United States Patent Application 20170071964 Kind Code A1 Clarke; Michael O' Neil Hanrahan ; et al. March 16, 2017 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
Abstract Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ##STR00001## wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.
Inventors: Clarke; Michael O' Neil Hanrahan; (Redwood City, CA) ; Feng; Joy Yang; (Hillsborough, CA) ; Jordan; Robert; (Foster City, CA) ; Mackman; Richard L.; (Millbrae, CA) ; Ray; Adrian S.; (Burlingame, CA) ; Siegel; Dustin; (Half Moon Bay, CA) Applicant: Name City State Country Type
Gilead Sciences, Inc. Foster City CA US Family ID: 56997582 Appl. No.: 15/267433 Filed: September 16, 2016
64. The method of claim 39 further comprising administering a therapeutically effective amount of at least one other therapeutic agent or composition thereof selected from the group consisting of a corticosteroid, an anti-inflammatory signal transduction modulator, a .beta.2-adrenoreceptor agonist bronchodilator, an anticholinergic, a mucolytic agent, hypertonic saline and other drugs for treating a Coronaviridae virus infections; or mixtures thereof.
65. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus.
66. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus selected from SARS, MERS, 229E, NL63, OC43, and HKU1
67. The method of claim 39 wherein the Cornaviridae infection is caused by a SARS virus.
68. The method of claim 39 wherein the Cornaviridae infection is caused by a MERS virus.
69. The method of claim 39 wherein a Coronaviridae polymerase is inhibited.
United States Patent Application 20170071964 Kind Code A1 Clarke; Michael O' Neil Hanrahan ; et al. March 16, 2017 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
Abstract Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ##STR00001## wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.
Inventors: Clarke; Michael O' Neil Hanrahan; (Redwood City, CA) ; Feng; Joy Yang; (Hillsborough, CA) ; Jordan; Robert; (Foster City, CA) ; Mackman; Richard L.; (Millbrae, CA) ; Ray; Adrian S.; (Burlingame, CA) ; Siegel; Dustin; (Half Moon Bay, CA) Applicant: Name City State Country Type
Gilead Sciences, Inc. Foster City CA US Family ID: 56997582 Appl. No.: 15/267433 Filed: September 16, 2016
64. The method of claim 39 further comprising administering a therapeutically effective amount of at least one other therapeutic agent or composition thereof selected from the group consisting of a corticosteroid, an anti-inflammatory signal transduction modulator, a .beta.2-adrenoreceptor agonist bronchodilator, an anticholinergic, a mucolytic agent, hypertonic saline and other drugs for treating a Coronaviridae virus infections; or mixtures thereof.
65. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus.
66. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus selected from SARS, MERS, 229E, NL63, OC43, and HKU1
67. The method of claim 39 wherein the Cornaviridae infection is caused by a SARS virus.
68. The method of claim 39 wherein the Cornaviridae infection is caused by a MERS virus.
69. The method of claim 39 wherein a Coronaviridae polymerase is inhibited. dasanicool 发表于 2/4/2020 3:17:14 PM
“ The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus“ 赞
请你自己去看一下什么是compulsory licensing再说好吧,这里又没有墙 normally the person or company applying for a licence has to have tried, within a reasonable period of time, to negotiate a voluntary licence with the patent holder on reasonable commercial terms. Only if that fails can a compulsory licence be issued, and - even when a compulsory licence has been issued, the patent owner has to receive payment; Compulsory licensing must meet certain additional requirements: the scope and duration of the licence must be limited to the purpose for which it was granted, it cannot be given exclusively to licensees (e.g. the patent-holder can continue to produce), and it should be subject to legal review. 首先你要跟patent holder negotiate 人家不同意才能搞compulsory licensing,中国政府跟gilead商量了吗?完全是要绕过人家不带人家玩了,人家都跑到中国搞临床了,你要买licensing人家会不给你?而且即便是compulsory licensing也要照常付人家钱的。中国自己搞个专利什么意思?compulsory licensing里面也说了“it’s when the generic copy is produced mainly for the domestic market”,中国这个通过“PCT进入全球主要国家”又是什么意思? 要用人家的药,老老实实搞个license付人家钱不行吗?非要耍流氓???没看错还想靠这个新indication挣钱???这是什么恶心人的操作。shame on them!!!!!
