年龄大一些的孩子，身体耐受力强 mRNA疫苗能引起肝炎，去年就有文章证明了 Immune-mediated hepatitis with the Moderna vaccine, no longer a coincidence but confirmed - Journal of Hepatology (journal-of-hepatology.eu)
年龄大一些的孩子，身体耐受力强 mRNA疫苗能引起肝炎，去年就有文章证明了 Immune-mediated hepatitis with the Moderna vaccine, no longer a coincidence but confirmed - Journal of Hepatology (journal-of-hepatology.eu)
We have read with interest the recent cases suggesting the possibility of vaccine-induced immune-mediated hepatitis with Pfizer-BioNTech and Moderna mRNA-1273 vaccines for the SARS-CoV-2 virus.[1], [2], [3], [4], [5], [6], [7] However, as the cohort of vaccinated individuals against COVID-19 increases, the previously reported cases could not exclude a coincidental development of autoimmune hepatitis, which has an incidence of 3/100,000 population per year.8 Our case demonstrates conclusive evidence of vaccine-induced immune-mediated hepatitis with a rapid onset of liver injury after the first Moderna dose, which on re-exposure led to acute severe autoimmune hepatitis 拜托，先打搜索下原文看看再说。
There’s a mysterious outbreak of hepatitis in children. The WHO is investigating a possible connection to COVID An outbreak of severe hepatitis in children has continued to grow, with new cases now identified in the U.S., the World Health Organization (WHO) reported this weekend. The WHO published its first report on the outbreak on April 15, when cases were isolated in the United Kingdom. At the time of that report, there were a total of 10 cases in children between the ages of 11 months and 5 years old. No cause has been identified as of yet. As of last week at least 169 cases of acute hepatitis, or liver inflammation, of unknown origin had been reported in children between the ages of 1 month and 16 years old. While still concentrated in the U.K., additional cases have appeared in Spain, Israel, the U.S., Denmark, Ireland, the Netherlands, Italy, Norway, France, Romania, and Belgium. At least one death has been reported, according to the WHO. The common viruses associated with acute viral hepatitis—hepatitis A, B, C, D, and E—have not been identified in any case. Adenovirus, a class of common viruses that typically cause self-limiting infections in humans, has been identified in at least 74 cases, according to the report. The WHO is also investigating connections between the outbreak and COVID, which was identified in 20 cases. Beyond acute hepatitis and elevated levels of liver enzymes, symptoms in the reported cases have included abdominal pain, diarrhea, vomiting, and jaundice. Adenoviruses, which typically spread from person to person, most often cause respiratory symptoms like coughing, sore throat, and runny nose. Depending on the specific type, those affected can also develop gastroenteritis, pinkeye, and bladder infection, among other symptoms. There are more than 50 adenovirus types that can infect humans, according to the WHO’s report. Of the cases that had access to molecular testing, 18 were identified as involving adenovirus type 41, which has never before been closely linked with severe hepatitis. It most often causes diarrhea and vomiting. “While there have been case reports of hepatitis in immunocompromised children with adenovirus infection, adenovirus type 41 is not known to be a cause of hepatitis in otherwise healthy children,” said the WHO in its report. The high incidence of adenovirus infections associated with the hepatitis outbreak could simply be due to better testing, according to the WHO. “While adenovirus is currently one hypothesis as the underlying cause, it does not fully explain the severity of the clinical picture,” said the WHO. The WHO said that hypotheses relating to side effects of the vaccine are not supported, since most affected children had not been vaccinated. In the U.S. children under 5 are still not approved for the vaccine. The U.S. Centers for Disease Control and Prevention (CDC) has previously linked COVID with Multisystem Inflammatory Syndrome in Children (MIS-C), a condition characterized by inflammation of different organs. A paper published in the scientific journal Hepatology in late 2020 identified hepatitis as a common symptom in children afflicted with MIS–C. “Further work is required to identify additional cases, both in currently affected countries and elsewhere,” the WHO said in regard to proper public health response to the hepatitis outbreak. “Common prevention measures for adenovirus and other common infections involve regular hand washing and respiratory hygiene.” 另外，从其他的新闻网站上我还看到有统计患者年龄从1个月到16岁，其中17人需要肝移植，至少一人死亡。 病例至少169例，其中74例感染腺病毒，20例感染新冠，19例同时感染新冠病毒和腺病毒
年龄大一些的孩子，身体耐受力强 mRNA疫苗能引起肝炎，去年就有文章证明了 Immune-mediated hepatitis with the Moderna vaccine, no longer a coincidence but confirmed - Journal of Hepatology (journal-of-hepatology.eu)
We have read with interest the recent cases suggesting the possibility of vaccine-induced immune-mediated hepatitis with Pfizer-BioNTech and Moderna mRNA-1273 vaccines for the SARS-CoV-2 virus.[1], [2], [3], [4], [5], [6], [7] However, as the cohort of vaccinated individuals against COVID-19 increases, the previously reported cases could not exclude a coincidental development of autoimmune hepatitis, which has an incidence of 3/100,000 population per year.8 Our case demonstrates conclusive evidence of vaccine-induced immune-mediated hepatitis with a rapid onset of liver injury after the first Moderna dose, which on re-exposure led to acute severe autoimmune hepatitis 拜托，先打搜索下原文看看再说。 foreverf 发表于 2022-04-25 18:23
🔥 最新回帖
而且美国目前发现的最大cluster在红州，如果是lockdown口罩疫苗引起的也应该先发蓝州吧...
