A 74-year-old man showed acute confusion after preparation for cataract operation in day surgery clinic. The patient became confused and agitated after instillation of topical cyclopentolate drop into the eye and the symptoms persisted over several hours.
Diagnosis:
Previously the patient had been diagnosed with amnestic MCI with the finding of bilateral medial temporal atrophy on brain magnetic resonance imaging. 18F-flutemetamol positron emission tomography scan demonstrated multifocal amyloid deposition in the brain.
身体不错，但视力出现问题，因为儿子在波士顿工作，所以来这里看眼睛。经检查，是白内障，可以考虑手术，但突然他失去了知觉，家人打911送急诊，苏醒后并无大碍，但短期记忆完全丧失，自己感到很困惑，不明白为什么会在波士顿？
医生认为可能是小中风，做了各项检查，认知毫无问题，从生活常识到总统选举对答如流，腿脚活动也毫无问题。MRI等监测发现脑健康程度相当于五十多岁的人，丝毫没有中风的迹象。但就是把最近两个星期的事情忘得一干二净。
年轻的医生觉得无法解释和诊断，只好请来了老专家，立刻就找到了问题的根源。
感兴趣的可以猜猜。
https://www.mayoclinic.org/zh-hans/diseases-conditions/transient-global-amnesia/symptoms-causes/syc-20378531
据说过量散瞳药会完全“抹掉”近期记忆。
只不过是用点的，不是用口服的。
A 74-year-old man showed acute confusion after preparation for cataract operation in day surgery clinic. The patient became confused and agitated after instillation of topical cyclopentolate drop into the eye and the symptoms persisted over several hours.
Diagnosis:Previously the patient had been diagnosed with amnestic MCI with the finding of bilateral medial temporal atrophy on brain magnetic resonance imaging. 18F-flutemetamol positron emission tomography scan demonstrated multifocal amyloid deposition in the brain.
source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909168/
此人应该脑部有问题。
顺着这个思路，是不是可以找到治疗老年呆痴的方法？
害怕不敢做散瞳眼睛检查了。罕见，而且是过量。技术员水平不够。
在这里才做了几年验光师，就碰上了一回。
“短期记忆丧失可能是由于散瞳药物中的生物碱类成分穿过血脑屏障，影响了大脑中与记忆有关的部分。具体来说，生物碱类成分可能会影响神经递质的释放和再摄取，干扰神经元之间的通信，从而导致短期记忆功能的损害。”