, 请你自己去看一下什么是compulsory licensing再说好吧,这里又没有墙 normally the person or company applying for a licence has to have tried, within a reasonable period of time, to negotiate a voluntary licence with the patent holder on reasonable commercial terms. Only if that fails can a compulsory licence be issued, and - even when a compulsory licence has been issued, the patent owner has to receive payment; Compulsory licensing must meet certain additional requirements: the scope and duration of the licence must be limited to the purpose for which it was granted, it cannot be given exclusively to licensees (e.g. the patent-holder can continue to produce), and it should be subject to legal review. 首先你要跟patent holder negotiate 人家不同意才能搞compulsory licensing,中国政府跟gilead商量了吗?完全是要绕过人家不带人家玩了,人家都跑到中国搞临床了,你要买licensing人家会不给你?而且即便是compulsory licensing也要照常付人家钱的。中国自己搞个专利什么意思?compulsory licensing里面也说了“it’s when the generic copy is produced mainly for the domestic market”,中国这个通过“PCT进入全球主要国家”又是什么意思? 要用人家的药,老老实实搞个license付人家钱不行吗?非要耍流氓???没看错还想靠这个新indication挣钱???这是什么恶心人的操作。shame on them!!!!!
请你自己去看一下什么是compulsory licensing再说好吧,这里又没有墙 normally the person or company applying for a licence has to have tried, within a reasonable period of time, to negotiate a voluntary licence with the patent holder on reasonable commercial terms. Only if that fails can a compulsory licence be issued, and - even when a compulsory licence has been issued, the patent owner has to receive payment; Compulsory licensing must meet certain additional requirements: the scope and duration of the licence must be limited to the purpose for which it was granted, it cannot be given exclusively to licensees (e.g. the patent-holder can continue to produce), and it should be subject to legal review. 首先你要跟patent holder negotiate 人家不同意才能搞compulsory licensing,中国政府跟gilead商量了吗?完全是要绕过人家不带人家玩了,人家都跑到中国搞临床了,你要买licensing人家会不给你?而且即便是compulsory licensing也要照常付人家钱的。中国自己搞个专利什么意思?compulsory licensing里面也说了“it’s when the generic copy is produced mainly for the domestic market”,中国这个通过“PCT进入全球主要国家”又是什么意思? 要用人家的药,老老实实搞个license付人家钱不行吗?非要耍流氓???没看错还想靠这个新indication挣钱???这是什么恶心人的操作。shame on them!!!!!
United States Patent Application 20170071964 Kind Code A1 Clarke; Michael O' Neil Hanrahan ; et al. March 16, 2017 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
Abstract Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ##STR00001## wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.
Inventors: Clarke; Michael O' Neil Hanrahan; (Redwood City, CA) ; Feng; Joy Yang; (Hillsborough, CA) ; Jordan; Robert; (Foster City, CA) ; Mackman; Richard L.; (Millbrae, CA) ; Ray; Adrian S.; (Burlingame, CA) ; Siegel; Dustin; (Half Moon Bay, CA) Applicant: Name City State Country Type
Gilead Sciences, Inc. Foster City CA US Family ID: 56997582 Appl. No.: 15/267433 Filed: September 16, 2016
64. The method of claim 39 further comprising administering a therapeutically effective amount of at least one other therapeutic agent or composition thereof selected from the group consisting of a corticosteroid, an anti-inflammatory signal transduction modulator, a .beta.2-adrenoreceptor agonist bronchodilator, an anticholinergic, a mucolytic agent, hypertonic saline and other drugs for treating a Coronaviridae virus infections; or mixtures thereof.
65. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus.
66. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus selected from SARS, MERS, 229E, NL63, OC43, and HKU1
