转贴，可信性自行评估。 先贴链接：https://nationalfile.com/report-pfizer-vaccine-confirmed-to-cause-neurodegenerative-diseases/ A new report has determined the Pfizer vaccine can cause Alzheimer's and other conditions. In a shocking new report on the COVID-19 vaccines, it has been discovered that the Pfizer coronavirus vaccine has long term health effects not previously disclosed, including “ALS, Alzheimer’s, and other neurological degenerative diseases.” “The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing,” the report declares. “In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients.” Prion-based diseases are, according to the CDC, a form of neurodegenerative diseases, meaning that the Pfizer vaccine is likely to cause long term damage and negative health effects with regards to the brain. This is especially concerning since the Pfizer vaccine is an mRNA vaccine, an untested type of vaccine which creates new proteins and can actually integrate into the human genome, according to a report from the National Library of Medicine. In other words, degenerative brain conditions may appear at any time in your life after receiving the vaccine. “The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations,” explains the report. TDP-43 is a protein known to cause dementia, ALS and even Alzheimer’s, according to Alzpedia. Similarly, the FUS protein is known to cause ALS and Hereditary Essential Tremors, according to the Human Genome Database. The experiment done for the report was to determine whether or not these two harmful proteins embed themselves into our DNA, as an mRNA vaccine is expected to do. The report determined that “the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations,” meaning that both proteins have the potential to embed themselves into our DNA and cause harmful neurological diseases.
The report’s abstract summary concludes that “The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.” The report itself ends with this warning: “The vaccine could be a bioweapon and even more dangerous than the original infection.” National File actually reached out to the CDC to inquire as to why the Pfizer vaccine is still being distributed despite these credible allegations. No response was received prior to publication.
回复 1楼强制注册不注不行的帖子 看了一下报告。很短，连reference只有三页。其中最重要的就是以下这句话： The RNA sequence in the vaccine [3] contains sequences believed to induce TDP-43 and FUS to aggregate in their prion based conformation leading to the development of common neurodegerative diseases. 就是说疫苗中的一个RNA片段可以导致朊病毒。 我不懂医学，但是感觉这个还需要进一步研究。到底会产生多少，是否具有长期效应现在都不知道。我们身体里本来就有朊病毒，是否朊病毒都是有害的，致病机理是什么似乎现在也不是很明确。
回复 1楼强制注册不注不行的帖子 看了一下报告。很短，连reference只有三页。其中最重要的就是以下这句话： The RNA sequence in the vaccine [3] contains sequences believed to induce TDP-43 and FUS to aggregate in their prion based conformation leading to the development of common neurodegerative diseases. 就是说疫苗中的一个RNA片段可以导致朊病毒。 我不懂医学，但是感觉这个还需要进一步研究。到底会产生多少，是否具有长期效应现在都不知道。我们身体里本来就有朊病毒，是否朊病毒都是有害的，致病机理是什么似乎现在也不是很明确。
Haribough 发表于 2021-04-23 12:10
本来 spontaneous 的随机发生朊病毒病症的概率就是 1 over a million。原因不明。 不说概率没啥实际意义。量子力学一切都是概率。
“The experiment done for the report was to determine whether or not these two harmful proteins embed themselves into our DNA, as an mRNA vaccine is expected to do.” 这个观点都辟谣多少次了吧 mRNA是直接用来表达蛋白的 随后会在细胞内被降解掉 并不会把基因序列整合到人类的DNA里。
“The experiment done for the report was to determine whether or not these two harmful proteins embed themselves into our DNA, as an mRNA vaccine is expected to do.” 这个观点都辟谣多少次了吧 mRNA是直接用来表达蛋白的 随后会在细胞内被降解掉 并不会把基因序列整合到人类的DNA里。 Chipette 发表于 2021-04-23 13:28
