这药吃完5天有人发生反阳问题。最近新闻关于 Recent case reports document that some patients who were treated with Paxlovid experienced rebound COVID-19 infections and symptoms 2 to 8 days after completing a 5-day course of Paxlovid. The Centers for Disease Control and Prevention (CDC) has recently issued a Health Alert Network Health Advisory to update the public on the potential for COVID-19 rebound after Paxlovid treatments. www.ncbi.nlm.nih.gov/pmc/articles/PMC9258292/ Covid-19 rebound also seems to be more common in people who take Paxlovid compared with those who don’t take the antiviral, although it can happen in either circumstance. www.cnn.com/2022/11/16/health/paxlovid-rebound-study/index.html clinicaltrials.gov/ct2/results?cond=paxlovid&term=paxlovid&cntry=US&state=&city=&dist= 这里是美国招募参加这个药物实验的信息，愿意尝试的可以点进去看哪些医院在招募，目前还在招 clinicaltrials.gov/ct2/results?cond=&term=paxlovid&cntry=US&state=&city=&dist= 在中国上海也有招募，家人在上海的可以看看clinicaltrials.gov/ct2/results?cond=&term=paxlovid&cntry=CN&state=&city=&dist=Skipping doses or starting and stopping an antiviral medicine can allow a virus to change/adapt so that the antiviral is no longer effective. This is antiviral resistance. https://my.clevelandclinic.org/health/drugs/21531-antivirals 病毒药和抗生素一样需要吃完一个疗程，不吃完一个疗程会造成耐药，药物无效请看链接是值得信任的网站。 Paxlovid, a common COVID-19 medication, can reduce the duration and lessens the likelihood of hospitalization from the coronavirus, but only if taken within five days of COVID symptoms beginning. “What we’re seeing is a lot of patients who test positive, then a week later are calling their physicians saying they still don’t feel well, and by then, it’s too late to start taking the antivirals,” said Erica Kaufman West, MD, a Franciscan Health infectious disease specialist. “We need to educate patients to understand that they have to start taking the antivirals within five days of symptom onset. If we can get patients informed so they can advocate for themselves or their family members, it will benefit all of us.” www.franciscanhealth.org/community/blog/pavloxid-early-covid-symptoms Because the drug is not approved by the U.S. Food and Drug Administration, but allowed under an emergency use authorization, doctors generally can’t prescribe it outside of the authorization criteria. Who Should Take Paxlovid? Why It''''''''s Not for Everyone | Timetime.com/6198667/paxlovid-who-should-take-covid-19/ Paxlovid is a highly effective treatment against COVID-19. In clinical trials, Paxlovid was shown to have an 88% reduction in hospitalization and death. Paxlovid must be started within 5 days of symptom onset. www.nmhealth.org/publication/view/general/7632/#:~:text=Paxlovid%20is%20a%20highly%20effective,reduction%20in%20hospitalization%20and%20death.&text=Paxlovid%20must%20be%20started%20within%205%20days%20of%20symptom%20onset. Paxlovid is given twice daily for 5 days, starting as soon as possible and within 5 days of symptom onset, and is approved for use in adult and pediatric patients (12 years of age and older weighing at least 40kg)./www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/outpatient-treatment-overview.html
美国现在每天死300-400
美国icu没有挤兑
能挺过前10天 基本就自愈了
不可能自愈, 上了医院唯一的一台呼吸机，才开始用的药
谢谢！目前在家里测已经转阴。大概是22号出现的阳的症状。
请问用的时候已经是重症了吗？
如果已经转阴，说明体内病毒清除得差不多了？这时候的症状是肌体本身免疫反应引起的，应该上激素控制炎症吧？
国内的明天上午家人带她去医院检查CT，看看医生怎么说。国内家人觉得现在医院交叉感染风险大，人多未必有床位，一直在家自己给吸氧、口服抗生素治疗。不想去医院，这也是让我很焦虑的事情。希望他们明天能带妈妈去医院检查。
MM可以给出这个指南的出处吗？我妈的医生是个中医，除了抗生素什么都不给开，想用这个请医生参考一下。非常感谢！
是重症，7天的时候住院，婆婆的医生是朋友，用了唯一的一台呼吸机，各种药，阿兹夫定，还是每况愈下，10天的时候医生让家人去找辉瑞，当天找到，用药第二天血氧就上到97
https://www.huxijie.com/documents/%E5%A4%B4%E6%9D%A1/5641/ 「中日医院成人Omicron病毒感染初始诊疗方案」发布，国家呼吸医学中心牵头！
吃過的朋友 陽康三個月到現在得看心肺專科
非常感谢！希望那个医生看到这个可以考虑！医生都是不喜欢家属乱提意见但是同行的话还是会听的
谢谢！请问用药的时候是阳性还是已经转阴了呢？
辉瑞这个药在中国好像特别好用，也许是因为没有人民的希望？希望哪个医生能总结一下病例，这个美国辉瑞自己都没有重症的数据。
不错 希望露珠妈妈尽快康复
真逗 网上的文章 怎么就成了同行的话了 赶紧换歌靠谱医生要紧
罗宾吃的阿兹夫定，你看他视频
也许就是有用。 辉瑞根本没在重症里面做study, 估计不想抢remdesivir 的market. 所以说，目前是没有证据能证明它在重症里有效，而不是说已知它对重症无效。至少看着中国case reports 是很多有效的。
因为药是免费的，高危人群基本上一得了就拿药吃了，不会等到重症。如果是重症了，基本上是吃了也不管用的。