临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦了。。。。---“导致没法做全盲”是我个人猜的。 The University of Chicago Medicine recruited 125 people with Covid-19 into Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe disease. All the patients have been treated with daily infusions of remdesivir.
【 在 robertfrost (robertfrost) 的大作中提到: 】 : 标 题: 瑞德西韦太有效了，导致没法做全盲 : 发信站: BBS 未名空间站 (Sat Apr 18 00:29:50 2020, 美东) : : 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦 : 了。。。。---“导致没法做全盲”是我个人猜的。 : The University of Chicago Medicine recruited 125 people with Covid-19 into : Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe : disease. All the patients have been treated with daily infusions of : remdesivir. : : “The best news is that most of our patients have already been discharged, : which is great. We’ve only had two patients perish,” said Kathleen Mullane : , the University of Chicago infectious disease specialist overseeing the : remdesivir studies for the hospital. : : http://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/ : : : : : --
【 在 robertfrost (robertfrost) 的大作中提到: 】 : 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦 : 了。。。。---“导致没法做全盲”是我个人猜的。 : The University of Chicago Medicine recruited 125 people with Covid-19 into : Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe : disease. All the patients have been treated with daily infusions of : remdesivir. : “The best news is that most of our patients have already been discharged, : which is great. We’ve only had two patients perish,” said Kathleen Mullane : , the University of Chicago infectious disease specialist overseeing the : remdesivir studies for the hospital. : ...................
【 在 robertfrost (robertfrost) 的大作中提到: 】 : 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦 : 了。。。。---“导致没法做全盲”是我个人猜的。 : The University of Chicago Medicine recruited 125 people with Covid-19 into : Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe : disease. All the patients have been treated with daily infusions of : remdesivir. : “The best news is that most of our patients have already been discharged, : which is great. We’ve only had two patients perish,” said Kathleen Mullane : , the University of Chicago infectious disease specialist overseeing the : remdesivir studies for the hospital. : ...................
【 在 robertfrost (robertfrost) 的大作中提到: 】 : 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦 : 了。。。。---“导致没法做全盲”是我个人猜的。 : The University of Chicago Medicine recruited 125 people with Covid-19 into : Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe : disease. All the patients have been treated with daily infusions of : remdesivir. : “The best news is that most of our patients have already been discharged, : which is great. We’ve only had two patients perish,” said Kathleen Mullane : , the University of Chicago infectious disease specialist overseeing the : remdesivir studies for the hospital. : ...................
临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦了。。。。---“导致没法做全盲”是我个人猜的。
The University of Chicago Medicine recruited 125 people with Covid-19 into
Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe
disease. All the patients have been treated with daily infusions of
remdesivir.
“The best news is that most of our patients have already been discharged,
which is great. We’ve only had two patients perish,” said Kathleen Mullane, the University of Chicago infectious disease specialist overseeing the
remdesivir studies for the hospital.
http://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/
据说人民的希望recruit重症patients是有附加要求的，比如说肝脏功能正常
如果这是真的， 那本身就有huge bias
不做双盲是拿不到批文的（正常情况下）， 当然不排除FDA受政治压力特批
盹盹盹
【 在 robertfrost (robertfrost) 的大作中提到: 】
: 标 题: 瑞德西韦太有效了，导致没法做全盲
: 发信站: BBS 未名空间站 (Sat Apr 18 00:29:50 2020, 美东)
:
: 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦
: 了。。。。---“导致没法做全盲”是我个人猜的。
: The University of Chicago Medicine recruited 125 people with Covid-19 into
: Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe
: disease. All the patients have been treated with daily infusions of
: remdesivir.
:
: “The best news is that most of our patients have already been discharged,
: which is great. We’ve only had two patients perish,” said Kathleen
Mullane
: , the University of Chicago infectious disease specialist overseeing the
: remdesivir studies for the hospital.
:
: http://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/
:
:
:
:
: --
就这个治愈率，如果将来死人多了还不得赔死？
有 bias 沒關係，就當作用藥的 pre-condition：必須符合這個那個條件才能用此藥。
全盲怎麼做？都快死的人，誰願意吃 placebo？
【 在 wsbioguy2 (postdog) 的大作中提到: 】
: 据说人民的希望recruit重症patients是有附加要求的，比如说肝脏功能正常
: 如果这是真的， 那本身就有huge bias
: 不做双盲是拿不到批文的（正常情况下）， 当然不排除FDA受政治压力特批
: 盹盹盹
: Mullane
这吗深得水
At war time, life first, science second, it's common sense.