关于作者，转自维基百科： John Barthelow Classen is an American immunologist and anti-vaccinationist. He received his M.D. from the University of Maryland, Baltimore in 1988, his M.B.A. from Columbia University in 1992 and obtained his medical license in October 1997.[1][2] He is best known for publishing research concluding that vaccines, in particular the Hib vaccine, cause insulin-dependent diabetes mellitus,[3] a hypothesis he proposed based on experiments he conducted on mice in 1996.[4] His views are disputed and considered unverified. A widely-reposted 2021 Facebook post claiming that the mRNA vaccines against COVID-19 could cause prion diseases was based on a paper by Classen. The paper was published in Microbiology and Infectious Diseases, whose publisher, Scivision Publishers, is included in Beall''''s list of publishers of predatory journals. Vincent Racaniello, professor of microbiology and immunology at Columbia University, described the claim as "completely wrong".[5][6][7]
网上碰到那些反对打疫苗说疫苗导致慢性病杀人的，问他们证据在哪里？数据在哪里？他们理直气壮的说it is all over the place, everywhere，还痛心疾首地说大家一定要做your own research, 千万不要被政府和比尔盖茨洗脑了，更不要觉得那些百万分之一概率发生的副作用肯定不会发生在你身上。听着好像很忧国忧民的，但是其实连最基本的科学是啥，医学是啥都不懂。他们所谓everywhere的证据就是这种文章。最可笑的是说不肯为一个1%死亡率的病去打杀人的疫苗（百万分之一的副作用率），还有人哭着喊着求家人不要打的，好像打了必死无疑的。
以下就是这篇文章所有的 “methods”部分 ， 没有任何删减。所有写过论文的人，都不会这么写文章吧。 Methods Pfizer’s RNA based vaccine against COVID-19 was evaluated for the potential to convert TDP-43 and or FUS to their prion based disease causing states. The vaccine RNA was analyzed for the presence of sequences that can activate TDP-43 and FUS. The interaction of the transcribed spike protein with its target was analyzed to determine if this action could also activate TDP-43 and FUS.
我让你找文献证明新冠疫苗在体内能检测到的时间，你给我一篇2018的文章干啥？我看你英文也不好吧? 拿着点过时的老知识当宝贝。人体内自身存在的逆转录酶文献早就有一堆了，只有你还以为只有病毒有，你没看哈佛MIT那篇文献吧，新冠病毒就是靠人体自身的逆转录酶插入基因组的，好人做到底，搬几句话给你看：we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from LINE-1 elements or by HIV-1 RT, and that these DNA sequences can be integrated into the cell genome and subsequently be transcribed. Human endogenous LINE-1 expression was induced upon SARS-CoV-2 infection or by cytokine exposure in cultured cells, suggesting a molecular mechanism for SARS-CoV-2 retro-integration in patients。Human LINE-1 accounts for ~17% of the human genome。 LINE-1 proteins have been shown as nucleic acid chaperones with high RNA binding affinity , therefore it is perhaps not surprising that they can retro-integrate exogenous viral RNAs 别整天说别人蠢了，这样只会暴露自己的智商和素质
A new report has determined the Pfizer vaccine can cause Alzheimer's and other conditions.
In a shocking new report on the COVID-19 vaccines, it has been discovered that the Pfizer coronavirus vaccine has long term health effects not previously disclosed, including “ALS, Alzheimer’s, and other neurological degenerative diseases.” “The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing,” the report declares. “In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients.” Prion-based diseases are, according to the CDC, a form of neurodegenerative diseases, meaning that the Pfizer vaccine is likely to cause long term damage and negative health effects with regards to the brain.
This is especially concerning since the Pfizer vaccine is an mRNA vaccine, an untested type of vaccine which creates new proteins and can actually integrate into the human genome, according to a report from the National Library of Medicine. In other words, degenerative brain conditions may appear at any time in your life after receiving the vaccine.
“The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations,” explains the report. TDP-43 is a protein known to cause dementia, ALS and even Alzheimer’s, according to Alzpedia. Similarly, the FUS protein is known to cause ALS and Hereditary Essential Tremors, according to the Human Genome Database. The experiment done for the report was to determine whether or not these two harmful proteins embed themselves into our DNA, as an mRNA vaccine is expected to do. The report determined that “the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations,” meaning that both proteins have the potential to embed themselves into our DNA and cause harmful neurological diseases.
