新变种 BA.4 和 BA.5 带有Delta的 L452R 和 新的 F486V，更容易入侵人体。 Both new variants carry an L452R mutation, which was also previously detected in the Delta variant, and is thought to make the virus more contagious by enhancing the virus’s ability to attach to human cells; it may also help it to partially evade destruction by immune cells. They also possess a genetic change, called a F486V mutation, near where their spike protein binds to human cells. This may also help them partially evade our immune response. Unlike the BA.2 variant, most BA.4 and BA.5 sequences also contain a genetic change that affects the readout of certain routine PCR tests, leading to a phenomenon called S-gene dropout This provides a quick – although not conclusive – means of tracking these sub-variants in countries where BA.2 is dominant. https://www.gavi.org/vaccineswork/five-things-weve-learned-about-ba4-and-ba5-omicron-variants Omicron BA.1 和 BA.2 康复者仍然会被传染上。 https://www.medpagetoday.com/special-reports/exclusives/99281
新变种 BA.4 和 BA.5 带有Delta的 L452R 和 新的 F486V，更容易入侵人体。 Both new variants carry an L452R mutation, which was also previously detected in the Delta variant, and is thought to make the virus more contagious by enhancing the virus’s ability to attach to human cells; it may also help it to partially evade destruction by immune cells. They also possess a genetic change, called a F486V mutation, near where their spike protein binds to human cells. This may also help them partially evade our immune response. Unlike the BA.2 variant, most BA.4 and BA.5 sequences also contain a genetic change that affects the readout of certain routine PCR tests, leading to a phenomenon called S-gene dropout This provides a quick – although not conclusive – means of tracking these sub-variants in countries where BA.2 is dominant. https://www.gavi.org/vaccineswork/five-things-weve-learned-about-ba4-and-ba5-omicron-variants Omicron BA.1 和 BA.2 康复者仍然会被传染上。 https://www.medpagetoday.com/special-reports/exclusives/99281 meraviglia 发表于 2022-06-18 09:19
五月初得的大机率是BA.2.12.1, 是会再得BA.4／BA.5。 It only took about a month for BA.2.12.1, an Omicron subvariant, to cause most of the new COVID-19 cases in the U.S. since scientists first spotted it in the country. But even newer iterations of the Omicron variant are spreading rapidly through the U.S. and are poised to outcompete past versions of the virus, reinfect millions of Americans, and extend the country’s current COVID-19 surge. BA.4 and BA.5 now account for more than 21% of new cases in the U.S., according to U.S. Centers for Disease Control and Prevention (CDC) estimates as of June 11. These two new subvariants evolved from the Omicron lineage to become even more contagious and can bypass immunity from a past infection or vaccination, experts say. This means people can be reinfected even if they had Omicron earlier this year. https://time.com/6187762/ba-4-ba-5-omicron-subvariants-symptoms-risk/
omicron特异性疫苗对omicron也只有短期效果，长期来看会不会更糟还不一定呢。 而且ba1/2已经过气了。ba4/5的免疫逃逸现象相当明显。而且巧不巧，变化最大的地方就是mrna疫苗截取的那个spike protein 其实这也是理所当然。leaky vaccine必然带来额外选择压力，加速免疫逃逸。
Lack of Funding, Foresight and Good Fortune#ReinFections (we put the F in Reinfections) are nearing 1 out of every 5 detected cases almost everywhere with BA.4/ BA.5 and BA.5.1
Just published @Nature The extent of immune evasiveness of Omicron subvariants BA.2.12.1 and BA.4/5 raises concern about effectiveness of the Omicron (BA.1) specific vaccine booster impacthttps://t.co/foDTHDo49ppic.twitter.com/2WmXQHmRwr — Eric Topol (@EricTopol) June 17, 2022
Both new variants carry an L452R mutation, which was also previously detected in the Delta variant, and is thought to make the virus more contagious by enhancing the virus’s ability to attach to human cells; it may also help it to partially evade destruction by immune cells. They also possess a genetic change, called a F486V mutation, near where their spike protein binds to human cells. This may also help them partially evade our immune response.
