揭开伟哥神药PAXLOVID (PF-07321332; ritonavir)的面纱 (转载)

d
dragonfly
楼主 (未名空间)

【 以下文字转载自 Military 讨论区 】
发信人: dragonfly (五星旗插遍太阳系), 信区: Military
标 题: 揭开伟哥神药PAXLOVID (PF-07321332; ritonavir)的面纱
发信站: BBS 未名空间站 (Fri Nov 5 15:01:42 2021, 美东)

洛匹那韋/利托那韋(Lopinavir/ritonavir (LPV/r);商品名:克力芝
从里面拿出一种成分ritonavir,就成了89%效力的神药。
再复习一下克力芝的效果:
Our previous use of chloroquine to treat patients with COVID-19 infection
showed an improvement in more throat-swab nucleic-acid results (5/10) than
the use of lopinavir/ritonavir.
效果还不如氯喹。https://pubmed.ncbi.nlm.nih.gov/32641091/
it did not lead to any difference in the duration of hospitalization and may lead to an increase in the number of total adverse effects. The overall
certainty of the evidence was low or very low.
有效性证据很低,增加副作用,不缩短住院时间。https://pubmed.ncbi.nlm.nih.gov/32678815/

怎么到了伟哥手里,摇身一变就成了大仙?真是人有多大胆,药有多大效。