The report’s abstract summary concludes that “The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.” The report itself ends with this warning: “The vaccine could be a bioweapon and even more dangerous than the original infection.” National File actually reached out to the CDC to inquire as to why the Pfizer vaccine is still being distributed despite these credible allegations. No response was received prior to publication.
取决于谁写的报告，哈哈。
给个链接我看看去
其实随便一个搞心血管的只要看了 小浣熊的那个帖子，都知道，北美6例血栓的治疗方案，是老年痴呆症最后阶段的治疗方法。也就是说，基因重组，提前触发和加快了老年痴呆症。
就是小浣熊的那个帖子，那里面的治疗方法就是老年痴呆症的治疗方案。 看样子，新肺炎的新型疫苗，都有可能提前触发老年痴呆症。
以前别人说你50c我还不信。
现在我觉得你大概价值5c。
对，不要相信名不见经传的右派小媒体，大家该打疫苗放心去打
如果实在不放心，还是打m家的
m家跟p家原理不是一样吗？
传染了COVID也有可能使老年痴呆症风险上升，brain fog不是报道的更多吗
这东西完全没有可信性。
我打算明天写个report，pfizer疫苗可以让丁丁增长五公分。
老川自己不都打疫苗了吗？支持者们还不跟进？
所以我说“实在不放心啊”
自己管好自己就行了，管别人干嘛？相信疫苗的就打，不相信疫苗就不打。很简单。
这个包括M家的？
而且 AZ 等这类 disease，原理一是基本还不清楚，还是个缓慢发展的过程，疫苗才不到半年，怎么能得出结论，要得结论也的起码两年后。。看看 打的老年人群是不是 AZ 发病率 有 jump ！ 如果原来是 40%， 现在一下子60%，才是 concern。。
还有，人啊现在之所以 癌症，老年痴呆发病率高，就是医疗/生活好了，寿命长了，原来4，50岁 一个感染就死了，都没机会的癌症，老年痴呆，这就是自然规律，现在还没啥办法！！
看了一下报告。很短，连reference只有三页。其中最重要的就是以下这句话：
The RNA sequence in the vaccine [3] contains sequences believed to induce TDP-43 and FUS to aggregate in their prion based conformation leading to the development of common neurodegerative diseases.
就是说疫苗中的一个RNA片段可以导致朊病毒。
我不懂医学，但是感觉这个还需要进一步研究。到底会产生多少，是否具有长期效应现在都不知道。我们身体里本来就有朊病毒，是否朊病毒都是有害的，致病机理是什么似乎现在也不是很明确。
本来 spontaneous 的随机发生朊病毒病症的概率就是 1 over a million。原因不明。
不说概率没啥实际意义。量子力学一切都是概率。
顺便说一下，mrna疫苗序列不会不同，谁家的疫苗都得含这个蛋白，最多以后加上变种的。这个帖子非常误导，华人本来就有信民科传统，版主考虑一下把这个帖子挪了吧。
两家用的序列是一样的
p就是摊子太大 先被盯上了呗
各大媒体早就被精英党收买了，任何关于疫苗副作用的帖子都删了，还会报道这个？
什么是“美国才三亿人，愿意怎么折腾就怎么折腾吧”？ 你国内翻墙来的？美国人的命就不是命是吧？
疫苗没问题，别耸人听闻了，只有不相信科学的保守右派才可能不去打，左派该打放心去打
这个report的问题还不是试管里的实验数据，而是连试管里的实验数据都没有，结论全靠编
有人拿IVIg试着治疗老年痴呆，同时IVig可以治疗很多免疫性疾病包括疫苗引起的血栓，但是你不能反过来说治疗过程中用了一样的药那得的病一定就是老年痴呆症
这个观点都辟谣多少次了吧 mRNA是直接用来表达蛋白的 随后会在细胞内被降解掉 并不会把基因序列整合到人类的DNA里。
我都觉得这篇文章是不是连基本biology都不懂的人写的
能不能给☝️小浣熊帖子的链接
五毛你别着急下定论啊 万一国内引进mRNA疫苗之后，钟南山老狗又出来做广告代言背书，到时候岂不是还得拼命180度转体高难度叼盘
五毛的骨头轻，180度大转弯算啥难度
懂行的能不能说说为啥这次美国不搞灭火疫苗啊？
没有P3实验室 --- 高福
"基因重组，提前触发和加快了老年痴呆症。"
You know what you are talking about? Do you know what genetic recombination is?
