德国科学家很可能找到了腺病毒载体疫苗形成血栓的机理,他们也在优化,JJ疫苗稍微好一点。 mRNA疫苗不进入细胞核,不存在这样的问题。 https://www.ft.com/content/f76eb802-ec05-4461-9956-b250115d0577 Rolf Marschalek, a professor at Goethe university in Frankfurt who has been leading studies into the rare condition since March, said his research showed the problem sat with the adenovirus vectors that both vaccines use to deliver the genetic instructions for the spike protein of the Sars-Cov-2 virus into the body. The delivery mechanism means the vaccines send the DNA gene sequences of the spike protein into the cell nucleus rather than the cytosol fluid found inside the cell where the virus normally produces proteins, Marschalek and other scientists said in a released on Wednesday. Once inside the cell nucleus, certain parts of the spike protein DNA are spliced, or split apart, creating mutant versions, which are unable to bind to the cell membrane where important immunisation takes place. The floating mutant proteins are instead secreted by cells into the body, triggering blood clots in roughly one in 100,000 people, according to Marschalek’s theory. In contrast, mRNA-based vaccines, such as the jabs developed by BioNTech/Pfizer and Moderna, deliver the spike’s genetic material to the cell fluid and it never enters the nucleus.
Over 20 million doses of the AZ vaccine have been given in the UK so far. According to the MHRA, the risk of a serious blood clot as a result of the jab is approximately one in 250,000 people vaccinated, or four in a million. It’s also worth noting that Covid-19 itself carries a significant risk of blood clots; according to a study in the journal Thorax, the prevalence of pulmonary embolism and deep vein thrombosis in people with the virus was 7.8% and 11.2%, respectively. What’s more, around 10,000 people usually develop blood clots in the EU in any given month, while an estimated 3,000 blood clot cases occur monthly in the UK. The general population’s risk of cerebral venous sinus thrombosis (CVST) – one of the blood clot types observed in Vaxzevria recipients – is around five in a million; slightly higher than the risk associated with the vaccine. 四月初止,UK注射2千万AZ,数据显示严重血栓大概是一百万万人里四个。 我也是打的AZ,当初打的时候心里也是有点不安的,就怕这个小概率落到自己头上。但孩子们都回去上课了,打了还是安心些,毕竟和染上COVID比, 风险 还是低多了。我们同事朋友里40+的我听说的全是打的AZ,没听到有问题的。但再小的概率,发生到自己头上就是100%,哎,其实没事谁愿意打疫苗啊。 RIP.
(13) BBC Radio Newcastle on Twitter: "We are so sorry and saddened to share with you that after a short illness our beautiful colleague Lisa Shaw has died. Everyone at the station is devastated and thinking about Lisa’s lovely family. She was a brilliant presenter, a wonderful friend and a loving wife and mum. https://t.co/tw3Lc2YzBW" / Twitter
Lisa Shaw death: BBC presenter had blood clots after AstraZeneca jab, family Lisa Shaw death: BBC presenter had blood clots after AstraZeneca jab, family says | BBC | The Guardian
Lisa Shaw: Vaccine role in BBC presenter''''''''''''''''s death to be probed Lisa Shaw: Vaccine role in BBC presenter''''''''''''''''s death to be probed - BBC News
阿 一直感觉是辉瑞副作用少些
Rolf Marschalek, a professor at Goethe university in Frankfurt who has been leading studies into the rare condition since March, said his research showed the problem sat with the adenovirus vectors that both vaccines use to deliver the genetic instructions for the spike protein of the Sars-Cov-2 virus into the body.
The delivery mechanism means the vaccines send the DNA gene sequences of the spike protein into the cell nucleus rather than the cytosol fluid found inside the cell where the virus normally produces proteins, Marschalek and other scientists said in a released on Wednesday.
Once inside the cell nucleus, certain parts of the spike protein DNA are spliced, or split apart, creating mutant versions, which are unable to bind to the cell membrane where important immunisation takes place. The floating mutant proteins are instead secreted by cells into the body, triggering blood clots in roughly one in 100,000 people, according to Marschalek’s theory.
In contrast, mRNA-based vaccines, such as the jabs developed by BioNTech/Pfizer and Moderna, deliver the spike’s genetic material to the cell fluid and it never enters the nucleus.
就是周围人这么说没什么科学依据哈。只是认识的人反应激烈的似乎也都是辉瑞
因为打moderna的人更少吧?美国之外还没听说谁打moderna了,辉瑞到处都有。
和年龄极为相关 年龄下降一点 风险翻数倍 六十岁以上就没听说
英国这里有亚裔血栓死亡的 这个是腺病毒疫苗的罪过 mRNA 无妨
做人还能更mean一点么?
