Research Most of the research in our laboratory has used coronaviruses as models to study the genetics of RNA virus transcription, replication, persistence, and cross species transmission. We have also been using alphavirus vaccine vectors to develop novel candidate vaccines against caliciviruses. Specific areas of interest include: 1. Coronavirus Reverse Genetics and vaccine development. We have developed infectious cDNAs from two coronaviruses. Specific applications include: a) studying critical cis and trans acting factors that regulate coronavirus subgenomic mRNA synthesis and replication, b) rearranging the coronavirus gene order to study genome evolution and function in coronavirus transcription and replication, c) identification of the minimal coronavirus genome, d) development of coronavirus replicon RNAs and coronavirus replicon particles for vaccine development, e) expression of heterologous genes from coronavirus vaccine vectors for swine and other important species. 2. Norwalk like virus (Calicivirus) vaccine development. 看到一点点关键词，就扑上去捕风捉影，正是阴谋论特色。 而这些专业名词，对外行吃瓜群众来说，又觉得似乎很有道理。阴谋论，总有一款适合你。LOL
第一作者，通讯作者都是美国实验室， 北卡大学的。 合作者还包括FDA， 与武汉病毒研究所的合作。可以说这篇主要是北卡这个实验室的。
这是这位北卡教授实验室网页
https://www.med.unc.edu/microimm/directory/ralph-baric-phd-1/
Research Most of the research in our laboratory has used coronaviruses as models to study the genetics of RNA virus transcription, replication, persistence, and cross species transmission. We have also been using alphavirus vaccine vectors to develop novel candidate vaccines against caliciviruses. Specific areas of interest include: 1. Coronavirus Reverse Genetics and vaccine development. We have developed infectious cDNAs from two coronaviruses. Specific applications include: a) studying critical cis and trans acting factors that regulate coronavirus subgenomic mRNA synthesis and replication, b) rearranging the coronavirus gene order to study genome evolution and function in coronavirus transcription and replication, c) identification of the minimal coronavirus genome, d) development of coronavirus replicon RNAs and coronavirus replicon particles for vaccine development, e) expression of heterologous genes from coronavirus vaccine vectors for swine and other important species. 2. Norwalk like virus (Calicivirus) vaccine development. 看到一点点关键词，就扑上去捕风捉影，正是阴谋论特色。
而这些专业名词，对外行吃瓜群众来说，又觉得似乎很有道理。阴谋论，总有一款适合你。LOL
水太大没看到
就看到一个楼里（都忘了那个楼了）说神马人工合成病毒 P4 阴谋论
我贴这个就是想说，这个就是国际合作灌水，拿这个宣扬P4 阴谋论，跟另外楼里提到国内有的极端言论宣扬美国阴谋论，都一样荒谬。而且这个还是合作成果。把公开的科研当作阴谋论没有事实与逻辑基础。
谢谢哈