回复 1楼 的帖子 哇，不给辐射式筛查那就自己去做个血检吧，推荐galleri. 听Peter Aria的podcast,貌似late stage癌症（限定种类吧）还是能探测出来的。 https://my.grail.com/ The Galleri test is available by prescription only. Request the test online. Request the test online through an independent telemedicine provider and select “I have a Galleri Key.” Enter the Galleri Key to receive $50 off*: 24GIFT50 Your test must be ordered by December 31, 2024, to receive $50 off.*
When the body says no 里面解释了，抽烟只是一个风险因素不是全部，基因也只是一方面，自然环境也是一方面但以前烧柴通风也不好也没这么多呀，特别是社会环境人际关系亲密关系，癌症和其他慢性病的发展很多与被压抑的情绪有关，always nice, always think of others, 把自己的感受压抑起来，时间长了这个不自知的压力会把免疫系统搞坏各种慢性病癌症更容易发生。那些朋友是都很nice positive 的吗。亚裔女性来到美国，整体是unheard, 社会家庭的环境对心理生理压力不小的，而且很多时候人根本意识不到
是这个基因，我之前也读到过。身边也有好几例非吸烟者，有症状后查出肺癌晚期走的。 但是美国治疗指南不筛查这个基因，只有针对老烟枪的筛查。 自费的话肯定有地方查这个基因。 Comprehensive biomarker testing for NSCLC treatment | BiomarkerTesting.com 下面摘自WEBMED。 Research: EGFR-Mutated Lung Cancer Among Asian Women Studies show that more than half of Asian American women diagnosed with lung cancer did not previously smoke. Among them, women of Chinese descent have a much higher risk. Up to 8 out of 10 women diagnosed with lung cancer have never smoked before. And compared to other ethnic groups, Asian American women who have never smoked are nearly twice as likely to get lung cancer. “It's the leading cause of cancer death for this population,” says Rotow. So what’s the link? In one lung cancer screening study presented by Elaine Shum, MD, from New York University at the 2023 ASCO annual meeting, over 200 Asian women under 40 who have little to no history of smoking were given three annual CT chest scans. That’s an imaging test that allows doctors to take a closer look at your lungs. Shum found that nearly 2% of the young, nonsmoking population of Asian women had lung cancer. “All of the lung cancers they identified were EGFR mutated and were able to go on to receive adjuvant EGFR-targeted therapy,” says Rotow. Adjuvant targeted therapy is a type of additional or follow-up treatment given after you’ve had your main treatment plan such as surgery or chemotherapy. These therapies target and wipe out the cancer cells that might have been left behind after your main treatment. This will lower the odds of your cancer coming back.
不抽烟的东亚女性得肺癌的多和自身基因有关。 Early diagnosis of EGFR-mutated non-small cell lung cancer (NSCLC) involves a combination of clinical assessment, imaging studies, and molecular testing. Here’s a step-by-step guide to facilitate early detection: 1. Recognize Symptoms and Risk Factors EGFR-mutated NSCLC is more common in non-smokers, women, and individuals of East Asian descent. Symptoms to watch for include: Persistent cough Shortness of breath Unexplained weight loss Fatigue Chest pain Coughing up blood (hemoptysis) If you have risk factors or symptoms, consult a healthcare provider promptly. 2. Initial Diagnostic Workup Imaging Studies: Chest X-rays or CT scans can reveal suspicious lung nodules or masses. Low-dose CT scans: Recommended for high-risk individuals, such as those with a significant smoking history or family history of lung cancer. 3. Tissue or Liquid Biopsy Tissue Biopsy: A sample of lung tissue is obtained through methods like bronchoscopy, fine-needle aspiration, or surgical biopsy. Liquid Biopsy: A less invasive option that detects tumor-derived DNA in the blood (circulating tumor DNA or ctDNA). Both methods can confirm cancer and provide material for genetic testing. 4. Molecular Testing for EGFR Mutations Molecular testing is critical to detect EGFR mutations (e.g., exon 19 deletions, exon 21 L858R point mutations). Testing can be performed on biopsy tissue or blood (for liquid biopsy). This step ensures the cancer is EGFR-mutated and helps guide targeted therapy decisions. 5. Screening in High-Risk Groups For those at higher risk (e.g., due to family history or demographic factors), regular screenings can lead to earlier detection: Annual low-dose CT scans Genetic counseling and testing if there’s a family history of lung cancer. 6. Consult with Specialists Seek care from a pulmonologist, oncologist, or cancer specialist familiar with lung cancer diagnosis and treatment. Why Early Diagnosis Matters: Targeted Therapy: EGFR-mutated NSCLC responds well to EGFR tyrosine kinase inhibitors (TKIs), such as osimertinib. Better Prognosis: Early-stage diagnosis improves the likelihood of effective treatment and prolonged survival. If you suspect any symptoms or have risk factors, don't delay consulting a medical professional!
