淋巴转移是不是不归为转移？我这么说是因为乳腺癌如果淋巴转移不属于metastasis. 是否转移淋巴、然后淋巴节有一个还是两个都是grade ii. 如果淋巴节多那可能三级了，但是如果真的转移其他器官了就是grade iv了。所以，淋巴节转移也可能是grade ii. 别查了。帮着她转移注意力，管管孩子，做点儿好吃的。带她去咖啡馆。这是我闺蜜为我做的，我觉得有用。我不需要她帮我查资料。我也不想和她讨论病情、太痛苦。不想我闺蜜为我难受。让她为我做她能做的，她就好过一点儿。我也好过一点儿。my two cents from the other side.
随手找了一篇，省的有人说我胡说： https://pubmed.ncbi.nlm.nih.gov/37175509/ Some viruses are known to be associated with the onset of specific cancers. These microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer cells by modulating the central metabolic pathways or hampering genomic integrity mechanisms, consequently inhibiting the apoptotic machinery and/or enhancing cell proliferation. Seven oncogenic viruses are known to promote tumorigenesis in humans: human papillomavirus (HPV), hepatitis B and C viruses (HBV, HCV), Epstein-Barr virus (EBV), human T-cell leukemia virus 1 (HTLV-1), Kaposi sarcoma-associated herpesvirus (KSHV), and Merkel cell polyomavirus (MCPyV). Recent research indicates that SARS-CoV-2 infection and COVID-19 progression may predispose recovered patients to cancer onset and accelerate cancer development. This hypothesis is based on the growing evidence regarding the ability of SARS-CoV-2 to modulate oncogenic pathways, promoting chronic low-grade inflammation and causing tissue damage. Herein, we summarize the main relationships known to date between virus infection and cancer, providing a summary of the proposed biochemical mechanisms behind the cellular transformation. Mechanistically, DNA viruses (such as HPV, HBV, EBV, and MCPyV) encode their virus oncogenes. In contrast, RNA viruses (like HCV, HTLV-1) may encode oncogenes or trigger host oncogenes through cis-/-trans activation leading to different types of cancer. As for SARS-CoV-2, its role as an oncogenic virus seems to occur through the inhibition of oncosuppressors or controlling the metabolic and autophagy pathways in the infected cells. However, these effects could be significant in particular scenarios like those linked to severe COVID-19 or long COVID. On the other hand, looking at the SARS-CoV-2─cancer relationship from an opposite perspective, oncolytic effects and anti-tumor immune response were triggered by SARS-CoV-2 infection in some cases. In summary, our work aims to recall comprehensive attention from the scientific community to elucidate the effects of SARS-CoV-2 and, more in general, β-coronavirus infection on cancer susceptibility for cancer prevention or supporting therapeutic approaches.
如题。闺蜜确诊肺腺癌，术前几次检查都说是早期，肿瘤不大1.8-2cm。医生说微创手术后不用后续治疗 ，说是早期癌症不会影响寿命。没想到术后病理出来，肿瘤大小4 cm, 医生说没有转移，根据肿瘤大小为依据，判断应该是2a 或者2b，要安排靶向治疗（ROS1型）。闺蜜一下子懵了，俩娃儿，小的才8岁。这几天她受打击不小，情绪低落，尤其是看到复发率和5年生存率数据都不乐观。我也有些焦虑了，一有空就上网查信息。我就想找到让她重新振作起来的数据，给她打气，倒是找到一些，但不能把整个文章给她看，只能摘取最好的数据和结论给她看。有问题我不太明白，2a 应该是局部肿瘤，2b 是不是有肺内淋巴结转移了，为什么医生说没有转移呢。这些应该病理报告上有写吧，但我不敢让闺蜜去要病理w报告，怕她知道太多胡思乱想。另外，肿瘤大小出入很大，这正常吗？ 知道华人上有很多懂医的姐妹，请帮忙分析一下闺蜜的情况，预后如何，治愈的几率有多大；靶向药耐药后是否有很多其它靶向药有效。还有，我怎么帮她振作起来积极面对。谢谢。
这是闺蜜还是爱人？医院肯定提供病理报告，你闺蜜自己和她家里人不会去看病理报告？
别查了。帮着她转移注意力，管管孩子，做点儿好吃的。带她去咖啡馆。这是我闺蜜为我做的，我觉得有用。我不需要她帮我查资料。我也不想和她讨论病情、太痛苦。不想我闺蜜为我难受。让她为我做她能做的，她就好过一点儿。我也好过一点儿。my two cents from the other side.
其实我没看懂闺蜜拿不拿报告还要lz让，难道医生不给闺蜜吗？闺蜜老公也不懂？
我也想问这个，平时炒菜多么
https://pubmed.ncbi.nlm.nih.gov/37175509/
Some viruses are known to be associated with the onset of specific cancers. These microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer cells by modulating the central metabolic pathways or hampering genomic integrity mechanisms, consequently inhibiting the apoptotic machinery and/or enhancing cell proliferation. Seven oncogenic viruses are known to promote tumorigenesis in humans: human papillomavirus (HPV), hepatitis B and C viruses (HBV, HCV), Epstein-Barr virus (EBV), human T-cell leukemia virus 1 (HTLV-1), Kaposi sarcoma-associated herpesvirus (KSHV), and Merkel cell polyomavirus (MCPyV). Recent research indicates that SARS-CoV-2 infection and COVID-19 progression may predispose recovered patients to cancer onset and accelerate cancer development. This hypothesis is based on the growing evidence regarding the ability of SARS-CoV-2 to modulate oncogenic pathways, promoting chronic low-grade inflammation and causing tissue damage. Herein, we summarize the main relationships known to date between virus infection and cancer, providing a summary of the proposed biochemical mechanisms behind the cellular transformation. Mechanistically, DNA viruses (such as HPV, HBV, EBV, and MCPyV) encode their virus oncogenes. In contrast, RNA viruses (like HCV, HTLV-1) may encode oncogenes or trigger host oncogenes through cis-/-trans activation leading to different types of cancer. As for SARS-CoV-2, its role as an oncogenic virus seems to occur through the inhibition of oncosuppressors or controlling the metabolic and autophagy pathways in the infected cells. However, these effects could be significant in particular scenarios like those linked to severe COVID-19 or long COVID. On the other hand, looking at the SARS-CoV-2─cancer relationship from an opposite perspective, oncolytic effects and anti-tumor immune response were triggered by SARS-CoV-2 infection in some cases. In summary, our work aims to recall comprehensive attention from the scientific community to elucidate the effects of SARS-CoV-2 and, more in general, β-coronavirus infection on cancer susceptibility for cancer prevention or supporting therapeutic approaches.
好友两年前突然晕倒，查出肺癌初期，手术切除吃药似乎都正常了。最近又感觉不好，扩散了。又要手术化疗了。科技这么发达了，怎么癌症还不能攻克呢。
好像是的。好伤心。 难道真的跟疫苗有关系吗
医生术前检查时一再说是早期，只要微创手术，不需要任何术后治疗。术后第一次见手术医生，得知是二期时，估计状态不是很好，没有想起来要病理报告。
谢谢你的信息，记下了。刚见了另外一个负责后续治疗的医生，说根据病情，要做先化疗。
好，我也觉得让她重拾信心最重要。
没有明显症状，细想过去一段时间有点儿消瘦，轻咳，以为跟过敏有关。回国偶然体检发现的。
我们firm最近两个同事得Cancer, 前后相差一个月，其中一个才40岁，太让人震惊了，弄得我心里嘀咕，今年firm风水不好？有点害怕