这位就是几天前出来说他所在的费城儿童医院没有看到孩子因为新冠入院增多的那位疫苗专家，也是FDA研究是否批准疫苗的panel 上邀请的专家，他是支持全民打2针疫苗的但是不支持全民booster。坐等他啥时候被批成反疫苗被批倒批臭，居然跟唯一代表科学的福奇先生唱反调。 “The question is, if you keep priming and boosting with a strain, which is basically to make an immune response against the ancestral strain, will that limit your ability then to make an immune response to a virus, which is very much different than the ancestral?” said Dr. Paul Offit, a vaccine expert at Children’s Hospital of Philadelphia. Offit is describing a phenomenon immunologists call “original antigenic sin” in which the body’s immune system relies on the memory of its first encounter with a virus, sometimes leading to a weaker immune response when it later encounters another version of the virus. Vaccines can activate this phenomenon, too, said Offit, also a member of the Food and Drug Administration’s vaccine advisory committee. An example is with the human papillomavirus, or HPV, following the release of an updated vaccine that targeted nine strains of the virus instead of just four in the initial shot, he said. “If you got HPV4 and then got HPV9, knowing that the four strains in [HPV]4were also in [HPV]9, you had a very good immune response to the fourstrains, but you didn’t have as good as an immune response to the otherfive strains,” he said. Theoretically, it could apply to Covid, too, Offit said. He said that some experts have argued it may be better for those not at high risk of severe disease to wait to get a booster until a variant-specific option is available. He, along with Philip Krause and Marion Gruber, two former FDA officials, wrote an op-ed published Monday in The Washington Post that argued that booster shots should be restricted to those at high risk for severe disease, such as the elderly and those who live or work in high-risk settings, like health care workers. They said the original two doses of the mRNA vaccines are still working for most healthy adults. https://www.nbcnews.com/health/health-news/omicron-variant-best-strategy-omicron-boost-original-vaccine-rcna7451
“The question is, if you keep priming and boosting with a strain, which is basically to make an immune response against the ancestral strain, will that limit your ability then to make an immune response to a virus, which is very much different than the ancestral?” said Dr. Paul Offit, a vaccine expert at Children’s Hospital of Philadelphia.
Offit is describing a phenomenon immunologists call “original antigenic sin” in which the body’s immune system relies on the memory of its first encounter with a virus, sometimes leading to a weaker immune response when it later encounters another version of the virus.
Vaccines can activate this phenomenon, too, said Offit, also a member of the Food and Drug Administration’s vaccine advisory committee. An example is with the human papillomavirus, or HPV, following the release of an updated vaccine that targeted nine strains of the virus instead of just four in the initial shot, he said.
“If you got HPV4 and then got HPV9, knowing that the four strains in [HPV]4were also in [HPV]9, you had a very good immune response to the fourstrains, but you didn’t have as good as an immune response to the otherfive strains,” he said.
Theoretically, it could apply to Covid, too, Offit said.
He said that some experts have argued it may be better for those not at high risk of severe disease to wait to get a booster until a variant-specific option is available.
He, along with Philip Krause and Marion Gruber, two former FDA officials, wrote an op-ed published Monday in The Washington Post that argued that booster shots should be restricted to those at high risk for severe disease, such as the elderly and those who live or work in high-risk settings, like health care workers. They said the original two doses of the mRNA vaccines are still working for most healthy adults.
https://www.nbcnews.com/health/health-news/omicron-variant-best-strategy-omicron-boost-original-vaccine-rcna7451
明白的到现在肯定早明白了，不信的还要继续每两个月打针的，还要帮小孩打booster大有人在，拉也拉不住的。
这种的千万别拉，吃力不讨好，到时候他们感染了病毒还要怪你没让他们打booster。
关键是媒体要报道，不报道这些专家说啥都没人能听到看到