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你是个什么神经病啊？觉得自己一辈子都在保险箱里吗？真是有毛病。
是一种基因突变
不少女性肺癌患者是从来不进厨房做饭的
是的，我也听不少人说都是是新冠病毒导致的
🛋️ 沙发板凳
多发5mm实性结节。 主动脉及冠脉硬化。 甲状腺密度不均。 肝内片状低密度影。
病人没有啥自己感觉的症状， 咋查出来这么多东西啊？
中国菜油烟大，这几个是不是家里做饭的主力？
granite？石英呢
这样无法解释生活在同一个房子里的成年同龄男性却没事。
+1. 二手烟吸多了尤其是胎儿时期和幼儿时期
国内很多人根本不注意尤其是三四十年前
对啊，有关于中餐的厨师这方面的研究吗？
对油烟这项存疑，虽然没数据，比如父母和祖父母那代人，他们炒菜的条件比不上现在，连抽油烟机都没有，基本没听说过什么人不抽烟就得肺癌了，近年来听说的中青年的例子越来越多，我觉得国内有可能跟空气污染相关，日积月累，美国是因为什么就不知道了，甚至听说过平时不做饭，也不吸烟的人的肺癌
这个亚裔女性无任何家族史无不良嗜好但是肺癌的案例好多，前段时间有发文章专门研究这个原因的，只是说亚裔女性肺癌增长率远高于其他族裔，原因也没说出个所以然来。似乎乳腺癌发病率也升高的很明显。这个亚裔女性癌症高发率真的值得研究看看。
是不是因为亚裔女性为孩子家里等等等等操不完的心。各种比来比去+内卷导致的，哈哈哈。
好象是在美国的亚裔女性更容易得癌症, 在中国不知道是不是一样结果？
文章是欧美这边的，好像只比较在美国各个族裔女性的癌症发生率，说亚裔明显的升高远高于其他族裔，并没有提中国的。同一个国家里的找不到明显原因，基因就是我能想到的主要原因了。如果在美国和中国的不一样，可能是饮食环境等等，变量更大。更早以前有文章说过以前中国的女性乳癌发病率比美国的女性低，但是移居美国的亚裔女性乳癌发病率就升高到美国平均水平了。当时归纳的原因是饮食变化。现在在做这个研究的话，可能结果和当年不同了，因为饮食结构国内早就向欧美靠齐了。
内卷or生活压力大，不应该导致肺癌吧？
我觉得一个可能是清洁剂？认识两个五十出头走的完全没有家庭遗传生活习惯很健康的都是护士。大量接触清洁剂。
这个会不会是因为中美两国，多年前的医疗资源差别太大？多年前国内很少人做mammogram吧，更别说广大农村了。
中国的话，只能提供亚裔的数据，不知道相比以前是不是也大幅上升。不过有一点中国体检CT扫描比较多，很多肺小结节的病例都是体检查出来的，肺癌筛查阳性明显增高。这么算的话，国内男女肺癌发生率都应该上升，尤其是如果早早期，早期这个stage特别高的话，这个升高是新检查手段发现了以前没发现的病例，和发病率没啥关系。美国这边是光亚裔女性大幅升高，其他族裔女性都相对平稳。不知道亚裔这个数据里哪个stage的多，如果也是早期早早期难道是国内体检出来到美国治疗导致这边数据变化的么，哈哈哈那就搞笑了。
这个是明显家族史。
美国自费三百刀也能做，比机票便宜
质量如何啊？
当然会。知道些实例！
哇，不给辐射式筛查那就自己去做个血检吧，推荐galleri. 听Peter Aria的podcast,貌似late stage癌症（限定种类吧）还是能探测出来的。
https://my.grail.com/
The Galleri test is available by prescription only.
