Some of the polio vaccine administered from 1955–1963 was contaminated with a virus, called simian virus 40 (SV40). The virus came from the monkey kidney cell cultures used to produce the vaccine. Most, but not all, of the contamination was in the inactivated polio vaccine (IPV). Once the contamination was recognized, steps were taken to eliminate it from future vaccines. Researchers have long wondered about the effects of the contaminated vaccine on people who received it. Although SV40 has biological properties consistent with a cancer-causing virus, it has not been conclusively established whether it might have caused cancer in humans. Studies of groups of people who received polio vaccine during 1955–1963 provide evidence of no increased cancer risk. However, because these epidemiologic studies are sufficiently flawed, the Institute of Medicine's Immunization Safety Review Committee concluded that the evidence was inadequate to conclude whether or not the contaminated polio vaccine caused cancer. In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research.
Copyright 2003 by the National Academy of Sciences. All rights reserved.
In 1960, it was discovered that Simian Virus 40 (SV40) contaminated up to 30% of the poliovirus vaccines in the US. This contamination arose because the vaccines were produced in monkey kidney cell cultures harboring SV40 between 1955 and 1963. During this period, approximately 90% of children and 60% of adults in the USA were inoculated for polio and possibly exposed to SV40. Many epidemiologic and molecular pathogenesis studies have been conducted in order to identify potential cancer risks since this 'natural' experiment began. Productive SV40 infection has the potential to initiate malignancy in a variety of target tissues. Epidemiological studies that investigated the relationship between SV40 infection and cancer risks have yielded mixed results. Studies can be grouped into three categories based on their exposure definition of SV40 infection: (1) use of vaccination or birth cohorts as proxy variables for infection, (2) follow-up of children of pregnant women who received polio vaccines, and (3) direct molecular detection of the virus or serologic detection of anti-SV40 antibody responses. A meta-analysis of five published studies did not support the hypothesis that SV40 exposure increases the overall risk of cancer incidence or cancer mortality. The analysis of specific cancer sites is largely inconclusive because of substantial problems that most studies have had in reliably defining exposure, defining latency effects, or dealing with confounding and other biases. A new generation of molecular epidemiologic studies is necessary to properly address these issues.
好像我啥都不知道. 一样. lol
其实那几个同学自己才是知道很少.
在大陆70年代初的时候根本没有癌症这个词. 大概75年后国内才慢慢有癌症患者.
在美国也一样. 不过要早一些. 原因是什么早就不是什么阴谋论了. 他们早就已经公开告诉大家是怎么回事了. 只是大家根本没去看而已.
多的我懒得说了. 自己去研究就好了.
Some of the polio vaccine administered from 1955–1963 was contaminated with a virus, called simian virus 40 (SV40). The virus came from the monkey kidney cell cultures used to produce the vaccine. Most, but not all, of the contamination was in the inactivated polio vaccine (IPV). Once the contamination was recognized, steps were taken to eliminate it from future vaccines. Researchers have long wondered about the effects of the contaminated vaccine on people who received it. Although SV40 has biological properties consistent with a cancer-causing virus, it has not been conclusively established whether it might have caused cancer in humans. Studies of groups of people who received polio vaccine during 1955–1963 provide evidence of no increased cancer risk. However, because these epidemiologic studies are sufficiently flawed, the Institute of Medicine's Immunization Safety Review Committee concluded that the evidence was inadequate to conclude whether or not the contaminated polio vaccine caused cancer. In light of the biological evidence supporting the theory that SV40-contamination of polio vaccines could contribute to human cancers, the committee recommends continued public health attention in the form of policy analysis, communication, and targeted biological research.
Copyright 2003 by the National Academy of Sciences. All rights reserved.
