FDA authorizes COVID-19 vaccine boosters for the immunocompromised Karen Weintraub USA TODAY
The less than 3% of Americans who are severely immunocompromised should be able to get an extra dose of the Pfizer or Moderna COVID-19 vaccine, the federal government decided Thursday.
People who are on medications or have diseases that suppress their immune system may not have gotten adequate protection from their earlier doses of COVID-19 vaccine and are more likely to mount a response to an additional dose, the Food and Drug Administration determined.
"Making the booster shots available to us is imperative," said Michele Nadeem-Baker, a patient with chronic lymphocytic leukemia, a type of blood cancer. "The immunocompromised community has felt forgotten This gives us hope that we have not been."
A study in people with solid organ transplants, for instance, showed only about 15% had an immune response to the first dose and roughly half mounted one to a second dose. Later research found a quarter of those with no response to the first two doses responded to a third. Even those who had an antibody response had a lower one than those with normal immune systems.
It's not clear how many of those infected after vaccination are transplant patients or otherwise immunocompromised, but anecdotally, doctors have reported that they make up a large percentage of those hospitalized with so-called breakthrough infections.
“Today’s action allows doctors to boost immunity in certain immunocompromised individuals who need extra protection from COVID-19," Dr. Janet Woodcock, the FDA’s acting commissioner, said in a statement. "As we’ve previously stated, other individuals who are fully vaccinated are adequately protected and do not need an additional dose of COVID-19 vaccine at this time."
The FDA did not mention the immune-compromised patients who received the single-dose Johnson & Johnson vaccine.
At City of Hope, a private, nonprofit hospital and research center in Duarte, California, for example, "we are seeing more and more immunosuppressed people," said Dr. John Zaia, a professor of pediatrics.
https://www.usatoday.com/story/news/health/2021/08/12/fda-immunocompromised-covid-19-vaccine-booster-shots/8105494002/
FDA authorizes COVID-19 vaccine boosters for the immunocompromised Karen Weintraub USA TODAYThe less than 3% of Americans who are severely immunocompromised should be able to get an extra dose of the Pfizer or Moderna COVID-19 vaccine, the federal government decided Thursday.
People who are on medications or have diseases that suppress their immune system may not have gotten adequate protection from their earlier doses of COVID-19 vaccine and are more likely to mount a response to an additional dose, the Food and Drug Administration determined.
"Making the booster shots available to us is imperative," said Michele Nadeem-Baker, a patient with chronic lymphocytic leukemia, a type of blood cancer. "The immunocompromised community has felt forgotten This gives us hope that we have not been."
A study in people with solid organ transplants, for instance, showed only about 15% had an immune response to the first dose and roughly half mounted one to a second dose. Later research found a quarter of those with no response to the first two doses responded to a third. Even those who had an antibody response had a lower one than those with normal immune systems.
And a study published Wednesday confirmed the benefit of a third dose among transplant patients.
It's not clear how many of those infected after vaccination are transplant patients or otherwise immunocompromised, but anecdotally, doctors have reported that they make up a large percentage of those hospitalized with so-called breakthrough infections.
“Today’s action allows doctors to boost immunity in certain immunocompromised individuals who need extra protection from COVID-19," Dr. Janet Woodcock, the FDA’s acting commissioner, said in a statement. "As we’ve previously stated, other individuals who are fully vaccinated are adequately protected and do not need an additional dose of COVID-19 vaccine at this time."
The FDA did not mention the immune-compromised patients who received the single-dose Johnson & Johnson vaccine.
At City of Hope, a private, nonprofit hospital and research center in Duarte, California, for example, "we are seeing more and more immunosuppressed people," said Dr. John Zaia, a professor of pediatrics.
说实在话，学了这么多的知识，特别是近期有关疫苗的知识，我不怕现在被感染。
一旦被感染，比如厉害的Delta变异，我会是无症状，最不济也是中等症状者，在最初的五六天里，我的抗体会起作用，之后即使抗体不够，我的细胞免疫也会被唤醒，持续产生抗体。
还是得去测S蛋白spike protein才能决定？
前两天法眼写道：https://bbs.wenxuecity.com/health/986081.html
我开始是喉咙痛，看过医生，之后发展到咳嗽。吃了OTC的止咳药、润喉糖、川贝枇杷膏，慢慢就好了。按照我10年前几次咳嗽的经历，如果吃一点抗生素，会有帮助。但是医生以喉部化验不出细菌为由，不肯给我开。
没测核酸，主要原因是：
1）我自己看见喉咙红肿溃烂，认为这就是原发病灶。而新冠是全身性疾病，喉咙痛只是表象。
2）我问医生，从医学角度，你建议测核酸吗？医生说，从医学角度，我认为不需要，虽然现在测一下很方便。
3）医生跟我说，你打过疫苗，家里人也都打过，没必要测。言下之意，中招了也没啥大事。
4）当时本地疫情比较平缓，Delta还未开始。医生说，我们这里现在很少发现阳性。
估计下一轮就是高龄者。
先是娃嗓子痛，带他去看大夫。大夫说没啥事，打过疫苗了不会是新冠，不用测。
我自己懒得去看大夫，去测了个新冠。