Request the test online. Request the test online through an independent telemedicine provider and select “I have a Galleri Key.” Enter the Galleri Key to receive $50 off*: 24GIFT50
Your test must be ordered by December 31, 2024, to receive $50 off.*
我都有，确实没感觉啊。所以国内目前滥用检查也有好处，及早发现。当然医保不持续是另一个问题了
回国的话，胃肠镜和肺都可以安排做一下，自费也没几个钱，普通三甲就可以做，也不太需要找关系，基本质量有保证。有时间的话尽量别去私立的体检机构，有夸大问题的嫌疑，会吓坏自己。
有可能吧。随便想一下， 清洁剂里有大量表面活性剂，吸入会改变呼吸道上皮细胞的通透性。那样清洁剂里面其他对人体有害的物质更容易为细胞所吸收。也或者清洁剂对细胞造成伤害，导致炎症反应 -- 是癌变的一个诱因。
那日常清洁估计只能大量依靠小苏打和白醋了，然后打扫卫生时候戴口罩和手套，减轻风险。
怎么笑得出来？神经
你的意思是，电磁炉，其实比烧gas的炉子对健康好，因为没有“燃烧后产生的废气”？
那个容易得肺癌的女人 平时就是林黛玉那样的性格想不开的 不管当着人还是背着人凄凄惨惨戚戚自悯自怜 多去检查多去肺部造影 这个情绪的影响比什么做饭抽烟二手烟下手狠
是的。我认识一个朋友，是科学家，他家刚装修完厨房，然后他审稿一个PROPOSAL，讲的就是这个事。结果厨房没咋用，直接买了一个100块的电磁炉用--就是我们日常吃火锅的那种。幸好家庭人口少，够用了。
为什么猜测氡气，现在装一个除氡气装置很容易吧。
我以前一直以为，女性心情抑郁，容易得乳腺癌，而不是肺癌。
能筛查出哪些疾病？怎么收费呀？
跟心理这个没关系，国内有单位的都是年度体检，体检项目基本都有这项。新冠后很多人都查出来结节，这都是客观事实。而且一般持续做的话，每年会有对比，不发展就没事。
美国因为医保不批，没事不给做，导致有些人一发现就是晚期了。你改变不了制度，但回国顺便做一个放心
对啊，现在人买房都会检测radon，数值高装一个mitigation就可以了
尽量少用喷雾的那种吧。可以用挤压式的清洁剂。
话说有一次我用一种强力的喷雾清洁剂，喷完之后觉得很呛，气管不舒服。 后来再用就是戴口罩。一个很普通的外科口罩，就可以隔绝掉大部分的气溶胶。
这个在哪里查?
