The Gilead trials specifically exclude patients who were on mechanical ventilation at screening. Further, patients who had serious underlying issues, including multiorgan failure, kidney or liver impairment, were similarly left out of the trial.
【 在 cloveara (不帅拿) 的大作中提到: 】 : 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是 severe : ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数 : 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个 : 。股市怎么看？ : https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead- : remdesivir-treatment-clinical-trials-inconclusive/ : The Gilead trials specifically exclude patients who were on mechanical : ventilation at screening. Further, patients who had serious underlying : issues, including multiorgan failure, kidney or liver impairment, were : similarly left out of the trial.
他这个数据和之前的基本一样 based on a back-of-the-envelope analysis combining two studies of the clinical progression of COVID-19, roughly 9 percent of severe cases become critical, and approximately 3 percent of patients with severe symptoms die.
Congressman calls for SEC investigation into leak about possible coronavirus drug By Elizabeth Cohen and Devon M. Sayers, CNN Updated 2:41 PM EDT, Sat April 18, 2020
说明这是股市要涨所以要编个故事，而不是得到消息然后股市才涨。 【 在 cloveara (不帅拿) 的大作中提到: 】 : 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是 severe : ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数 : 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个 : 。股市怎么看？ : https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead- : remdesivir-treatment-clinical-trials-inconclusive/ : The Gilead trials specifically exclude patients who were on mechanical : ventilation at screening. Further, patients who had serious underlying : issues, including multiorgan failure, kidney or liver impairment, were : similarly left out of the trial.
【 在 cloveara (不帅拿) 的大作中提到: 】 : 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是 severe : ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数 : 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个 : 。股市怎么看？ : https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead- : remdesivir-treatment-clinical-trials-inconclusive/ : The Gilead trials specifically exclude patients who were on mechanical : ventilation at screening. Further, patients who had serious underlying : issues, including multiorgan failure, kidney or liver impairment, were : similarly left out of the trial. : ...................
A total of 61 hospitalized patients with severe disease in the U.S., Canada, Europe, and Japan received intravenous remdesivir, but only 53 were evaluated; the rest did not have posttreatment data or had a dosing error. Before receiving remdesivir, patients' median symptom duration was 12 days, 57% were receiving mechanical ventilation, and 8% were on extracorporeal membrane oxygenation (ECMO).
Outcomes at a median of 18 days after receiving the first dose of remdesivir included the following:
Need for oxygen support improved in 68% of the patients.
Of those receiving mechanical ventilation, 57% were extubated.
Three of four people on ECMO stopped receiving it.
At the most recent follow-up date, 47% had been discharged.
Overall mortality was 13% (18% in those receiving mechanical ventilation; 5% in those receiving noninvasive ventilation or oxygen supplementation).
Of the 53 patients, 60% had adverse events, such as elevated liver enzymes, diarrhea, or renal insufficiency.
现在消息满天飞，还有NIH的6只猴子，休斯顿一个trial负责人的谈话都偏重这个是神 药。按说在没有出最终结果情况下，不该轻易发表言论。Gilead 在主页上倒是放了一 封很公正的信，里边列了所以现在进行的trial，并没给出任何预期结果，所以不管药 效如何，基本撇清了自己的责任。 现在总算理解为啥医学类的东西上来都要说no conflict of interest.
【 在 cloveara (不帅拿) 的大作中提到: 】 : 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是 severe : ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数 : 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个 : 。股市怎么看？ : https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead- : remdesivir-treatment-clinical-trials-inconclusive/ : The Gilead trials specifically exclude patients who were on mechanical : ventilation at screening. Further, patients who had serious underlying : issues, including multiorgan failure, kidney or liver impairment, were : similarly left out of the trial.
We have accelerated and expanded production of our investigational COVID-19 treatment and continue to increase supply. Hear from our Chairman CEO on our manufacturing progress and intent to donate supply following potential regulatory authorizations: https://t.co/ZFjeS24XXv. https://t.co/XmDTel51Es
【 在 Gtrader (易交) 的大作中提到: 】 : We have accelerated and expanded production of our investigational COVID- 19 : treatment and continue to increase supply. Hear from our Chairman CEO on our : manufacturing progress and intent to donate supply following potential : regulatory authorizations: https://t.co/ZFjeS24XXv. https://t.co/ XmDTel51Es
【 在 tudou8 (土豆) 的大作中提到: 】 : 你说的是这个实验吧，61个重症病人，4个病人用了ECMO。对68%的病人有效，对60%的 : 病人有副作用。应该说这个药还是有点效果，但肯定不是那些舔货吹嘘的神药，至少现 : 在看不出来。 : https://www.jwatch.org/na51364/2020/04/13/results-compassionate-use- : remdesivir-severe-covid-19 : A total of 61 hospitalized patients with severe disease in the U.S., Canada, : Europe, and Japan received intravenous remdesivir, but only 53 were : evaluated; the rest did not have posttreatment data or had a dosing error. : Before receiving remdesivir, patients' median symptom duration was 12 days, : 57% were receiving mechanical ventilation, and 8% were on extracorporeal : ...................
甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是severe
，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个。股市怎么看？
https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead-
remdesivir-treatment-clinical-trials-inconclusive/
The Gilead trials specifically exclude patients who were on mechanical
ventilation at screening. Further, patients who had serious underlying
issues, including multiorgan failure, kidney or liver impairment, were
similarly left out of the trial.
赞信息灵通。
股市可能这样来看，这消息用过就行了，现在再找下一个，呵呵。
【 在 cloveara (不帅拿) 的大作中提到: 】
: 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是
severe
: ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数
: 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个
: 。股市怎么看？
: https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead-
: remdesivir-treatment-clinical-trials-inconclusive/
: The Gilead trials specifically exclude patients who were on mechanical
: ventilation at screening. Further, patients who had serious underlying
: issues, including multiorgan failure, kidney or liver impairment, were
: similarly left out of the trial.
他这个数据和之前的基本一样
based on a back-of-the-envelope analysis combining two studies of the
clinical progression of COVID-19, roughly 9 percent of severe cases become
critical, and approximately 3 percent of patients with severe symptoms die.
注意这个是在有医疗支持的条件下，如果没有医疗支持。。。
Congressman calls for SEC investigation into leak about possible coronavirus drug
By Elizabeth Cohen and Devon M. Sayers, CNN
Updated 2:41 PM EDT, Sat April 18, 2020
不对吧。我记得说的其中特别提到多少人有基础病，不少人（数字记不得了）有上了
invasive ventilator,还有5个上了ecomo的。
说明这是股市要涨所以要编个故事，而不是得到消息然后股市才涨。
【 在 cloveara (不帅拿) 的大作中提到: 】
: 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是
severe
: ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数
: 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个
: 。股市怎么看？
: https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead-
: remdesivir-treatment-clinical-trials-inconclusive/
: The Gilead trials specifically exclude patients who were on mechanical
: ventilation at screening. Further, patients who had serious underlying
: issues, including multiorgan failure, kidney or liver impairment, were
: similarly left out of the trial.
这个是前一份报告，同样也是比较偏positive的结果，当然也不是双盲的结果。这儿有不少人不愿意看到好的结果，因为死人财没发到，反而做空亏了老本~~~LOL。另外还有不少发帖挣钱的底层穷鬼五毛在搅混水
【 在 libaliu () 的大作中提到: 】
: 不对吧。我记得说的其中特别提到多少人有基础病，不少人（数字记不得了）有上了: invasive ventilator,还有5个上了ecomo的。
属实
【 在 zlm (We will prevail) 的大作中提到: 】
: 这个是前一份报告，同样也是比较偏positive的结果，当然也不是双盲的结果。这儿有
: 不少人不愿意看到好的结果，因为死人财没发到，反而做空亏了老本~~~LOL。另外还有
: 不少发帖挣钱的底层穷鬼五毛在搅混水
是吧是不是太有效了把
【 在 cloveara (不帅拿) 的大作中提到: 】
: 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是
severe
: ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数
: 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个
: 。股市怎么看？
: https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead-
: remdesivir-treatment-clinical-trials-inconclusive/
: The Gilead trials specifically exclude patients who were on mechanical
: ventilation at screening. Further, patients who had serious underlying
: issues, including multiorgan failure, kidney or liver impairment, were
: similarly left out of the trial.
: ...................
你说的是这个实验吧，61个重症病人，4个病人用了ECMO。对68%的病人有效，对60%的
病人有副作用。应该说这个药还是有点效果，但肯定不是那些舔货吹嘘的神药，至少现在看不出来。
https://www.jwatch.org/na51364/2020/04/13/results-compassionate-use-
remdesivir-severe-covid-19
A total of 61 hospitalized patients with severe disease in the U.S., Canada, Europe, and Japan received intravenous remdesivir, but only 53 were
evaluated; the rest did not have posttreatment data or had a dosing error.
Before receiving remdesivir, patients' median symptom duration was 12 days, 57% were receiving mechanical ventilation, and 8% were on extracorporeal
membrane oxygenation (ECMO).
Outcomes at a median of 18 days after receiving the first dose of remdesivir included the following:
Need for oxygen support improved in 68% of the patients.
Of those receiving mechanical ventilation, 57% were extubated.
Three of four people on ECMO stopped receiving it.
At the most recent follow-up date, 47% had been discharged.
Overall mortality was 13% (18% in those receiving mechanical ventilation; 5% in those receiving noninvasive ventilation or oxygen supplementation).
Of the 53 patients, 60% had adverse events, such as elevated liver enzymes, diarrhea, or renal insufficiency.