🛋️ 沙发板凳
肝炎带口罩有预防做用吗？
话说打得hepatitis B 的疫苗对这次未知病毒一点用也没有吗？
一般的肝炎跟呼吸系统是没关系的，要么消化要么血液传播，新的这个好像是腺病毒引起的免疫系统对肝的攻击。我感觉口罩用处不大
现在应该全面查过这些得病小孩儿之间有没有关联了吧
上daycare吗？哪个州
https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON376
这种回复是得不到高赞的。
各个新闻媒体都报道了。
话说口罩用处不大。那怎么防范？ 多洗手？！
难道是新的病毒？在新冠病毒上加了这个腺病毒，利用新冠易传播特性，还有攻击内脏器官能力？
病例都是2021年，疫苗接种以后出现的，而且都是在打mRNA疫苗的国家，比较可疑
还有那么多打了疫苗的孩子怎么目前都没听说呢
不是乙肝啊，现在考虑是腺病毒啥的
不还有6岁的吗，红州倒是有可能有人喂奶到6岁
The cases were reported in children aged one month to 16 years old
这个范围没法都跟母乳有关了
你这个想法很有新意。这不是儿童直接打疫苗的问题。现在就是看到底是那个年龄段了，这很好排除的。
这些小孩都还在吃母乳？年龄分布从1month 到16岁。16岁肯定不吃母乳吧
5岁以下没打疫苗那就是吃奶吃的。5岁以上那就是自己打疫苗打的。。。
问题是现在信息没有公开，这些人打没打过疫苗都不清楚。
年龄大一些的孩子，身体耐受力强
mRNA疫苗能引起肝炎，去年就有文章证明了
Immune-mediated hepatitis with the Moderna vaccine, no longer a coincidence but confirmed - Journal of Hepatology (journal-of-hepatology.eu)
新冠疫苗面世才一年，很多病童在妈妈打上新冠疫苗前就戒奶了吧。
肝炎都是血液和接触传染，戴口罩没用吧。
打过的乙肝疫苗也一点效果都没有吗？
这个太可怕，赶紧留下证据。这篇不会被撤了吧。
现在这种情况还是说说如何预防吧？ 比如是不是多洗手？ 还有啥是妈妈们可以注意和做的？ （至于疫苗，想打的都打了，不想打的到现在也没有打。我觉得就不要为此争论了吧？）
现在的报道是孩子们都没有打过疫苗，少部分确诊过新冠
现在的方向是看孩子们是不是无症状新冠患者，还有就是最近一两年腺病毒几乎绝迹了，这个突然冒出来的变异了的腺病毒比较强。
准备甩锅给疫苗的洗洗睡吧
有啥办法，为了让它和疫苗扯上关系，反疫苗党也是很卖力了，16岁算什么，30岁都敢喂奶。
病毒引起的，怎么会没有传染性？
不是现有肝炎病毒中的任何一种。没有传染性就很奇怪了，甲乙丙丁戊肝都有传染性。暂时不相信没有传染性
Severe Hepatitis in Pediatric COVID-19 Swati Antala 1, Tamir Diamond, Larry K Kociolek, Amit A Shah, Catherine A Chapin Affiliations expand PMID: 35149651 DOI: 10.1097/MPG.0000000000003404 Abstract Hepatic involvement in COVID-19 is typically characterized as mild hepatitis with preserved synthetic function in children. Severe hepatitis is a rare complication of COVID-19 infection that has not been extensively described in the pediatric population. We report a case series of 4 previously healthy children who presented with significant hepatitis as the primary manifestation of COVID-19 infection. Two of these patients met criteria for acute liver failure. None of the patients had respiratory symptoms. One patient was found to have complement dysfunction resulting in microangiopathic features and was treated successfully with eculizumab. This case is in line with adult post-mortem data showing that more severe cases of hepatic dysfunction secondary to COVID-19 infection may be associated with complement activation and microangiopathic features. Liver function should be evaluated in cases of severe COVID-19, and SARS-CoV-2 infection should be considered as a cause of acute severe hepatitis even in patients without significant respiratory or other systemic symptoms. Copyright © 2022 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology.