确实。不过我准备研究一下怎么比较方便使用小苏打和白醋了，感觉长期用洗碗机的那个清洁剂对肠胃也不太好。真是各种便利都带来隐性副作用了
在爆炒、油炸等烹饪过程中，食用油和食物会产生大量油烟。而油烟中有超过200多种有害气体，
包括多环芳烃、醛类、丁二烯等，它们都对健康有很大影响，具有致癌性和治突变性，长期与油烟接触是非吸烟女性罹患肺癌的重要危险因素之一。
研究者曾经进行过相关调查，结果发现在不吸烟的女性群体中，和少烟烹饪或者无烟烹饪的人相比，长期接触炒菜油烟的人肺癌的发生风险会提高3.79倍。
此外，长期接触油烟还会增加高血压、动脉粥样硬化、肥胖的风险，同时还会损伤皮肤健康，加速皮肤衰老。”
每个人个体不一样 每个人身体软肋不一样 每个人思维模式不一样 女人本来就是情绪多想得多 然后又想当然的认为丈夫应该帮你排解 丈夫如果不帮助排解 情绪更坏想得更多永远不能排解 乳腺问题多是女人跟老公之间的胜负欲 肺癌多是跟任何人之间的情绪不稳定 污染肯定有关联 但是忽略情绪就把一个重要因素错过了
大厨都是男的身体好，餐厅后厨的抽风设备也好，功率大。
x ray别做了白吃射线
对，所以准备明年回国去检查。
对美国的医疗体系非常不满。。。
是这个基因，我之前也读到过。身边也有好几例非吸烟者，有症状后查出肺癌晚期走的。 但是美国治疗指南不筛查这个基因，只有针对老烟枪的筛查。 自费的话肯定有地方查这个基因。 Comprehensive biomarker testing for NSCLC treatment | BiomarkerTesting.com
下面摘自WEBMED。
Research: EGFR-Mutated Lung Cancer Among Asian Women Studies show that more than half of Asian American women diagnosed with lung cancer did not previously smoke. Among them, women of Chinese descent have a much higher risk. Up to 8 out of 10 women diagnosed with lung cancer have never smoked before. And compared to other ethnic groups, Asian American women who have never smoked are nearly twice as likely to get lung cancer. “It's the leading cause of cancer death for this population,” says Rotow. So what’s the link? In one lung cancer screening study presented by Elaine Shum, MD, from New York University at the 2023 ASCO annual meeting, over 200 Asian women under 40 who have little to no history of smoking were given three annual CT chest scans. That’s an imaging test that allows doctors to take a closer look at your lungs. Shum found that nearly 2% of the young, nonsmoking population of Asian women had lung cancer. “All of the lung cancers they identified were EGFR mutated and were able to go on to receive adjuvant EGFR-targeted therapy,” says Rotow. Adjuvant targeted therapy is a type of additional or follow-up treatment given after you’ve had your main treatment plan such as surgery or chemotherapy. These therapies target and wipe out the cancer cells that might have been left behind after your main treatment. This will lower the odds of your cancer coming back.
竟然事前都没有症状
如果血检可以，那这边能要求做吗
等有症状，肺癌基本上是晚期。
事先毫无征兆。她家是自费做的，不是通过医保。做的初衷是支持朋友一个公司的服务，这个服务就是血检测癌症指标（？）我也不是100%清楚，因为当时电话里聊的，没好意思问那么细，大概这个意思吧。
你如果保险很好，你可以口述夸大症状，试试看能不能批。
https://radiologyassist.com/
美国自费是300刀的事吗，看医生开单子收一次费，做CT检查收一次，用场地也收一笔，医生读片子再收一次
感谢 收藏了。查了一下我周边的 真的$160 太可以了。本来以为我周边会贵一些。 我家多年是high deductible的医疗保险，需要这些自费的资源咔咔。以后呀，着急就自费做，不着急就回国做。我去年回国CT好像是200多还是300块人民币，但没问是不是low dose汗
Early diagnosis of EGFR-mutated non-small cell lung cancer (NSCLC) involves a combination of clinical assessment, imaging studies, and molecular testing. Here’s a step-by-step guide to facilitate early detection:
1. Recognize Symptoms and Risk Factors EGFR-mutated NSCLC is more common in non-smokers, women, and individuals of East Asian descent. Symptoms to watch for include:
Persistent cough Shortness of breath Unexplained weight loss Fatigue Chest pain Coughing up blood (hemoptysis) If you have risk factors or symptoms, consult a healthcare provider promptly.