成人世界,自己的选择自己负责
装什么爱心泛滥的圣母?!
mean的是你。你还能更装一点。 就是不像44。
华人大妈就别酸了,这种事情数据上只是一个data,落到个体上就是一个生与死的问题。国内大部分人不仅是可以打灭活的问题,而是根本不需要打疫苗。完全可以等欧美因为疫苗死了多少人之后从长计议。
denvor的2个警察感染,2周内都不幸死了
国内现在很多地方的人都在排队打疫苗
至于你说的一个data,你就是蹲家里也有房子塌的危险,出门也有车祸的风险,也是一个data,落到个体上就是生与死的问题
国内人民排队抢疫苗,原来是为了国家去库存啊
国外药厂更注重利润。
利润应该不如中药注射液高。毕竟国内药厂基本不需要大量投入研发也不用担心被告赔偿天价
是啊 要是不去试验蝙蝠病毒 何至于拉着全人类倒霉。 我本来还以为试验蝙蝠病毒是为了找解药的,结果他妈的是为了找毒药!真搞出来手足无措依然只能通过原始的方式抗疫
并不只是个案报道,而是有过一些零星数据,不过不是全面比较。
台湾有位资深医生几个月前好像就分析过人种差别的影响,台湾政府看来接受这种观点,所以继续AZ施种。不知有多少台湾人已经打了。
中医是经方,靠经验的,这些经方流传几千年了。你作为个体,吃米面拉撒也就几十年。所以打疫苗产生血栓的是你在负责理赔?
证据?
她的嘴
Wow Newcastle! 这个机场我去啊!
头痛就是血管堵了吧。这个好像医生也没啥好办法,有亲戚周期性剧烈头痛去看病,查不出来啥
美国人确实没有必要打J&J. 但是如果美国自己不批准,怎么能给世界其他国家用呢? 再说了,除了Pfizer/BioNTech, Moderna, 其他疫苗也不如J&J吧, J&J的血栓问题没有AZ严重,拿给第三世界国家也不错。
家有小娃的不用担心 现在根本不给小娃打新病毒疫苗 而且实验都被无限期暂停了
女性 年纪轻(aka更年期以前)的是重灾区
我们这里说是每六万针死一个 (不是六万个中发病一个)
J&J可能是因为吸取了经验就没给年轻人上 所以没有那么多例子 同时现在知道怎么救了 比原来用错药来一个死一个好一点 但是死亡率也极高 救回来也大概率对身体有毁灭性影响 所以很多国家都不用了
第三世界就是没办法只能硬着头皮打 其实第三世界年轻人比例更高 出问题概率更大
被韩国停了。
强生的疫苗在美国每六万针死一个吗?
胡扯。新冠疫苗是有政治任务的。
就像给志愿军的衣物里面加草而不是棉花,这样的资本家被抓到是要杀头的。
折损了党的权威。
AZ
JJ 数据相比于AZ太少了 而且,说实话,JJ这边数据透明度很差
不会啊 纽约的penn station 里打的就是强生啊 我看到很多年轻人在打
为什么透明度很差?样本太小了吗?
流传了几千年都搞不清楚副作用是什么。
JJ,moderna, 辉瑞现在都是随便预约打,并没有任何一个有明显更严重的副作用。包括大学给年轻学生打也有选择jj的,认识的人选择jj是因为只需要打一针。
今天去打的p 家第二针,打完5分钟,感觉从颈底部有一股小分队冲刺般向上冲,瞬间刺痛。是不是病毒在血管游走。。。。
咳咳,家有小娃的年轻女性尽量避免,要养娃的,风险防范要高一些。
韩国已经恢复三十岁以上的施打AZ疫苗了。
可能是小凝血块随着血管流动?病毒不会感觉出来吧
什么是小凝血块随着血管流动?
我看到说国内已经6亿人打了第一针了???难道是假新闻???
不是排队,是抢着打。广州爆了以后,我朋友说现在是一针难求,之前很多人都是观望的状态。感觉印度变种如果没有疫苗很难控制
就是,染上新冠,死亡可能比打疫苗打死的可能大太多了
是的
他/她为他们的选择负责,但你却有机会选择做个人
从长计议? 那现在着什么急下政治任务打什么没用的国产疫苗?
你吃了几十年饭,也有不清不楚的副作用,会让你变老然后死掉
谁不是人?是你吗?别人比你更是人。 一个句子到处用,烦不烦。
它的脑洞?
说白了还是领导没文化,不知道科研人员几斤几两。Sars之后这么多年都没研究出任何解药,第二年还泄露过一次,也不长记性,还研究蝙蝠。闹出新冠简直就是必然的结果。
你 TM 有病吧
人民日报官方论调,连洋五毛都是这个观点: http://world.people.com.cn/n1/2020/1127/c1002-31946850.html
还有负责外宣抹黑mRNA疫苗的喉舌-环球时报英文版 https://www.globaltimes.cn/page/202101/1212915.shtml
Meanwhile, toxic substances may be developed throughout the process of mRNA vaccinations; thus, the safety of vaccines cannot be fully ensured, Yang said. But that''s not the case for inactivated vaccines in China, which have more mature technology, Yang said.
我一直觉得其他动物都比很多人可爱多了,下辈子如果有机会,还真不屑做人
两者有什么关系吗?
四月初止,UK注射2千万AZ,数据显示严重血栓大概是一百万万人里四个。 我也是打的AZ,当初打的时候心里也是有点不安的,就怕这个小概率落到自己头上。但孩子们都回去上课了,打了还是安心些,毕竟和染上COVID比, 风险 还是低多了。我们同事朋友里40+的我听说的全是打的AZ,没听到有问题的。但再小的概率,发生到自己头上就是100%,哎,其实没事谁愿意打疫苗啊。
RIP.