67. The method of claim 39 wherein the Cornaviridae infection is caused by a SARS virus.
68. The method of claim 39 wherein the Cornaviridae infection is caused by a MERS virus.
69. The method of claim 39 wherein a Coronaviridae polymerase is inhibited. dasanicool 发表于 2/4/2020 3:17:14 PM
可能老花眼,我上面的回复也没看清楚,帮你再贴一遍 https://pubchem.ncbi.nlm.nih.gov/compound/Remdesivirhttps://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1=20170071964.PGNR.&OS=DN/20170071964&RS=DN/20170071964 United States Patent Application 20170071964 Kind Code A1 Clarke; Michael O' Neil Hanrahan ; et al. March 16, 2017 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS Abstract Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ##STR00001## wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections. Inventors: Clarke; Michael O' Neil Hanrahan; (Redwood City, CA) ; Feng; Joy Yang; (Hillsborough, CA) ; Jordan; Robert; (Foster City, CA) ; Mackman; Richard L.; (Millbrae, CA) ; Ray; Adrian S.; (Burlingame, CA) ; Siegel; Dustin; (Half Moon Bay, CA) Applicant: Name City State Country Type Gilead Sciences, Inc. Foster City CA US Family ID: 56997582 Appl. No.: 15/267433 Filed: September 16, 2016 64. The method of claim 39 further comprising administering a therapeutically effective amount of at least one other therapeutic agent or composition thereof selected from the group consisting of a corticosteroid, an anti-inflammatory signal transduction modulator, a .beta.2-adrenoreceptor agonist bronchodilator, an anticholinergic, a mucolytic agent, hypertonic saline and other drugs for treating a Coronaviridae virus infections; or mixtures thereof. 65. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus. 66. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus selected from SARS, MERS, 229E, NL63, OC43, and HKU1 67. The method of claim 39 wherein the Cornaviridae infection is caused by a SARS virus. 68. The method of claim 39 wherein the Cornaviridae infection is caused by a MERS virus. 69. The method of claim 39 wherein a Coronaviridae polymerase is inhibited.
1.病毒所申请的应该是Method of Use专利,并没有composition claims。就是说分子结构的专利应该还在Gilead手里。但是只有method of use的专利并不表示病毒所有freedom to operate,就是说只要国内生产这个药,不管用作哪种用途,理论上都要向分子结构的所有方Gilead付费。而且专利申请不等于专利批准,如果Gilead当年申请原始专利的时候,提出的保护范围包括广谱的抗病毒疗效,像Ebola, SERS, MERS,, coronavirus等等,那么病毒所的专利申请至少在专利法比较完善的国家会被以不符合non-obvious的理由被拒。专利申请审批时间很长,最终这个申请会怎么样现在病毒所做大宣传没有什么意义。
2.如果看这个宣传,“在国家需要的情况下,暂不要求实施专利所主张的权利”,其实就是要求Gilead迫于人道主义压力不以composition claims被侵权的理由提起诉讼,我们自己再用待定Method of Use专利来用这个药物。如果Gilead不同意,那当然是美帝亡我之心不死。
上帝要人灭亡必先使其疯狂 Those whom God wishes to destroy, he first makes mad 《创世纪》第6章到第9章记载了诺亚方舟的历史。创造世界万物的上帝耶和华见到地上充满败坏、强暴和不法的邪恶行为,于是计划用洪水消灭恶人。同时他也发现,人类之中有一位叫做诺亚的好人。《创世纪》记载:“诺亚是个义人,在当时的世代是个完全人”[4]。耶和华神指示诺亚建造一艘方舟,并带着他的妻子、儿子(闪、含与雅弗)与媳妇。同时神也指示诺亚将牲畜与鸟类等动物带上方舟,且必须包括雌性与雄性。 当方舟建造完成时,大洪水也开始了,这时诺亚与他的家人,以及动物们皆已进入了方舟。《创世纪》如此形容洪水刚开始的景况:“当诺亚六百岁,二月十七日那一天,大渊的泉源都裂开了,天上的窗户也敞开了。四十昼夜降大雨在地上”[5]。洪水淹没了最高的山,在陆地上的生物全部死亡,只有诺亚一家人与方舟中的生命得以存活。 在220天之后,方舟在阿勒山附近停下,且洪水也开始消退。又经过了40天之后,阿勒山的山顶才露出。这时诺亚放出了一只渡鸦到处飞却不愿意飞回来,后来放出一只鸽子,但它并没有找到可以栖息的陆地就飞回来了。7天之后诺亚又再次放出鸽子,这次它立刻就带回了橄榄树的枝条,诺亚这时知道洪水已经散去。又等了7天之后,诺亚最后一次放出鸽子,这次它便不再回方舟了。诺亚一家人与各种动物便走出方舟。 离开方舟之后,诺亚将一只祭品献给神。耶和华闻见献祭的香气决定不再用洪水毁灭世界,并在天空制造了一道彩虹,作为保证。在《创世纪》中,神如此保证:“我使云彩盖地的时候,必有虹现在云彩中,我便纪念我与你们和各样有血肉的活物所立的约,水就再不泛滥、毁坏一切有血肉的物了”[6]。
