A little-known Chinese company made a drug that beat the world’s biggest-selling medicine CNN — China’s DeepSeek shocked the world by delivering unexpected innovation at an unbelievable price. But this disruptive trend isn’t confined to Big Tech: it has been quietly happening in the pharmaceutical sector. In September, Akeso, a little-known Chinese biotech company founded nearly a decade ago shook up the biotech sector with its new lung cancer drug. Ivonescimab, the new drug, was found in a trial conducted in China to have bested Keytruda, the blockbuster medication developed by Merck that has raked in more than $130 billion in sales for the American behemoth that has dominated cancer treatment.
CNN — China’s DeepSeek shocked the world by delivering unexpected innovation at an unbelievable price. But this disruptive trend isn’t confined to Big Tech: it has been quietly happening in the pharmaceutical sector. In September, Akeso, a little-known Chinese biotech company founded nearly a decade ago shook up the biotech sector with its new lung cancer drug.
Ivonescimab, the new drug, was found in a trial conducted in China to have bested Keytruda, the blockbuster medication developed by Merck that has raked in more than $130 billion in sales for the American behemoth that has dominated cancer treatment.
美国鼓吹天才的leadership，注定失败
目前看，中国生物制药需要的人才是，熟悉FDA流程的，可以帮助大陆药在美国过FDA.
确实不少做生物的海龟。
俺个人认为， leadership 是做出来的，而不是吹出来的， leadership 是结果，而不是可操作参数
二战乃至二战后，美国的研发，生产 ，组织能力， 比现在强的多，结果是成了世界leader
现在连组织阿波罗计划的能力都没有了， 当年航母战舰跟下饺子一样，现在任何一个ppt 以外的产品都要等几年。。。。。
不了解制药的就别想当然了
国内小分子制药才刚热乎， 生物制药还差得远， 不论研， 发， 还是生产，申报，乃至clinical trial，质量体系，合规操作等 都还在起步阶段， 更别提 啥熟悉FDA流程的。。。。 这种人在美国都缺 至于大陆药过美国FDA， 这个事情有多个因素决定，不是说来个养鸡专业户的的人就能让小狗下蛋的
FDA不是正好在裁员吗。虽然咱们不都是业内人士，但楼主贴了新闻source，也不可能完全是空穴来风。
FDA 是在裁员，但这不意味着通过BLA审批会容易， 实际上99%的可能是审批会更拖延 楼上说的这个bispecific antibody 比 keytruda efficacy 高那是非常正常的事情, 这俩是同一个治疗类别，但不同机理结构的药物。 在bispecific这个类别中， 这个是个成功研发的例子， 这个类别中FDA 批了好几个了，后面还会有更多， 在抗体药物的发展中，这个将是一大类。