全盲实验不是说另一个arm的不吃药，只是按正常流程治疗。再等几天武汉的双盲结果
应该要出来了。看看吧。希望有效。
【 在 robertfrost (robertfrost) 的大作中提到: 】
: 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦
: 了。。。。---“导致没法做全盲”是我个人猜的。
: The University of Chicago Medicine recruited 125 people with Covid-19 into
: Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe
: disease. All the patients have been treated with daily infusions of
: remdesivir.
: “The best news is that most of our patients have already been discharged,
: which is great. We’ve only had two patients perish,” said Kathleen
Mullane
: , the University of Chicago infectious disease specialist overseeing the
: remdesivir studies for the hospital.
: ...................
终止了吧，还能够出来吗？
【 在 DreamTiger (钟爱你一生) 的大作中提到: 】
: 全盲实验不是说另一个arm的不吃药，只是按正常流程治疗。再等几天武汉的双盲结果
: 应该要出来了。看看吧。希望有效。
: Mullane
武汉早就已经没有双盲了，中国说没有重症病人，不做了。
【 在 DreamTiger (钟爱你一生) 的大作中提到: 】
: 全盲实验不是说另一个arm的不吃药，只是按正常流程治疗。再等几天武汉的双盲结果
: 应该要出来了。看看吧。希望有效。
: Mullane
数据很好的说明这药的有效性，粉红和作弊们一直在攻击这个药，也真是没人性了
【 在 robertfrost (robertfrost) 的大作中提到: 】
: 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦
: 了。。。。---“导致没法做全盲”是我个人猜的。
: The University of Chicago Medicine recruited 125 people with Covid-19 into
: Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe
: disease. All the patients have been treated with daily infusions of
: remdesivir.
: “The best news is that most of our patients have already been discharged,
: which is great. We’ve only had two patients perish,” said Kathleen
Mullane
: , the University of Chicago infectious disease specialist overseeing the
: remdesivir studies for the hospital.
: ...................
提前终止，意味着结束了，不是说失败了，该出什么文章还是出什么文章。
【 在 peacemind2 (土豆) 的大作中提到: 】
: 终止了吧，还能够出来吗？
前几天刚终止，按以前的计划，结果应该在一周内会出来。
【 在 robertfrost (robertfrost) 的大作中提到: 】
: 武汉早就已经没有双盲了，中国说没有重症病人，不做了。
看粉红使劲的黑这个药就说明这药效果应该很好
【 在 robertfrost (robertfrost) 的大作中提到: 】
: 临床3期试验，113个重症，只死两个，以后谁愿意去参加全盲实验？都直接要瑞德西韦
: 了。。。。---“导致没法做全盲”是我个人猜的。
: The University of Chicago Medicine recruited 125 people with Covid-19 into
: Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe
: disease. All the patients have been treated with daily infusions of
: remdesivir.
: “The best news is that most of our patients have already been discharged,
: which is great. We’ve only had two patients perish,” said Kathleen
Mullane
: , the University of Chicago infectious disease specialist overseeing the
: remdesivir studies for the hospital.
: ...................
深切怀疑武汉实际上是瑞德希韦药全不翼而飞，被移用在特殊病人身上，所以才没办法搞双盲试验，什么抢不到病人，不过是借口罢了
不会的。实验应该做完了。疗程又短，药物肯定是充足的
【 在 Adrianne (阿德里安妮) 的大作中提到: 】
: 深切怀疑武汉实际上是瑞德希韦药全不翼而飞，被移用在特殊病人身上，所以才没办法
: 搞双盲试验，什么抢不到病人，不过是借口罢了
快转笑话版。
【 在 Adrianne (阿德里安妮) 的大作中提到: 】
: 深切怀疑武汉实际上是瑞德希韦药全不翼而飞，被移用在特殊病人身上，所以才没办法
: 搞双盲试验，什么抢不到病人，不过是借口罢了