1.病毒所申请的应该是Method of Use专利,并没有composition claims。就是说分子结构的专利应该还在Gilead手里。但是只有method of use的专利并不表示病毒所有freedom to operate,就是说只要国内生产这个药,不管用作哪种用途,理论上都要向分子结构的所有方Gilead付费。而且专利申请不等于专利批准,如果Gilead当年申请原始专利的时候,提出的保护范围包括广谱的抗病毒疗效,像Ebola, SERS, MERS,, coronavirus等等,那么病毒所的专利申请至少在专利法比较完善的国家会被以不符合non-obvious的理由被拒。专利申请审批时间很长,最终这个申请会怎么样现在病毒所做大宣传没有什么意义。
2.如果看这个宣传,“在国家需要的情况下,暂不要求实施专利所主张的权利”,其实就是要求Gilead迫于人道主义压力不以composition claims被侵权的理由提起诉讼,我们自己再用待定Method of Use专利来用这个药物。如果Gilead不同意,那当然是美帝亡我之心不死。
不是这个行业的,真不懂。交给专家去审核吧。我只是申请过专利,知道专利的一些基本常识。
http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1=20170071964.PGNR.&OS=DN/20170071964&RS=DN/20170071964
United States Patent Application 20170071964
Kind Code A1
Clarke; Michael O' Neil Hanrahan ; et al. March 16, 2017
METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
Abstract
Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: ##STR00001## wherein the 1' position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.
Inventors: Clarke; Michael O' Neil Hanrahan; (Redwood City, CA) ; Feng; Joy Yang; (Hillsborough, CA) ; Jordan; Robert; (Foster City, CA) ; Mackman; Richard L.; (Millbrae, CA) ; Ray; Adrian S.; (Burlingame, CA) ; Siegel; Dustin; (Half Moon Bay, CA)
Applicant:
Name City State Country Type
Gilead Sciences, Inc.
Foster City
CA
US
Family ID: 56997582
Appl. No.: 15/267433
Filed: September 16, 2016
64. The method of claim 39 further comprising administering a therapeutically effective amount of at least one other therapeutic agent or composition thereof selected from the group consisting of a corticosteroid, an anti-inflammatory signal transduction modulator, a .beta.2-adrenoreceptor agonist bronchodilator, an anticholinergic, a mucolytic agent, hypertonic saline and other drugs for treating a Coronaviridae virus infections; or mixtures thereof.
65. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus.
66. The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus selected from SARS, MERS, 229E, NL63, OC43, and HKU1
67. The method of claim 39 wherein the Cornaviridae infection is caused by a SARS virus.
68. The method of claim 39 wherein the Cornaviridae infection is caused by a MERS virus.
69. The method of claim 39 wherein a Coronaviridae polymerase is inhibited.
就是!完全赞同你这句话。你应该是专业人士吧,由美国专利了吧,牛!
我不明白为什么你会编故事?
强制许可权的前提,是证明药品公司无法生产足够的药品,用来应对危机。
哪怕真的无法生产,也可以授权给第三方生产,收取专利费。
“行使强制许可权”、免费仿制的情况,是不存在的。
如果他愿意的话,也行。
请看298楼的美国专利信息
所以他们这么做是防国内"同行"?
万一下次新病毒又出来,再去偷别人家的研究成果???
美国的生物实验室中国人很多,为美国生物制药贡献不少,为什么同样的中国人回到中国大多研究不出什么了?
“ The method of claim 39 wherein the Coronaviridae infection is caused by a Coronaviridae virus“
赞
你才是编故事呢,哪里有需要“证明药品公司无法生产足够的药品的前提"?前提有,但不是你说的这个。我并没有说免费仿制, “行使强制许可权”, 也是要对专利持有者付费的,但这个付多少不是专利持有者说了算,而是各国法律自定的。
不明白武汉病毒所为什么在这么敏感的时候,自己给自己挖坑?
里外不是人:
对内,早就知道药物有效却保持沉默。再结合武汉病毒所一个感染的都没有等消息,这不是让人诟病吗?