Polio vaccines, Simian Virus 40, and human cancer: the epidemiologic evidence for a causal association - PubMed (nih.gov) Tam Dang-Tan 1, Salaheddin M Mahmud, Riccardo Puntoni, Eduardo L Franco Affiliations expand PMID: 15322523 DOI: 10.1038/sj.onc.1207877 AbstractIn 1960, it was discovered that Simian Virus 40 (SV40) contaminated up to 30% of the poliovirus vaccines in the US. This contamination arose because the vaccines were produced in monkey kidney cell cultures harboring SV40 between 1955 and 1963. During this period, approximately 90% of children and 60% of adults in the USA were inoculated for polio and possibly exposed to SV40. Many epidemiologic and molecular pathogenesis studies have been conducted in order to identify potential cancer risks since this 'natural' experiment began. Productive SV40 infection has the potential to initiate malignancy in a variety of target tissues. Epidemiological studies that investigated the relationship between SV40 infection and cancer risks have yielded mixed results. Studies can be grouped into three categories based on their exposure definition of SV40 infection: (1) use of vaccination or birth cohorts as proxy variables for infection, (2) follow-up of children of pregnant women who received polio vaccines, and (3) direct molecular detection of the virus or serologic detection of anti-SV40 antibody responses. A meta-analysis of five published studies did not support the hypothesis that SV40 exposure increases the overall risk of cancer incidence or cancer mortality. The analysis of specific cancer sites is largely inconclusive because of substantial problems that most studies have had in reliably defining exposure, defining latency effects, or dealing with confounding and other biases. A new generation of molecular epidemiologic studies is necessary to properly address these issues.
楼上夫子一针见血,不做细致展开。
这世界不是以你的孤陋寡闻为存在标准。
清楚记得家里长辈说某种食物致癌,我们热烈讨论”致癌“和”治癌“的区别。
要是我跟你说文革前就亲眼见到过几例癌症死亡病例,你说没证据。
柯庆施知道吧?64年,癌症。他的前任,陈毅知道吧,72年肠癌病故。他的上司,周恩来,至少75年前就确诊膀胱癌。这几位都是副总理以上的大官,所以我们知道了。不知道的不知有多少。
小仙,教你一招:说有易,说无难。记住。
楼主没听说不奇怪,因为他太年轻,而且两耳不闻窗外事。
你说的清楚得不能再清楚了:"在大陆70年代初的时候根本没有癌症这个词."
怎么也描不白了,越来越黑。
只能反映出你的孤陋寡闻,集合一些志同道合者抱团寻找真相就很好了,别费力气推销了,漏洞百出。
孙中山之死 - 维基百科,自由的百科全书 (wikipedia.org)
开始怕癌症. 这都是那时候开始的.
这些都是简单的事实.
你多少岁当然有关系了. 关系就是你是不是在说谎. 说啊. 也许你没出生前就在读人民日报了.
当时没啥检测手段.凡是恶性和不知道的病都变成癌症了.
维基:1966年2月1日,河南省人民政府授予焦裕禄革命烈士称号[7]。1966年2月6日,署名穆青、冯健、周原的长篇通讯《县委书记的榜样——焦裕禄》由新华社发表。1966年2月7日晨,中央人民广播电台播送了这篇通讯[8]。1966年2月7日,《人民日报》发表了社论《向毛泽东同志的好学生焦裕禄学习》以及长篇报道《县委书记的榜样——焦裕禄》[7]。
即使是7几年写的,焦的癌症是60年代的事情吧。
放心,我几岁都不会当中撒谎,或者讲前世的故事。
河南林县食管癌高发区,60年代就惊动了周总理
河南林县老早就有确诊的食管癌了
其实我想告诉大家的就是为啥癌症从罕见到少见到常见.
这是什么引起的? 大家必须思考一下. 我主贴里的文章本来就是要抛砖引玉.
lol.
这个年头到处都是坑儿. 不小心就跌进去.
有些是其他病因死亡的,有些甚至是车祸等非健康原因死亡的,无法预料他们带着癌细胞能活多久,也许最终的致死主要原因仍然不是癌症,也许采取健康生活方式,养生得当,战胜癌症,案例很多,本坛就有。