, has been notably absent with the exception of South Africa. Given what is happening in other parts of the world, such as India and Brazil, this is a continent we should be paying close attention to for emerging variants. In recent weeks, another variant was identified out of Tanzania in an Angolan airport, which carries a similar wealth of dangerous mutations from an entirely separate lineage. As the virus continues to spread around the world, new variants will only continue to appear, which will be a challenge for detection, mitigation, therapeutic treatment and prevention, and vaccines.
有人说这个中非新毒株比印度毒株更强。 因为数据还不多，没看到疫苗是否对此变种有效的研究。
欧洲发现新冠新病毒株，毒力远超印度“三重变异株”
19个突变，2个能免疫逃逸的变异点
随着印度疫情震慑全球，印度的三重变异毒株声名远播，让人觉得蛊王已经诞生。然而，B.1.620——一种包含许多重点突变的19重变异毒株，横空出世，引起Nature和Science两大顶刊双双跟进报导，让人觉得这场变异毒株争霸赛可能还未到白热化阶段……
Nature报导标题：一种让人担忧的新冠变异毒株是如何悄悄扩散的 19重变异，到底具备哪些特性？ Nature之所以说这种变异株是“悄悄”扩散，是因为发现它“身怀绝技”的时候，实在有点晚了…… B.1.620早在今年2月就在欧洲出现，但是直到4月，立陶宛的研究者才对它进行了测序，这才暴露了它19重变异的身份。而立陶宛研究者之所以会对它进行测序，和立陶宛快速上涨的感染率有关，美国研究者推测B.1.620是当地疫情上扬的罪魁祸首。 那么，这19重变异到底有多强悍呢……看下面这张图。这是立陶宛研究者发布的预印本中的测序结果，第一行是B.1.620的变异点，图中所有涂色的格子都代表病毒具有这个变异点，红色的格子代表只有B.1.620拥有这个变异。
毒王争霸表，最后一行是最近抢眼的印度变异株，第一行是把变异表塞得满满当当的B.1.620。“明星”变异株P.1和B.1.351也在其中 可以看到，E484K这个臭名昭著的变异点——可以免疫逃逸——赫然在列。此外S477N这个变异点同样具备免疫逃逸能力。也就是说，B.1.620至少拥有两个免疫逃逸位点，而之前那些横扫南美威震欧洲雄踞印度的P.1、B.1.617、B.1.351之类的，可都只有一个免疫逃逸变异位点。 除了两个具备免疫逃逸能力的变异位点，在预印本中，研究者分析，B.1.620的N端结构域（N-Terminal Domain，简称NTD）的综合突变情况使得它能对抗中和抗体。 同时，B.1.620具备的P681H是能够增加传播性的，之前一度把英国闹得手忙脚乱的高传播性变异株B.1.1.7也拥有这个变异位点。 研究指出，这个19重变异的变异株中，有相当多变异点的功能和性质现在无法明确，因此，并不是说它只有三个变异位点有着危险的特质，而是剩下的某些变异暂时超出人类的知识范畴了…… 这满满当当的一大排变异里是否还会有什么“惊喜”和“惊吓”，现在还说不清楚。Science在针对这一变异株的报导中直接指出，“它是那种典型的需要拉响所有警报（raise all red flags）的变异株”。 B.1.620的传播情况如何？ 根据目前掌握的证据，研究者倾向于这种病毒起源于中非共和国和喀麦隆，通过航班传播至欧洲。但是由于非洲缺乏检测能力，该病毒在非洲的传播情况和覆盖面暂时无法得知。 而欧洲此前疲于应对P.1、B.1.617、B.1.351等变异株引发的疫情，而同时由于新冠病毒的变异速度极快，变异株非常多，使得欧洲也无法及时地筛出这株具备巨大威胁的新变异。研究保守估计，B.1.620在欧洲仍以旅行传播为主，暂且不能断言已经进入社区传播状态。 但不能否认的是，它已经在欧洲多点开花了……下图为研究者统计到的检出并上报的携带B.1.620的患者分布情况，色谱图标代表他们的旅行史，顶端的树状图显示的是病毒谱系，红色圈代表最早发现有旅行史的患者。从图中可以看到在欧洲检出的B.1.620变异株有一部分至少已经繁殖了两代了……
B.1.620在欧洲的分布和谱系图 据推测，B.1.620最早可能2月登陆欧洲，到4月得到的数据如图所示，还处在零零散散的状态。现在我们不能再以“没有快速传播说明它不厉害”而掉以轻心了，正在把南亚变成地狱的B.1.617也并不是一开始就立刻占领主要“市场份额”的，而B.1.620很可能有着比B.1.617更强的免疫逃逸能力，疫苗对它到底能起多大效果，依然未知…… B.1.617已经在逐渐接近我们，面对携带更多危险因素的B.1.620，“提高警惕，扎紧篱笆”，仍是一条必行之策。
参考文献
1.Gytis Dudas， Samuel L， Guy Baele，et al.Travel-driven emergence and spread of SARS-CoV-2 lineage B.1.620 with multiple VOC-like mutations and deletions in Europe medRxiv 2021.05.04.21256637； doi： https：//doi.org/10.1101/2021.05.04.21256637 2.https：//assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/984274/Variants_of_Concern_VOC_Technical_Briefing_10_England.pdf 3.Meredith Wadman。 Scientists tracking coronavirus variants struggle with global blind spots。 doi：10.1126/science.abj4775 4.Smriti Mallapaty。 How a worrisome coronavirus variant spread unnoticed。 doi： https：//doi.org/10.1038/d41586-021-01285-4 5。https：//www.dw.com/en/covid-19-african-variant-reveals-sequencing-lag/a-57586318 6.https：//www.ecdc.europa.eu/en/covid-19/variants-concern
什么补丁？疫苗吗
楼主对新冠变种和副作用很关心啊，
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很敬业的职业选手～～
楼主不是关心，是上班了。
当然关心，家里有人打了疫苗副作用挺大的，朋友也是。 不关心切身健康相关的，那关心什么？
如果这样，那倒是不怕，最多到时候加打一针了
副作用大指的是什么？发烧，头疼？这些比起得新冠你觉得哪个副作用大？