对外,丢人不?丢人不?看大家之前的科普:当年埃博拉病毒的时候,这个药就出来了,广谱,但是效果不如另外两个药,所以没用,没想到这次病毒效果不错。全世界都知道这个药是积了德公司的,武汉病毒所这时候干这事,丢人不?
请你自己去看一下什么是compulsory licensing再说好吧,这里又没有墙 normally the person or company applying for a licence has to have tried, within a reasonable period of time, to negotiate a voluntary licence with the patent holder on reasonable commercial terms. Only if that fails can a compulsory licence be issued, and - even when a compulsory licence has been issued, the patent owner has to receive payment; Compulsory licensing must meet certain additional requirements: the scope and duration of the licence must be limited to the purpose for which it was granted, it cannot be given exclusively to licensees (e.g. the patent-holder can continue to produce), and it should be subject to legal review. 首先你要跟patent holder negotiate 人家不同意才能搞compulsory licensing,中国政府跟gilead商量了吗?完全是要绕过人家不带人家玩了,人家都跑到中国搞临床了,你要买licensing人家会不给你?而且即便是compulsory licensing也要照常付人家钱的。中国自己搞个专利什么意思?compulsory licensing里面也说了“it’s when the generic copy is produced mainly for the domestic market”,中国这个通过“PCT进入全球主要国家”又是什么意思? 要用人家的药,老老实实搞个license付人家钱不行吗?非要耍流氓???没看错还想靠这个新indication挣钱???这是什么恶心人的操作。shame on them!!!!!
这不是证明你前面说的前提 "证明药品公司无法生产足够的药品的前提" 是编故事?
人家来做clinical trial 说明什么,没有clinical trial 任何药都不能上市,而现在只有中国才有那么大的 sample 做 clinical trial。
分子式专利和使用专利并不冲突,申请这个专利,怎么就证明不会和 gilead 商量了?
如果要那各国还要”强制许可专利“这条法律干什么?你还有没有基本的逻辑分析能力
成天假设别人撒流氓的,一定是自己经常撒流氓, 你这种人才是恶心, shame on you
搞清楚。不是申请一个新药,是申请药物的新用途。如果你还是不懂专利是怎么运作的,得先去做做功课。全球通用的准则,怎么到了这里就是中国的问题了呢
看看298楼我贴的美国专利细节,冠状病毒用途已经包括。如果有什么解读,欢迎发出来
那你还去抢注!
就是制毒所 什么病毒所。。。。
赞一下
所以呢?真是美国专利受理了那病毒所的就被据了呗,对我对你对大家有什么损失?一样的一个药一样的适应症。
但是我们不能因为自己想要表达什么声音,而且已经在权威的平台上表达过了(说的是PCT不是华人),就拒绝不同的发声,这样的话和共党下的中国有什么区别?
再说一遍,就专利申请来指责武汉所,是没有根据的。我自己都可以申请Gilead新药可以治新肺,可以杀蟑螂,甚至可以治疗阿兹海默。只要没有申请的,我都可以申请,前提是我能支付专利费。我不能生产这个药,但是我知道了药品化学式,国际专利法保护了我可以申请这个药没有被发现的新用途,只要和原专利不冲突。多少专利公司靠这个吃饭的
这个说得清楚,赞
关键天朝百姓不懂这些。他们只知道他们的人民科学家搞出了重大突破,跟美国没有半毛钱关系。将来美国不乐意了,那还是美帝抢了他们人民科学家的功劳呢。
是的。是新用途而不是制剂或化学品。这就是说不管怎么样武汉所不能生产这个药(前提是中国不会像印度一样强制仿制药)
那只能靠华人大妈去教育他们了
1. 武毒所都已经在1/21前把药搞清了,但就是不给群众用,就是要让武汉等多个城市封城,让群众死伤惨重,就是要拖到美国第一例治疗有效后,才跳出来
2. 武毒所(或某些人)鸡贼,为了我的国的面子,不得不造假
小粉们选一个吧
所以你的意思就是,我就试试偷一下你家,看你的防盗措施严不严密,偷成了是你活该,偷不成对你也没损失啊?反正是法律允许的嘛。是没错多少专利流氓都是靠这个吃饭的。可是在这个举国抗疫的节骨眼上,一群拿着国家资金,本该以科研为己任的科学家不但不做贡献,反而干这种事,要不要脸啊?!