【 在 libaliu () 的大作中提到: 】
: 不对吧。我记得说的其中特别提到多少人有基础病，不少人（数字记不得了）有上了: invasive ventilator,还有5个上了ecomo的。
现在消息满天飞，还有NIH的6只猴子，休斯顿一个trial负责人的谈话都偏重这个是神
药。按说在没有出最终结果情况下，不该轻易发表言论。Gilead 在主页上倒是放了一
封很公正的信，里边列了所以现在进行的trial，并没给出任何预期结果，所以不管药
效如何，基本撇清了自己的责任。
现在总算理解为啥医学类的东西上来都要说no conflict of interest.
【 在 cloveara (不帅拿) 的大作中提到: 】
: 甚至是confirm之前的数据。关键词，同情用药，没有对照组。而且这个设计是
severe
: ，其实并不是最severe cases，排除了critical condition。在这种情况和之前中国数
: 据其实基本吻合的，并没有意外之处。甚至同样情况下中国没死人，他这里还死了两个
: 。股市怎么看？
: https://www.nationalreview.com/2020/04/coronavirus-pandemic-gilead-
: remdesivir-treatment-clinical-trials-inconclusive/
: The Gilead trials specifically exclude patients who were on mechanical
: ventilation at screening. Further, patients who had serious underlying
: issues, including multiorgan failure, kidney or liver impairment, were
: similarly left out of the trial.
你是怎么变成轮子的 以前玩围棋很正常一个人啊
【 在 ananpig (别瞅 变态辣椒 漫画的●○安安猪) 的大作中提到: 】
: 是吧是不是太有效了把
: https://pbs.twimg.com/media/ET_vvvUUcAAmotP.jpg
: severe
We have accelerated and expanded production of our investigational COVID-19 treatment and continue to increase supply. Hear from our Chairman CEO on our manufacturing progress and intent to donate supply following potential
regulatory authorizations: https://t.co/ZFjeS24XXv. https://t.co/XmDTel51Es
哈哈好可爱
很多人对铲子邪门本质的认识深刻，不等于这些人都是轮子啊
很多人对铲子邪门本质的还没有认识到，也不等于这些人全都是傻子，
——人从无知到觉醒也是要慢慢来的
【 在 wythink ( b) 的大作中提到: 】
: 标 题: Re: Gilead芝加哥数据没有看出显著药效
: 发信站: BBS 未名空间站 (Sun Apr 19 14:59:23 2020, 美东)
:
: 你是怎么变成轮子的 以前玩围棋很正常一个人啊
:
: 【 在 ananpig (别瞅 变态辣椒 漫画的●○安安猪) 的大作中提到: 】
: : 是吧是不是太有效了把
: : https://pbs.twimg.com/media/ET_vvvUUcAAmotP.jpg
: : severe
:
:
:
:
: --
: ☆ 发自 iPhone 买买提 1.24.07
: --
good job
贺诗——
武汉肺炎起猖狂，亿万病毒越土疆。兴亡满目昔胜今，天翻地覆锁城邦。阴差阳错发吹哨，不可沽名萨格尔王。颐使气指传世界，人间正道除祸殃
【 在 Gtrader (易交) 的大作中提到: 】
: We have accelerated and expanded production of our investigational COVID-
19
: treatment and continue to increase supply. Hear from our Chairman CEO on
our
: manufacturing progress and intent to donate supply following potential
: regulatory authorizations: https://t.co/ZFjeS24XXv. https://t.co/
XmDTel51Es
好屎！！！！
赞！ 自己的原创？？
对的。我把这两个搞错了。
但是上面提到的副作用，并不一定是用药导致的。因为不用药的病人也有这种肝肾损害。一个多月前康奈尔大学Weill医学院的医生Matt McCarthy就说过这个问题。见https://twitter.com/DrMattMcCarthy/status/1238939403206221824
【 在 tudou8 (土豆) 的大作中提到: 】
: 你说的是这个实验吧，61个重症病人，4个病人用了ECMO。对68%的病人有效，对60%的
: 病人有副作用。应该说这个药还是有点效果，但肯定不是那些舔货吹嘘的神药，至少现
: 在看不出来。
: https://www.jwatch.org/na51364/2020/04/13/results-compassionate-use-
: remdesivir-severe-covid-19
: A total of 61 hospitalized patients with severe disease in the U.S.,
Canada,
: Europe, and Japan received intravenous remdesivir, but only 53 were
: evaluated; the rest did not have posttreatment data or had a dosing error.
: Before receiving remdesivir, patients' median symptom duration was 12 days,
: 57% were receiving mechanical ventilation, and 8% were on extracorporeal
: ...................
baseline? this was a good run.
估计被迫害了一轮
【 在 wythink ( b) 的大作中提到: 】
: 你是怎么变成轮子的 以前玩围棋很正常一个人啊