Mechanism of mRNA transport in the nucleus https://www.pnas.org/content/102/47/17008
MIT和哈佛合作发表:新冠的RNA可以逆转录和整合到人类基因组, 这说明新冠疫苗的RNA同样可以整合到DNA里 SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome https://www.biorxiv.org/content/10.1101/2020.12.12.422516v1.full.pdf
这篇文章讲病毒怎么进入细胞核 https://www.sciencedirect.com/science/article/pii/S0167488910003198
生物博士表示有点看不下去 第一篇难度不是讲mRNA怎么从细胞核到核外的过程吗？跟插入基因有什么关系？
后面两个，病毒能进核/逆转录，那是因为病毒带着相应的机制，疫苗又没有带这些。你这个逻辑相当于飞机能飞上天，所以飞机的起降轮拆下来以后也应该能飞上天
这个比喻太形象了
最牛就是怕一两个蛋白的mRNA，不怕整个病毒基因组的基因和蛋白，上哪儿说理去。
“这个逻辑相当于飞机能飞上天，所以飞机的起降轮拆下来以后也应该能飞上天”
必须赞比喻
真的绝了，自己发的链接自己不读的吗？是不是又是哪个群里看来，到处转发给别人看啊？
后两篇文章讲的是病毒RNA有嵌入人体DNA的机制。病毒RNA！不是疫苗里的mRNA！而且RNA分很多种，病毒的RNA并不是mRNA！mRNA本身是个极其不稳定的大分子！不是所有RNA都这样的。mRNA本身是不可以从细胞质进入细胞核的！
你不打疫苗，那么病毒进入你的身体，把RNA嵌入你的DNA，然后开始大量繁殖，你就是这么生病的，懂吗？
只有你打了疫苗，激活免疫系统，病毒还没来得及进入你的细胞呢，就被免疫系统消灭了，这就是疫苗的作用，OK？
没文化太可怕了。
John Barthelow Classen is an American immunologist and anti-vaccinationist. He received his M.D. from the University of Maryland, Baltimore in 1988, his M.B.A. from Columbia University in 1992 and obtained his medical license in October 1997.[1][2] He is best known for publishing research concluding that vaccines, in particular the Hib vaccine, cause insulin-dependent diabetes mellitus,[3] a hypothesis he proposed based on experiments he conducted on mice in 1996.[4] His views are disputed and considered unverified.
A widely-reposted 2021 Facebook post claiming that the mRNA vaccines against COVID-19 could cause prion diseases was based on a paper by Classen. The paper was published in Microbiology and Infectious Diseases, whose publisher, Scivision Publishers, is included in Beall''''s list of publishers of predatory journals. Vincent Racaniello, professor of microbiology and immunology at Columbia University, described the claim as "completely wrong".[5][6][7]
就知道有人会拿mRNA和RNA的区别来说，首先疫苗不是天然mRNA, 天然mRNA的确非常脆弱容易降解，所以人工合成的mRNA本身就加了不少东西来稳定它，没人知道这疫苗在体内会表达蛋白质多久，如果你有相关文献请列出。而且促进RNA逆转录插入DNA不需要病毒感染，细胞受到cytokine刺激就可能发生。打完疫苗各种炎症反应本身就会引发cytokine
RNA逆转录到DNA并不需要病毒感染,只要有cytokine就有可能, 第一篇和后面两篇逻辑紧密相连, 不知道你为什故意分开看.另外转3篇blog, 第一篇是采访这篇哈佛MIT合作的文章作者,第二和第三是作者自己写的blog. 作者自己都说了不能排除疫苗mRNA插入基因的可能性,你还这么确定不会? 我只是好心提醒大家有这个可能性, 打不打疫苗是个人决定
In my previous blog, “Will an RNA Vaccine Permanently Alter My DNA?”, I laid out several molecular pathways that would potentially enable the RNA in an mRNA vaccine to be copied and permanently integrated into our DNA. I was absolutely not surprised to find that the majority of people claimed that this prospect was impossible; in fact, I was expecting this response – partly because most people don’t possess a deep enough understanding of molecular biology, and partly because of other implicit biases.