专利流氓是不违法,想要靠这个挣钱也不违法,别人怒骂唾弃这种流氓怎么了?照样也不违法!
这个要看中国专利局的操守了,新冠状病毒是冠状病毒的下位概念,也可以解读为有创造性的。虽然这么做很可能会引起专利界的哗然,但这么巨大的利益面前,也不一定做不出来,拭目以待吧。
另外我比较好奇的是武汉病毒研究所是怎么得到1月21日的申请日的,如果这个申请是纸件提交的 ,有可能是邮局给了个假邮戳
我前面说什么了,麻烦你看清了再喷
我在上层提到了武汉病毒所提交1月21日专利申请的可能性,就是用假邮戳,邮寄交纸件。中国的专利申请日是以邮戳日算的
是啊没办法,这就是专利。你可以尽情唾弃,但是有啥用呢。武汉所申请专利于情于理都是合法的(就我目前看到的)。
专利就是这么个意思,你门把的不严,我就进来偷点东西。你把的严呢,我就讨价还价。每个公司都是这样啦,没必要上升到国难家仇。
你可以说他们不顾举国抗疫,但是现在有那个研究所研究机构不是以专利为己任呢。而且我之前也说了,如果他们拿到了数据(证明有效)但是用数据去申请专利而不是上报,那是另外一个冷血的故事。
我知道了,你不认识Coronaviridae。。。。。我来教你,这是一个family的名字,所有的coronavirus都是这个family里的,人家gilead有这个application的专利,屁的新用途。读点书再来喷?
她应该不认识Coronaviridae,大概觉得跟coronavirus不是一个东西
这个问题提得好!
先了解一下申请专利的程序再来喷ok?尤其是PCT
PCT了解一下再发言OK?
呵呵,有人企图强奸,但是强奸未遂,你说,这有什么,反正有警察,他想强奸不会成功的,你们怎么能因为他企图强奸骂他呢?????
这个就需要按照您圣驾的意思修改国际上通用的专利准则了。麻烦您去改改,改好了让我等屁民知道也好
Gilead早就在动物上试验过对冠状病毒类似MERS的疗效,只是没有临床试验而已。
可以这么偷吗?
没脸没皮!
美国的那个例子文章发表和见诸报端都是 1/31, 这个的文章收到是 1.25 号,肯定不是抄袭
但是够不够新颖,够不够专利,那是另外一个问题,毕竟还没有批准
但各大科技公司对专利这么操作的屡见不鲜
那片文章不说明是特效药,美国的那个例子也不说明是特效药
可以用假邮戳制造假专利申请日。如果申请提前公开的话,四五个月后可以看到公开的专利文本,可以看看到底怎么交的,怎么写的
他们在 natural 上的文章是公开的啊, 1-25收到的
p。武汉所也递交了PCT,假邮戳啥的可以歇歇了
那就不知道了
那就是说早知道有药可治,然后看着这么多人死?再联想如果病毒本来就是从它那来的。。。细思极恐啊
https://www.nature.com/articles/s41422-020-0282-0
Wang, M., Cao, R., Zhang, L. et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res (2020). https://doi.org/10.1038/s41422-020-0282-0 Download citation
Received[size=1.6]25 January 2020
Accepted[size=1.6]28 January 2020
Published[size=1.6]04 February 2020
在理
没什么好争论的, gilead公司怎么决定免费的这一过程我都知道些。 公司确实免费把所有资料给了中国。 这是这边医药界很多人都知道的事情了。 gilead已经决定全部给中国的时候, 对后面这些事也无所谓了。 只是中国搞病毒这帮人的操作显得很low。病毒所估计是想独家拥有, 然后靠卖专利赚一笔。太low了!
不过冠状肺炎多少年才爆发一次? 即使拿了这个也没啥大用处, 病毒所也许是想抢名儿, 可惜,全世界都知道是gilead公司搞出来的, 这个名儿人家公司已经有了, 病毒所只能在中国自嗨时吹了。
怪不得全所1500人 没一个感染 可以自己治啊
不是自杀 而是刑事案件 轮不到他们自行了断
明白了,谢谢mm解释,手动点赞
在全世界的人面前裸奔啊。
丢死人了。