反复发作的UTI可能原因是biofilm。 Biofilm形成后会对里面的细菌起保护作用,难以被清除。可能需要更大剂量更长时间抗生素来彻底清除 Treating urinary tract infections (UTIs) complicated by biofilms requires a multifaceted approach, as biofilms protect bacteria from antibiotics and immune responses. Here's an overview of potential strategies: 1. Antibiotic TherapyExtended Courses of Antibiotics: Longer or higher doses of antibiotics may be required to penetrate the biofilm and eradicate the infection. Biofilm-Disrupting Antibiotics: Some antibiotics, such as fosfomycin and nitrofurantoin, have shown efficacy in disrupting biofilms in UTIs. Combination Therapy: Using multiple antibiotics with different mechanisms of action can improve outcomes by targeting biofilm-forming bacteria more effectively. 2. Adjunctive TherapiesAntibiofilm Agents: Substances like EDTA, N-acetylcysteine, and certain enzymes (e.g., DNase) can break down the biofilm matrix, improving antibiotic penetration. Natural Compounds: Plant-based compounds such as cranberry extract (rich in proanthocyanidins), D-mannose, and curcumin have been studied for their antibiofilm properties. 3. Preventive MeasuresHygiene and Hydration: Regularly emptying the bladder and maintaining proper hygiene can help reduce bacterial load. Catheter Management: If a catheter is in use, replacing it regularly and using coated or specialized catheters can reduce biofilm formation. 4. Non-Antibiotic TreatmentsPhage Therapy: Bacteriophages target specific bacterial strains and can help break down biofilms. Silver Nanoparticles: These have antimicrobial and antibiofilm properties but are still under investigation. 5. Advanced InterventionsLaser or Ultrasound: Low-energy laser or ultrasound therapies can disrupt biofilms and enhance antibiotic effectiveness. Surgical Intervention: In severe cases, removing infected devices or tissues may be necessary. 6. ImmunotherapyVaccines and Immunomodulators: Ongoing research is exploring the development of vaccines or immune system boosters to combat biofilm-associated infections. Consultation and Monitoring Always consult a healthcare provider for: Proper Diagnosis: Laboratory tests (urine cultures, imaging, etc.) to identify biofilm-associated bacteria. Tailored Treatment: Based on bacterial strain, antibiotic susceptibility, and individual health conditions. Regular Monitoring: To ensure the infection is fully resolved and prevent recurrence. Persistent UTIs with biofilms can be challenging to treat, but advancements in therapies and combined approaches are improving outcomes.
UTI蛮多次的了。以前的症状都是半天就疼得不得了。但是这次症状不太一样。不是很严重。两天了尿尿偶尔一点点疼。
现在验过尿了确定有感染。但是症状不严重的话不吃抗生素会自己好吗?我的肠胃道被抗生素弄得很糟糕。能不吃就不想吃了。
多次感染可考虑药敏
要是症状很严重,我根本等不到第二天。这点小毛病叫我去emergency 去了也要等半天。哎。
然后想起goodrx可以开药。赶紧上去。结果也是大晚上的,线上护士回复很晚。等拿到药方已经半夜了。一个24小时的药房蛮远的。症状不厉害就算了。
今天起床还是不是很严重。不管了。先拿了goodrx的药再说。查了下urgent care又所有的appointment都满了。好不容易找了个virtual visit。开了验尿单。拿到化验结果和药已经下午了。
还有个槽点。goodrx开的药Walgreens拿的。17块多保险报了五毛。医院开的Cvs拿的药35块多我自己出了五毛。怎么这么乱七八糟的。
https://www.amazon.com/dp/B0018SGX6I?ref=nb_sb_ss_w_as-reorder_k0_1_3&=&crid=R0BLCGVC57O0&sprefix=azo&th=1 这个很管用,吃了之后不会疼
反复发作的UTI可能原因是biofilm。 Biofilm形成后会对里面的细菌起保护作用,难以被清除。可能需要更大剂量更长时间抗生素来彻底清除
Treating urinary tract infections (UTIs) complicated by biofilms requires a multifaceted approach, as biofilms protect bacteria from antibiotics and immune responses. Here's an overview of potential strategies: 1. Antibiotic Therapy Extended Courses of Antibiotics: Longer or higher doses of antibiotics may be required to penetrate the biofilm and eradicate the infection. Biofilm-Disrupting Antibiotics: Some antibiotics, such as fosfomycin and nitrofurantoin, have shown efficacy in disrupting biofilms in UTIs. Combination Therapy: Using multiple antibiotics with different mechanisms of action can improve outcomes by targeting biofilm-forming bacteria more effectively. 2. Adjunctive Therapies Antibiofilm Agents: Substances like EDTA, N-acetylcysteine, and certain enzymes (e.g., DNase) can break down the biofilm matrix, improving antibiotic penetration. Natural Compounds: Plant-based compounds such as cranberry extract (rich in proanthocyanidins), D-mannose, and curcumin have been studied for their antibiofilm properties. 3. Preventive Measures Hygiene and Hydration: Regularly emptying the bladder and maintaining proper hygiene can help reduce bacterial load. Catheter Management: If a catheter is in use, replacing it regularly and using coated or specialized catheters can reduce biofilm formation. 4. Non-Antibiotic Treatments Phage Therapy: Bacteriophages target specific bacterial strains and can help break down biofilms. Silver Nanoparticles: These have antimicrobial and antibiofilm properties but are still under investigation. 5. Advanced Interventions Laser or Ultrasound: Low-energy laser or ultrasound therapies can disrupt biofilms and enhance antibiotic effectiveness. Surgical Intervention: In severe cases, removing infected devices or tissues may be necessary. 6. Immunotherapy Vaccines and Immunomodulators: Ongoing research is exploring the development of vaccines or immune system boosters to combat biofilm-associated infections. Consultation and Monitoring Always consult a healthcare provider for: Proper Diagnosis: Laboratory tests (urine cultures, imaging, etc.) to identify biofilm-associated bacteria. Tailored Treatment: Based on bacterial strain, antibiotic susceptibility, and individual health conditions. Regular Monitoring: To ensure the infection is fully resolved and prevent recurrence. Persistent UTIs with biofilms can be challenging to treat, but advancements in therapies and combined approaches are improving outcomes.
谢谢。已经很注意了,一不小心又发作。也是很怕以后频繁发生。
我前几次严重的时候吃这个也不行。小便跟刀割一样
不吃抗生素也可以自己好的是吗
谢谢。蔓越莓素有吃。D mannose不知道呢。谢谢介绍
D mannose 是粉,一勺粉配一杯水搅开然后喝,粉和水不用那么严格多少定量,反正就是喝下去就行了,严重时可以多喝几次,反正你网上看一下它的介绍,这是医生推荐的。
虽然我作为所难不应该参与讨论,但这个只有止痛作用,没有抑制细菌的功能。考虑用下面这种有抑菌功能的。
蔓越莓汁了解一下