今年发的文章。
WHO 的话还有可信度吗？
都说了大部分孩子没有打过疫苗。不是你想要的真相就不叫真相是吧
没有传染，那些得病的人是怎么得的？新冠刚开始的时候，也传说只针对亚洲人，欧美人不会感染，结果都看到了
We have read with interest the recent cases suggesting the possibility of vaccine-induced immune-mediated hepatitis with Pfizer-BioNTech and Moderna mRNA-1273 vaccines for the SARS-CoV-2 virus.[1], [2], [3], [4], [5], [6], [7] However, as the cohort of vaccinated individuals against COVID-19 increases, the previously reported cases could not exclude a coincidental development of autoimmune hepatitis, which has an incidence of 3/100,000 population per year.8 Our case demonstrates conclusive evidence of vaccine-induced immune-mediated hepatitis with a rapid onset of liver injury after the first Moderna dose, which on re-exposure led to acute severe autoimmune hepatitis
拜托，先打搜索下原文看看再说。
得过这种急性肝炎的小孩能完全康复吗？
An outbreak of severe hepatitis in children has continued to grow, with new cases now identified in the U.S., the World Health Organization (WHO) reported this weekend. The WHO published its first report on the outbreak on April 15, when cases were isolated in the United Kingdom. At the time of that report, there were a total of 10 cases in children between the ages of 11 months and 5 years old. No cause has been identified as of yet. As of last week at least 169 cases of acute hepatitis, or liver inflammation, of unknown origin had been reported in children between the ages of 1 month and 16 years old. While still concentrated in the U.K., additional cases have appeared in Spain, Israel, the U.S., Denmark, Ireland, the Netherlands, Italy, Norway, France, Romania, and Belgium. At least one death has been reported, according to the WHO. The common viruses associated with acute viral hepatitis—hepatitis A, B, C, D, and E—have not been identified in any case. Adenovirus, a class of common viruses that typically cause self-limiting infections in humans, has been identified in at least 74 cases, according to the report. The WHO is also investigating connections between the outbreak and COVID, which was identified in 20 cases.
Beyond acute hepatitis and elevated levels of liver enzymes, symptoms in the reported cases have included abdominal pain, diarrhea, vomiting, and jaundice. Adenoviruses, which typically spread from person to person, most often cause respiratory symptoms like coughing, sore throat, and runny nose. Depending on the specific type, those affected can also develop gastroenteritis, pinkeye, and bladder infection, among other symptoms.
There are more than 50 adenovirus types that can infect humans, according to the WHO’s report. Of the cases that had access to molecular testing, 18 were identified as involving adenovirus type 41, which has never before been closely linked with severe hepatitis. It most often causes diarrhea and vomiting. “While there have been case reports of hepatitis in immunocompromised children with adenovirus infection, adenovirus type 41 is not known to be a cause of hepatitis in otherwise healthy children,” said the WHO in its report. The high incidence of adenovirus infections associated with the hepatitis outbreak could simply be due to better testing, according to the WHO. “While adenovirus is currently one hypothesis as the underlying cause, it does not fully explain the severity of the clinical picture,” said the WHO. The WHO said that hypotheses relating to side effects of the vaccine are not supported, since most affected children had not been vaccinated. In the U.S. children under 5 are still not approved for the vaccine.
The U.S. Centers for Disease Control and Prevention (CDC) has previously linked COVID with Multisystem Inflammatory Syndrome in Children (MIS-C), a condition characterized by inflammation of different organs. A paper published in the scientific journal Hepatology in late 2020 identified hepatitis as a common symptom in children afflicted with MIS–C. “Further work is required to identify additional cases, both in currently affected countries and elsewhere,” the WHO said in regard to proper public health response to the hepatitis outbreak. “Common prevention measures for adenovirus and other common infections involve regular hand washing and respiratory hygiene.”
