Paxlovid—Pfizer’s antiviral Covid-19 treatment—is 37% effective at preventing hospitalization or death in high-risk patients compared with no treatment, according to a studypublished Thursday in the JAMA Network Open, well below the 88% effectiveness rate Pfizer and regulators reported in clinical trials in 2021
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The study also found another antiviral Covid-19 treatment, Merck’s Lagevrio, was 42% effective in preventing hospitalization or death and 77% effective against death alone.
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Why the effectiveness has fallen. The study authors noted the clinical trials were conducted among unvaccinated patients who had limited natural immunity, whereas this study was conducted in a real-world population including vaccinated and previously infected patients who had some other defenses against the coronavirus. They also noted the original clinical studies were completed when the Delta variant was the most common strain of the virus while their study was conducted when the Omicron variant was, suggesting that the drug could work differently with different strains.
高中生得了 COVID， 可以吃 Paxlovid 吗？ 好处和坏处？
https://www.forbes.com/sites/willskipworth/2023/09/21/covid-drug-paxlovid-now-less-effective-than-in-early-trials-but-its-still-great-at-preventing-death/?sh=124adbe3c44f
Paxlovid—Pfizer’s antiviral Covid-19 treatment—is 37% effective at preventing hospitalization or death in high-risk patients compared with no treatment, according to a studypublished Thursday in the JAMA Network Open, well below the 88% effectiveness rate Pfizer and regulators reported in clinical trials in 2021
………………
The study also found another antiviral Covid-19 treatment, Merck’s Lagevrio, was 42% effective in preventing hospitalization or death and 77% effective against death alone.
…………、
Why the effectiveness has fallen. The study authors noted the clinical trials were conducted among unvaccinated patients who had limited natural immunity, whereas this study was conducted in a real-world population including vaccinated and previously infected patients who had some other defenses against the coronavirus. They also noted the original clinical studies were completed when the Delta variant was the most common strain of the virus while their study was conducted when the Omicron variant was, suggesting that the drug could work differently with different strains.
而且，这药不能减少long Covid
https://www.usnews.com/news/health-news/articles/2023-10-31/paxlovid-probably-wont-your-cut-odds-for-long-covid-study
避免刀片喉和咳嗽加重。没胃口喝点小米粥，吃蒸鸡蛋，喝萝卜汤。注意不要急于大运动量锻练。
我LD这次从欧洲回来就病了，38度多咳嗽浑身不舒服，躺床上那猴样像快死的人，吃了药第二天就没事了。
他没有基础病，就是那种对生病零容忍的熊。