自己看原文，原文明确说了该病人从去年6月4日到11月13日抗体测了6次， 体内抗体没有迹象表明减弱 a total of 22 routine NTS swabs were sent between the 5th May 2020 and the 1st of December 2020 and all tested negative for SARS-CoV-2 RNA. SARS-CoV-2 antibodies (using the Roche anti-SARS-CoV-2 IgM/IgG assay detecting antibodies targeting viral nucleocapsid ‘N’ antigen) were detectable on 6 occasions between the 4th June 2020 and 13th November 2020 with no evidence of antibody waning seen.
自己看原文，原文明确说了该病人从去年6月4日到11月13日抗体测了6次， 体内抗体没有迹象表明减弱 a total of 22 routine NTS swabs were sent between the 5th May 2020 and the 1st of December 2020 and all tested negative for SARS-CoV-2 RNA. SARS-CoV-2 antibodies (using the Roche anti-SARS-CoV-2 IgM/IgG assay detecting antibodies targeting viral nucleocapsid ‘N’ antigen) were detectable on 6 occasions between the 4th June 2020 and 13th November 2020 with no evidence of antibody waning seen. andyconnor 发表于 2021-01-10 03:25
自己看原文，原文明确说了该病人从去年6月4日到11月13日抗体测了6次， 体内抗体没有迹象表明减弱 a total of 22 routine NTS swabs were sent between the 5th May 2020 and the 1st of December 2020 and all tested negative for SARS-CoV-2 RNA. SARS-CoV-2 antibodies (using the Roche anti-SARS-CoV-2 IgM/IgG assay detecting antibodies targeting viral nucleocapsid ‘N’ antigen) were detectable on 6 occasions between the 4th June 2020 and 13th November 2020 with no evidence of antibody waning seen. andyconnor 发表于 2021-01-10 03:25
preprints.org > life sciences > biochemistry > doi: 10.20944/preprints202101.0132.v1 Preprint Case ReportVersion 1Preserved in Portico This version is not peer-reviewed Genomic Evidence of a Sars-Cov-2 Reinfection Case With E484K Spike Mutation in Brazil Version 1 : Received: 5 January 2021 / Approved: 6 January 2021 / Online: 6 January 2021 (20:38:36 CET) Abstract To date, uncertainty remains about how long the protective immune responses against SARS-CoV-2 persists and the first reports of suspected reinfection began to be described in recovered patients months after the first episode. Viral evolution may favor reinfections, and the recently described spike mutations, particularly in the receptor binding domain (RBD) in SARS-CoV-2 lineages circulating in the UK, South Africa, and most recently in Brazil, have raised concern on their potential impact in infectivity and immune escape. We report the first case of reinfection from genetically distinct SARS-CoV-2 lineage presenting the E484K spike mutation in Brazil, a variant associated with escape from neutralizing antibodies.
病人是一个78岁的糖尿病患者，四月得的时候是轻症，简单治疗后就出院了，确认新冠检测变阴，且体内测出抗体。而且regular测试抗体，最后一次测抗体是11月13日，抗体依旧存在，并且没有减轻。但是12月，此人被测出感染上了B117变种，并且直接变成critical illness重症。
https://www.reddit.com/r/Coronavirus/comments/ku6zzw/confirmed_reinfection_with_sarscov2_variant/ reddit讨论贴，上面有人说疫苗产生的抗体和自己感染痊愈的抗体不一样。疫苗产生的抗体，可能对变种有效，但是自己痊愈的抗体，从这个例子看出，不一定对变种有效了。
自己看原文，原文明确说了该病人从去年6月4日到11月13日抗体测了6次， 体内抗体没有迹象表明减弱 a total of 22 routine NTS swabs were sent between the 5th May 2020 and the 1st of December 2020 and all tested negative for SARS-CoV-2 RNA. SARS-CoV-2 antibodies (using the Roche anti-SARS-CoV-2 IgM/IgG assay detecting antibodies targeting viral nucleocapsid ‘N’ antigen) were detectable on 6 occasions between the 4th June 2020 and 13th November 2020 with no evidence of antibody waning seen.
这位的抗体半年都没减弱？估计是神人！前几天武汉金银潭的追踪数据都是半年内抗体水平都下降到一半以下。
「人们最关心的问题，也就是得过新冠后是否就无需担心再感染病毒，也有了答案。研究中有94人接受了血液抗体测试，相比于感染高峰时期，他们的中和抗体水平下降了52.5%，也就是说，他们仍有一定的再次被感染风险。」
你找这些人理论去，我只负责搬运，don''t shoot the messenger David Harrington, Beatrix Kele, Spiro Pereira, Xose Couto-Parada, Anna Riddell, Suzanne Forbes, Hamish Dobbie, Teresa Cutino-Moguel Barts Health NHS Trust London, UNITED KINGDOM
Corresponding author: David Harrington Barts Health NHS Trust London, UNITED KINGDOM Email: [email protected] 你可以email这个人，询问具体情况
这个测的是n antigen, 疫苗的是 s protein, n蛋白抗体没变不等于s蛋白的也没变
谢谢信息，那就更加证明了疫苗普及的必要性，不要因为得过新冠了就不打疫苗，在变种的威胁下，人人都应该尽快接种疫苗
所以灭活疫苗要歇菜？
多谢分享。关注，希望有内行帮着分析一下。需要劝家里老人打疫苗吗？
我觉得，这个病例，糖尿病是个关键，因为 变种感染率高，同样条件下，更容易被 变种感染，所以病人的身体条件，一旦再次被 感染，变重症的可能性概率比较大！ 这个如果是一个基本健康的个体，concern 可能会更高。
也是二次远比第一次严重
Version 1 : Received: 5 January 2021 / Approved: 6 January 2021 / Online: 6 January 2021 (20:38:36 CET)
Abstract To date, uncertainty remains about how long the protective immune responses against SARS-CoV-2 persists and the first reports of suspected reinfection began to be described in recovered patients months after the first episode. Viral evolution may favor reinfections, and the recently described spike mutations, particularly in the receptor binding domain (RBD) in SARS-CoV-2 lineages circulating in the UK, South Africa, and most recently in Brazil, have raised concern on their potential impact in infectivity and immune escape. We report the first case of reinfection from genetically distinct SARS-CoV-2 lineage presenting the E484K spike mutation in Brazil, a variant associated with escape from neutralizing antibodies.
又开始阿Q洗地了。谁能保证自己健康没有隐形疾病？