另外，从其他的新闻网站上我还看到有统计患者年龄从1个月到16岁，其中17人需要肝移植，至少一人死亡。 病例至少169例，其中74例感染腺病毒，20例感染新冠，19例同时感染新冠病毒和腺病毒
有十几例需要换肝的。那就是永久性损伤了吧。
晕死了，竟然还有这等好处。。。
原文就是明确的说因果关系被证实了。这篇的作者说，之前的文章并没有完全排除并发症的可能性，但是他们这篇文章可以完全排除，因而是确认了因果关系。
我看到的是，英国得病的小孩都没有打过疫苗。
最后是疫苗还可以预防这种危险的肝炎？
最后一句。 文中这种情况和这些孩子的急性肝炎完全不是一回事。
要是还是实在不懂，交点学费，我给你讲讲
你这是胡搅蛮缠了。原文和最近这些case没有任何字面上的关联。我也只是把你贴出来的原文解释了一下。我只是告诉你，你完全把原文的意思理解反了。但我本人不为原文做任何背书，也不对现在的这些case持任何立场。
那就是有传染性了可以这么理解吧
我看有些报道说大多激素疗法就治好了，有可能是自免疫
最开始贴这文章那楼，不就是想把这些孩子的肝炎和疫苗扯上关系吗？ 这里本来在就在讨论这些孩子的肝炎， 我就是说这篇文章里的case，和这些孩子的肝炎没有一分钱的关系， 你自己理解能力差，还说别人胡搅蛮缠。
意思是暂时没发现肝炎病人传染人的。 发病的都是单独病例。
可能不少小孩没打疫苗，不过很多小孩是低龄的，不打疫苗，母亲打了疫苗，母乳里面的刺突蛋白也能引起这样的问题
献血也不要有刺突蛋白的血液吧
激素能治的病多了，SARS不是用激素了，川普还上了激素。
我看美国的案例报道就没有提疫苗事，最好公开一下信息，也利于辟谣。
打针又多感染又多的国家和地区，以后各种毛病不会少的。
你别硬扯疫苗了。 就算病毒引起的急性肝炎，也是引发了自身的免疫反应，你不会以为病毒直接吃细胞吧。 激素治疗是常见的减轻急性炎症反应的方法，只是针对症状，和病因没任何关系。
因为这些个case都是独立的，没有发现close contact 也发病，所以说目前没有发现传染性，hepatitis除了infectious agents可以造成，还有其他原因比如autoimmune hepatitis
造成红眼病的腺病毒（adenovirus）有十几个serotype，得过一次还是可以再得
你贴了一段原文，然后给了完全错误的解读。我指出这个就把你给激怒了。
现在的情况，公布的信息量太少，没法看出规律，只能期待能更多的信息。
我有什么怒的。 你太看重自己了。
而且我也没解读，我觉得版上大多数人都能自己看懂。
我也觉得目前就说是疫苗造成的还是太早了 腺病毒一直都有，50多种serotype，clinical presentation都很不一样，有造成呼吸道感染，有造成胃肠道感染，有的感染眼睛，有的感染心脏，这次这个serotype 41发现在不少case里，至于是不是罪魁祸首还需要时间
报道一致的说法，是没找到病毒
新冠也是病毒，可是不是所有孩子都有新冠感染历史
而最早出现的病例，在以色列是2021年2月，这个时间很容易想到和什么重合
据说北卡和另外一个州比较多， 如果先在两个州出现那就是传染。
可以理解，只要是打完疫苗，感觉到的不舒服，就是疫苗后遗症。 就算没大疫苗，也许是周围打过疫苗的人，引发了环境磁场变化，导致没打疫苗的人生病。 打不过就加入，我能编的更有趣。
想起最初的那个王广发是不是在武汉病毒溅到眼角膜感染的，他有红眼病症状吗？
出现时间这么巧合，又是自身免疫性肝炎，又找不到病毒，当然要怀疑
没打过疫苗，母乳也能传送刺突蛋白，就像给婴儿输有刺突蛋白的血液，谁知道啥后果
新闻显然遗忘了这点
怎么可能恰好得的都没打过疫苗， 报道只是说和大部分没打过疫苗所以和打疫苗无关。 169例中20例感染过新冠， 这也看不出和新冠有直接关系。 虽然说最大的是16岁， 但是大部分应该都是更小的小孩。