https://news.trust.org/item/20210108022715-m5obt Pfizer/BioNTech vaccine appears effective against mutation in new coronavirus variants -study NEW YORK, Jan 7 (Reuters) - Pfizer Inc and BioNTech''s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the UK and South Africa, according to a laboratory study conducted by the U.S. drugmaker. The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein.
https://news.trust.org/item/20210108022715-m5obt Pfizer/BioNTech vaccine appears effective against mutation in new coronavirus variants -study NEW YORK, Jan 7 (Reuters) - Pfizer Inc and BioNTech''s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the UK and South Africa, according to a laboratory study conducted by the U.S. drugmaker. The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein. 梅干茶泡饭 发表于 2021-01-07 23:05
你没有贴完.测了的部分有效.但是还有一些变种没有测. The researchers plan to run similar tests to see if the vaccine is effective against other mutations found in the UK and South African variants and hope to have more data within weeks.
https://news.trust.org/item/20210108022715-m5obt Pfizer/BioNTech vaccine appears effective against mutation in new coronavirus variants -study NEW YORK, Jan 7 (Reuters) - Pfizer Inc and BioNTech''''''''''''''''s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the UK and South Africa, according to a laboratory study conducted by the U.S. drugmaker. The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein. 梅干茶泡饭 发表于 2021-01-07 23:05
https://www.preprints.org/manuscript/202101.0132/v1 We report the first case of reinfection from genetically distinct SARS-CoV-2 lineage presenting the E484K spike mutation in Brazil, a variant associated with escape from neutralizing antibodies.
lz没贴全 The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein. The mutation could be responsible for greater transmissibility and there had been concern it could also make the virus escape antibody neutralization elicited by the vaccine, said Phil Dormitzer, one of Pfizer's top viral vaccine scientists. The study was conducted on blood taken from people who had been given the vaccine. Its findings are limited, because it does not look at the full set of mutations found in either of the new variants of the rapidly spreading virus. Dormitzer said it was encouraging that the vaccine appears effective against the mutation, as well as 15 other mutations the company has previously tested against. "So we've now tested 16 different mutations, and none of them have really had any significant impact. That's the good news," he said. "That doesn't mean that the 17th won't." Dormitzer noted another mutation found in the South African variant, called the E484K mutation, is also concerning.
NEW YORK, Jan 7 (Reuters) - Pfizer Inc and BioNTech''s COVID-19 vaccine appeared to work against a key mutation in the highly transmissible new variants of the coronavirus discovered in the UK and South Africa, according to a laboratory study conducted by the U.S. drugmaker. The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein.
这要问Moderna啊
你没有贴完.测了的部分有效.但是还有一些变种没有测.
The researchers plan to run similar tests to see if the vaccine is effective against other mutations found in the UK and South African variants and hope to have more data within weeks.
GOOD !!!
MOSTLY THEY ARE VERY SIMILAR, mRNA BASED, SO LIKELY EFFECTIVE TOO
谢谢!
道理是没错,就是怕病毒进化出利用其他受体的RBD. 记得还有另外一个受体可以用的,但是表达那个受体的细胞没有表达Ace2的多
lz是说uk变异和南非变异共有的那个吗?这个好像是预知会work的
hemonc同学讲的对,南非变异里有但uk变异里没有的那个才是有问题的
这里有一个在巴西的二次感染,第二次的strain测序就含有E484K Spike Mutation
https://www.preprints.org/manuscript/202101.0132/v1
We report the first case of reinfection from genetically distinct SARS-CoV-2 lineage presenting the E484K spike mutation in Brazil, a variant associated with escape from neutralizing antibodies.
+1
查了一下 大多数同一时间刊登了这篇新闻稿的媒体都还挺正直的 很清晰的说了仅包含british variant
The not-yet peer reviewed study by Pfizer and scientists from the University of Texas Medical Branch indicated the vaccine was effective in neutralizing virus with the so-called N501Y mutation of the spike protein.
The mutation could be responsible for greater transmissibility and there had been concern it could also make the virus escape antibody neutralization elicited by the vaccine, said Phil Dormitzer, one of Pfizer's top viral vaccine scientists.
The study was conducted on blood taken from people who had been given the vaccine. Its findings are limited, because it does not look at the full set of mutations found in either of the new variants of the rapidly spreading virus. Dormitzer said it was encouraging that the vaccine appears effective against the mutation, as well as 15 other mutations the company has previously tested against.
"So we've now tested 16 different mutations, and none of them have really had any significant impact. That's the good news," he said. "That doesn't mean that the 17th won't."
Dormitzer noted another mutation found in the South African variant, called the E484K mutation, is also concerning.
你要想变异是怎么来的 又是怎么会有选择优势的
昨天看推特上说疫苗不改变fatality rate 我还没去查过
我们都不担心。就是WM带节奏啊。
新的疫苗发展测试审批和发放都需要时间,人力和物力...有些传染疾病到现在也没有疫苗...