2. Initial Diagnostic Workup Imaging Studies: Chest X-rays or CT scans can reveal suspicious lung nodules or masses. Low-dose CT scans: Recommended for high-risk individuals, such as those with a significant smoking history or family history of lung cancer. 3. Tissue or Liquid Biopsy Tissue Biopsy: A sample of lung tissue is obtained through methods like bronchoscopy, fine-needle aspiration, or surgical biopsy. Liquid Biopsy: A less invasive option that detects tumor-derived DNA in the blood (circulating tumor DNA or ctDNA). Both methods can confirm cancer and provide material for genetic testing.
4. Molecular Testing for EGFR Mutations Molecular testing is critical to detect EGFR mutations (e.g., exon 19 deletions, exon 21 L858R point mutations). Testing can be performed on biopsy tissue or blood (for liquid biopsy). This step ensures the cancer is EGFR-mutated and helps guide targeted therapy decisions.
5. Screening in High-Risk Groups For those at higher risk (e.g., due to family history or demographic factors), regular screenings can lead to earlier detection:
Annual low-dose CT scans Genetic counseling and testing if there’s a family history of lung cancer.
6. Consult with Specialists Seek care from a pulmonologist, oncologist, or cancer specialist familiar with lung cancer diagnosis and treatment.
Why Early Diagnosis Matters: Targeted Therapy: EGFR-mutated NSCLC responds well to EGFR tyrosine kinase inhibitors (TKIs), such as osimertinib. Better Prognosis: Early-stage diagnosis improves the likelihood of effective treatment and prolonged survival. If you suspect any symptoms or have risk factors, don't delay consulting a medical professional!
血检 xray都没用 只有CT能早筛选
我印象中好像有研究说加州的亚裔乳腺癌发病率较高，水质可能是个因素。
不过我认识的五个癌症去世的只有一个在加州，他们的职业是医生，护士，和大学科研人员，压力普遍较大，而且其中两个夫妻和家庭关系长期紧张。
还认识两个女性一个在四十出头得了乳腺癌，另一个刚五十岁，也是乳腺癌。一个是医生，一个是大学科研小老板，家里都没有遗传，父母身体都很健康。但这两个女性的共同点都是夫妻关系和父母关系一直不好，只要一提父母就会立刻大哭，走不出来。哎。
国内乳腺癌都翻倍了 20多 30多得乳腺癌的比比皆是，国内这几年肺结节 肺癌的也多 很多人觉得是新冠 或者疫苗的问题
这个怎么检测 自己买仪器吗
自己都没有任何症状吗
这边每年体检医生给查一个癌症指标的，你下次问问医生，反正我的医生每年都给查。
做inspection的公司可以测这个。也可以买一个仪器放家里，这样可以随时监测。
我们老东家一女员工，硕士毕业工作不久，查出不到1cm的节，让1年跟踪，不到10个月恶化，提前查出直接进四期。然后坚持了三年多，30岁的样子肺癌去世。
美国的医疗保险制度下，肺癌这种根本没有prescreening. 只有年龄足够大（比如50岁+）的一天几包烟的老烟鬼才可能允许screen,就这样UHC等保险公司还不给你/拖着prior authorization
一直好奇这个问题，但是好像目前没有看到这方面的study,倒是看到中餐师傅很多有颈椎各方面的问题。
是的。我认识的都是很少做饭的国内女性得肺癌。我觉得主要是二手烟和空气污染。癌症development要很长时间，过去的二三十年里国内空气污染挺严重的，虽然现在有很大改善。
It's at least partly due to early screening
所以回国最重要的是全身大检查，特别是美国没病不给做的MRI一类。
啊很有可能！！
我试着用了这个网站make an appointment，需要提供provider referral，是要PCP的referral?
这个很好啊 谢谢
跟便秘的关系是？
老龄化严重+长寿