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疫苗遇到delta可能会导致ADE,最新研究文章来了
查看北美华人网今日新帖
最新回复:2021年8月12日 20点46分 PT
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m
mybbs
接近 4 年
楼主 (北美华人网)
Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination ? - Journal of Infection
Highlights • Infection-enhancing antibodies have been detected in symptomatic Covid-19 • Antibody dependent enhancement (ADE) is a potential concern for vaccines • Enhancing antibodies recognize both the Wuhan strain and Delta variants • ADE of Delta variants is a potential risk for current vaccines • Vaccine formulations lacking ADE epitope are suggested
In conclusion, ADE may occur in people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors) and then exposed to a Delta variant.
c
chloemama
接近 4 年
2 楼
哈哈,隔壁还一直诅咒我这个不打疫苗的 😂😂 当然,打疫苗的危害是什么?这个得自己找
m
mybbs
接近 4 年
3 楼
这是法国人写的,在经典传染病学期刊上的最新文章
m
minijing
接近 4 年
4 楼
看abstract他们只是做了做in vitro study,测了测affinity,结论是疫苗有引起ADE的potential risk。可是现有的感染数据并没有显现ADE,并没打过疫苗的重症更多。只能说是实验室数据和临床数据不合,科研里常见。
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Highlights • Infection-enhancing antibodies have been detected in symptomatic Covid-19 • Antibody dependent enhancement (ADE) is a potential concern for vaccines • Enhancing antibodies recognize both the Wuhan strain and Delta variants • ADE of Delta variants is a potential risk for current vaccines • Vaccine formulations lacking ADE epitope are suggested
In conclusion, ADE may occur in people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors) and then exposed to a Delta variant.