https://pharmaceuticalfraud.com/2021-04-12-mrna-injections-permanently-alter-human-dna.html https://sciencewithdrdoug.com/2020/11/27/will-an-rna-vaccine-permanently-alter-my-dna/ https://sciencewithdrdoug.com/2021/02/15/breaking-study-sheds-more-light-on-whether-an-rna-vaccine-can-permanently-alter-dna/
Methods
Pfizer’s RNA based vaccine against COVID-19 was evaluated for the potential to convert TDP-43 and or FUS to their prion based disease causing states. The vaccine RNA was analyzed for the presence of sequences that can activate TDP-43 and FUS. The interaction of the transcribed spike protein with its target was analyzed to determine if this action could also activate TDP-43 and FUS.
哈哈哈！我先笑三声！
你知道为什么mRNA疫苗技术几十年没有进展，直到最近才研制出可用的疫苗吗？因为mRNA不稳定啊！mRNA一进入人体就被分解，所以要让mRNA起作用，必须包裹脂质外衣，帮助mRNA进入细胞质，一旦进入细胞质，外衣分解，mRNA开始表达蛋白，无论有没有脂质外衣，mRNA都进不了细胞核啊。您最后一句什么RNA逆转录，大哥，那不是mRNA，而且逆转录是需要逆转录酶的，而逆转录酶只有病毒才能表达啊大哥。要是人体自带逆转录酶，那人就不是人了，吃个蔬菜水果生鱼，随便感染个细菌真菌的，分分钟给你逆转录到人体DNA？开什么宇宙玩笑。而且就算有逆转录酶，逆转录酶也没法逆转录mRNA啊……
而且，研究已经很清楚了，疫苗mRNA打进人体引起免疫反应，几天后mRNA就被人体完全降解、检测不到了。来，文献甩给你，问题是你看得懂吗？https://www.nature.com/articles/nrd.2017.243#ref-CR9
真的，别讲了，越讲显得越蠢。
赞👍各位生物达人的讲解深入浅出，连我这个生物小白都看懂了。华人上果然卧虎藏龙！
谢谢科普
我让你找文献证明新冠疫苗在体内能检测到的时间，你给我一篇2018的文章干啥？我看你英文也不好吧? 拿着点过时的老知识当宝贝。人体内自身存在的逆转录酶文献早就有一堆了，只有你还以为只有病毒有，你没看哈佛MIT那篇文献吧，新冠病毒就是靠人体自身的逆转录酶插入基因组的，好人做到底，搬几句话给你看：we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from LINE-1 elements or by HIV-1 RT, and that these DNA sequences can be integrated into the cell genome and subsequently be transcribed. Human endogenous LINE-1 expression was induced upon SARS-CoV-2 infection or by cytokine exposure in cultured cells, suggesting a molecular mechanism for SARS-CoV-2 retro-integration in patients。Human LINE-1 accounts for ~17% of the human genome。 LINE-1 proteins have been shown as nucleic acid chaperones with high RNA binding affinity , therefore it is perhaps not surprising that they can retro-integrate exogenous viral RNAs 别整天说别人蠢了，这样只会暴露自己的智商和素质