纽约时报新闻,又有两起疫苗后血小板减少到零的病例

日月茗
楼主 (文学城)

https://www.nytimes.com/2021/02/08/health/immune-thrombocytopenia-covid-vaccine-blood.html

Hematologists with expertise in treating immune thrombocytopenia said they suspected that the vaccine did play a role. But they said that cases after vaccination were likely to be exceedingly rare, possibly the result of an unknown predisposition in some people to react to the vaccine by developing an immune response that destroys their platelets. The disorder has occurred, rarely, in people who received other inoculations, particularly the measles-mumps-rubella one.

In its most common form, immune thrombocytopenia is an autoimmune disease that affects about 50,000 people in the United States, according to a support group for patients. The condition develops when the immune system attacks platelets or the cells that create them, for unknown reasons. It sometimes follows a viral illness, and can persist for months or become chronic and last for years. It is generally treatable. Professional groups have advised that patients with the disorder be vaccinated for Covid, but after consulting with their hematologists.

吃与活
看来疫苗诱发的血小板减少是真的。两个病人的认识令人敬佩。
杨别青
这是第二次报道了,新冠疫苗接种造成15例有血小板异常病史的人血小板减少,因果关系提示比较明显。
p
pickshell
记得好几次烈性传染性病毒疫情,都有“病毒性出血热”(血小板减少)比如Ebola virus。

“病毒性出血热”挺恐怖的,很多病人一旦出现这,扛不过几天就。。唉

志在千里
谢谢分享!已经有36例ITP了。儿童打MMR也有ITP,那是减活疫苗。但小朋友血小板很少到O, 用IVIG血小板反弹厉害

谢谢分享!已经有36例ITP了:( 儿童打MMR也有ITP,那是减活疫苗。但小朋友血小板很少到零, 颅内出血基本没有。用IVIG血小板也反弹厉害,转慢性也比较少。成人了,没好事了:(

MMR vaccine-related ITP usually occurs within six weeks of vaccination. In most cases, it is mild and presents with only bruising and petechiae. Platelet counts are higher than in the case of non-vaccine-associated ITP (> 20,000 × 109/L in 33–19% of patients).Jan 16, 2013   Vaccine administration and the development of immune ... www.ncbi.nlm.nih.gov › pmc › articles › PMC3899154            
志在千里
James Bussel医师收集了15个打新冠疫苗后患ITP的病例,写文章警告和帮助医患,也是英雄。

James Bussel, a hematologist and professor emeritus at Weill Cornell Medicine who has written more than 300 scientific articles on the platelet disorder。。。

 

杨别青
36例ITP都是与COVID-19 疫苗相关吗?
志在千里
楼主的纽时文章里有连接

。。。

More than 31 million people in the United States have received at least one dose, and 36 similar cases had been reported to the government’s Vaccine Adverse Event Reporting System, VAERS, by the end of January. 。。。

志在千里
Ebola出血热的情况比ITP更复杂, 有DIC 等很多情况。。。, 哭
杨别青
有血小板问题的人应该等新冠蛋白疫苗
志在千里
疫苗和ITP的关系 , 提到了三种不同的疫苗,MMR, 流感, Shingles

https://www.itpsupport.org.uk/index.php/en/vaccinations-and-itp

MMR vaccination

Seasonal influenza vaccination

Shingles vaccination

杨别青
看到了,大概百万人一个得ITP病,比MMR引发的几率要低,后者10万人中1-2个
T
TBz
注意到这段文字

It is not known whether this blood disorder is related to the Covid vaccines. More than 31 million people in the United States have received at least one dose, and 36 similar cases had been reported to the government's Vaccine Adverse Event Reporting System, VAERS, by the end of January. The cases involved either the Pfizer-BioNTech or Moderna vaccine, the only two authorized so far for emergency use in the United States.

But the reporting system shows only problems described by health care providers or patients after vaccination, and does not indicate whether the shots actually caused the problems.

Officials with the Food and Drug Administration and the Centers for Disease Control and Prevention said that they were looking into the reports, but that so far, rates of the condition in vaccinated people did not appear higher than the rates normally found in the U.S. population, so the cases could be coincidental. 

这是说坐在家里啥也不干也会得这病?

 

杨别青
相关性应该采用不同的关联算法,
日月茗
哪个公司在做新冠蛋白疫苗?
日月茗
上次佛州去世的医生打的是Pfizer 疫苗,文中这两例打的是Moderna疫苗

这两人也是打针后血小板降为零,平时好像是没有血液问题的。虽然救过来了,但是Dr.Bussel和他同事发表的文章里有说这类病人

"It also notes that it is too soon to tell whether the affected patients will have lasting recoveries, or recurrences of the platelet problem."

Dr.Bussel文中提到的15例,有的是本人已有血小板减少症或自身免疫疾病的,反正打完疫苗后更低了。

政府数据库里在1月底有36份类似的案例。

我估计这些人可能不会去打反应更强烈的第二针了。

 

 

B
Blue_Snow
这是新闻报道的解释
p
pickshell
疫苗怎么会引发这个? 说实在想不通啊,是不是原本就患有什么病?应查查病史。

曾有位同学,患流感只要拖久还没好,小腿就出现紫癜,

我没能看到LZ链接全文,读一半后就自动跳转,得输入EMAIL才能让读。。,

杨别青
Novavax目前在进行临床三期试验,纳米蛋白疫苗
杨别青
提示病毒可能引发异常免疫
B
Blue_Snow
不是mRNA不是病毒吗?
杨别青
关于政府36份类似的案例,能否给一个链接?多谢
杨别青
不同的原因,病毒疫苗和mRNA疫苗都与ITP相关
B
Blue_Snow
政府数据库应该就指Vaers 疫苗副作用报告系统。不要跑到CDC去
杨别青
谢谢