Unlike the BA.2 variant, most BA.4 and BA.5 sequences also contain a genetic change that affects the readout of certain routine PCR tests, leading to a phenomenon called S-gene dropout This provides a quick – although not conclusive – means of tracking these sub-variants in countries where BA.2 is dominant.
https://www.gavi.org/vaccineswork/five-things-weve-learned-about-ba4-and-ba5-omicron-variants
Omicron BA.1 和 BA.2 康复者仍然会被传染上。
https://www.medpagetoday.com/special-reports/exclusives/99281
小朋友上学，没法不扎堆，这个最头疼。
南非屁事没有，你这每天打鸡血的招焦虑
我们是在听天由命。
我前几天看到的新闻说是4和5比1和2更容易感染肺部
系统提示：若遇到视频无法播放请点击下方链接
https://www.youtube.com/embed/5hr4v4s8tEo?showinfo=0
现在版本的疫苗防不了，Omicron版本的疫苗是针对BA.1，估计也不行。
怎么算认真抗议？上海那样吗？
五月初得的大机率是BA.2.12.1, 是会再得BA.4／BA.5。
It only took about a month for BA.2.12.1, an Omicron subvariant, to cause most of the new COVID-19 cases in the U.S. since scientists first spotted it in the country. But even newer iterations of the Omicron variant are spreading rapidly through the U.S. and are poised to outcompete past versions of the virus, reinfect millions of Americans, and extend the country’s current COVID-19 surge.
BA.4 and BA.5 now account for more than 21% of new cases in the U.S., according to U.S. Centers for Disease Control and Prevention (CDC) estimates as of June 11. These two new subvariants evolved from the Omicron lineage to become even more contagious and can bypass immunity from a past infection or vaccination, experts say. This means people can be reinfected even if they had Omicron earlier this year.
https://time.com/6187762/ba-4-ba-5-omicron-subvariants-symptoms-risk/
新闻 经过这两年还相信新闻的 嗯 不知说啥了 fool me once shame on you, fool me twice shame on me!
因为美国人脑子还没坏掉 知道这个根本不像新闻啊 宣传啊说的那么可怕
我转达一下新闻所述，信与不信可以慢慢观察疫情的发展，犯得上这么早就草率下结论然后给别人扣个帽子吗？
就是因为美国人脑子坏掉的太多才会被政客和主媒忽悠的打了不少针得了不少病。
政客和资本利益集团轻描淡写疫情是因为有利益所在，一个个小老百姓被忽悠的扎了不少针感染了一次又一次病毒，还在那里傻乐呵个啥呢？
猴痘的发生也很可疑。怎么就突然间散开来了
即便打了三针也比天天做核酸捅鼻子捅喉咙关在家里强百倍。
斗大的字 “恢复了delta的致病片段”假装看不见
ba5是走肺的，跟ba1ba2不可同日而语
就服你们的反智鸵鸟样儿。
最新的nature论文，不管感染omicron之前的covid版本还是打疫苗，都会损害对omicron的抵抗力。也就是免疫原罪实锤
然后omicron的免疫逃逸也实锤了。 omicron恢复一个月以后，对这个毒株的抵抗力与普通人没有任何区别。
所谓的群体免疫早就彻底破产。现在遮遮掩掩的，不敢报道而已。
链接？
https://huaren.us/showtopic.html?topicid=2817121&postid=93568637#93568637
omicron特异性疫苗对omicron也只有短期效果，长期来看会不会更糟还不一定呢。
而且ba1/2已经过气了。ba4/5的免疫逃逸现象相当明显。而且巧不巧，变化最大的地方就是mrna疫苗截取的那个spike protein
其实这也是理所当然。leaky vaccine必然带来额外选择压力，加速免疫逃逸。
然后每次的新变种都扣到印度，扣到非洲头上。
全世界病例最多，人种最多样，疫苗种类最多，人口流动最便捷的国家，没有诞生过一个新变种。
我信你个鬼
这么吓人啊，那怎么办？ 赶紧lockdown天天测核酸吧，要么再多打几针疫苗？
我觉得真正的致死率应该远小于目前公布的数据。过去一个月周围朋友同事得新冠的有30例了，几乎全是在家里自己测得，只有一个人出去药房测了PCR，然后得了就在家里修养几天就好了，所有在家测的人都没有上报任何机构。这样看起来得新冠的人数应该远远多于公布的数据。而且这些没上报的全是轻症或者无症状
有一说一，美国疫苗接种率远高于非洲和南非。美国不打疫苗的主要人群生活区域人口密度并不高。美国的公共卫生状况，以及艾滋病感染人群比例要远小于南非。
呵呵，等致死率上来你再来BB 有种你天天呆家里吧，没人在乎你怎么抗疫。
然后怎么办呢，封城？常态核酸税？付红码？
去医生那里看看 也许是普通病毒 也许是普通肺炎 就赶紧吃抗生素 他们听听肺就知道了