“Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets.” In extremely rare cases, the measles, mumps and rubella vaccine has been linked to thrombocytopenia in young children, according to a 2003 study. The condition can also be caused by cancer, anemia, heavy drinking, viruses, some genetic conditions, toxic chemicals and medications such as diuretics and the rarely used antibiotic chloramphenicol. Pfizer, which along with its partner BioNTech made the vaccine the man received, said in a statement it is aware of the death. "We are actively investigating this case, but we don''t believe at this time that there is any direct connection to the vaccine," the statement said.“ 虽然不能完全排除和疫苗的关系，但看来可能性很小。 作为药学的，我好奇他在服用什么药，因为大部分56岁的人起码在用一两个药。 同时导致血小板低的药品远远不止chloramphenicol （并且此药已经基本上没有人用了，只有本来会死定的级少数细菌感染才会用）。 更普遍的是heparin 或者LMWH (有名的), Zyvox (抗生素）, ranitidine或者famotidine （降胃酸的药），阿司匹林， sulfa drugs, 等等。 我的知识范围不适于评论其他导致血小板的原因。
“Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets.” In extremely rare cases, the measles, mumps and rubella vaccine has been linked to thrombocytopenia in young children, according to a 2003 study. The condition can also be caused by cancer, anemia, heavy drinking, viruses, some genetic conditions, toxic chemicals and medications such as diuretics and the rarely used antibiotic chloramphenicol. Pfizer, which along with its partner BioNTech made the vaccine the man received, said in a statement it is aware of the death. "We are actively investigating this case, but we don''t believe at this time that there is any direct connection to the vaccine," the statement said.“ 虽然不能完全排除和疫苗的关系，但看来可能性很小。 作为药学的，我好奇他在服用什么药，因为大部分56岁的人起码在用一两个药。 同时导致血小板低的药品远远不止chloramphenicol （并且此药已经基本上没有人用了，只有本来会死定的级少数细菌感染才会用）。 更普遍的是heparin 或者LMWH (有名的), Zyvox (抗生素）, ranitidine或者famotidine （降胃酸的药），阿司匹林， sulfa drugs, 等等。 我的知识范围不适于评论其他导致血小板的原因。 drugdealer 发表于 2021-01-07 19:55
对吃药与否不知，在结果没公布前我就不去揣测他吃或者没吃过什么药了。遗孀在fb的吊文里说自己的先生是“非常健康，56岁” 打疫苗后3天开始发现皮肤上有出血点就诊，发现血小板骤降，抢救几周，最后仍然去世。正式调查还在进行中，等结果吧。转这个新闻，希望大家心里有数就好。不盲信也不盲不信。 遗孀在Fb上写的“ "He was a very healthy 56-year-old, loved by everyone in the community, delivered hundreds of healthy babies and worked tireless through the pandemic," she said in the post, which had received more than 1,400 comments as of 8 p.m. Wednesday.”
“Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets.” In extremely rare cases, the measles, mumps and rubella vaccine has been linked to thrombocytopenia in young children, according to a 2003 study. The condition can also be caused by cancer, anemia, heavy drinking, viruses, some genetic conditions, toxic chemicals and medications such as diuretics and the rarely used antibiotic chloramphenicol. Pfizer, which along with its partner BioNTech made the vaccine the man received, said in a statement it is aware of the death. "We are actively investigating this case, but we don''t believe at this time that there is any direct connection to the vaccine," the statement said.“ 虽然不能完全排除和疫苗的关系，但看来可能性很小。 作为药学的，我好奇他在服用什么药，因为大部分56岁的人起码在用一两个药。 同时导致血小板低的药品远远不止chloramphenicol （并且此药已经基本上没有人用了，只有本来会死定的级少数细菌感染才会用）。 更普遍的是heparin 或者LMWH (有名的), Zyvox (抗生素）, ranitidine或者famotidine （降胃酸的药），阿司匹林， sulfa drugs, 等等。 我的知识范围不适于评论其他导致血小板的原因。 drugdealer 发表于 2021-01-07 19:55
“Dr. Gregory Michael, 56, an OB-GYN at Mount Sinai Medical Center in Miami Beach, died after suffering a hemorrhagic stroke apparently resulting from a lack of platelets.”
In extremely rare cases, the measles, mumps and rubella vaccine has been linked to thrombocytopenia in young children, according to a 2003 study. The condition can also be caused by cancer, anemia, heavy drinking, viruses, some genetic conditions, toxic chemicals and medications such as diuretics and the rarely used antibiotic chloramphenicol.
Pfizer, which along with its partner BioNTech made the vaccine the man received, said in a statement it is aware of the death. "We are actively investigating this case, but we don''t believe at this time that there is any direct connection to the vaccine," the statement said.“
虽然不能完全排除和疫苗的关系，但看来可能性很小。
作为药学的，我好奇他在服用什么药，因为大部分56岁的人起码在用一两个药。
同时导致血小板低的药品远远不止chloramphenicol （并且此药已经基本上没有人用了，只有本来会死定的级少数细菌感染才会用）。 更普遍的是heparin 或者LMWH (有名的), Zyvox (抗生素）, ranitidine或者famotidine （降胃酸的药），阿司匹林， sulfa drugs, 等等。 我的知识范围不适于评论其他导致血小板的原因。
对吃药与否不知，在结果没公布前我就不去揣测他吃或者没吃过什么药了。遗孀在fb的吊文里说自己的先生是“非常健康，56岁” 打疫苗后3天开始发现皮肤上有出血点就诊，发现血小板骤降，抢救几周，最后仍然去世。正式调查还在进行中，等结果吧。转这个新闻，希望大家心里有数就好。不盲信也不盲不信。 遗孀在Fb上写的“ "He was a very healthy 56-year-old, loved by everyone in the community, delivered hundreds of healthy babies and worked tireless through the pandemic," she said in the post, which had received more than 1,400 comments as of 8 p.m. Wednesday.”
你干嘛臆测人家用了血小板降低得药？就算他用药，想来也不是最近几天才开始用得，为什么打了疫苗几天后才发现出血？
搞不好真的要用巴西做过三期的疫苗。 牛津的在巴西就还没成功。
美国让我觉得有希望的一点是在全国全世界如此急需疫苗的情况下选择直面事实，而没有掩盖和否定，在媒体上消声这个事件。
作为药学研究多年的，我要指出什么是statistical signiant和什么不是的。
比如我说到的很多抗生素，zyvox和sulfaonamide是很普遍用的，但同时也通常不是长期用的药物。比如你得了尿道感染就用几天，皮肤炎用几天，各种感染等等绝大部分都是5到14天左右。
因此我们这些科学专业的经常做journal club, 评论各个科学论文。 其中很大一部分就是internal validity, external validity, generalizability, limitations等等。 这就是科学的基础和规则。 可惜得是经常大众虽然懂无知却会认为自己比科技人员还灵通。
这个也不完全可以这么说
有的毛病本身也是罕见病，但生了就是生了，不是statistical blip
药物产生的副作用也是的，不能说数量不大就没意义
不否认这个，但同时不支持这个。
科学不由各人猜测和想象，而是以实验和数据说明。我希望这个大家都能理解。 作为科学人员应该认识到打了5百万疫苗后有一个有可能或者不和疫苗有关得病例其实不显示statstical significance。
在医疗事业中，任何和疫苗有可疑反应得病例是通过VAERS系统报道和统计的。 FDA会不停的在发表任何对药物有可疑的反应。 作为药理和药疗的，我请大家关注这个，而不要在专业人员还没认为前去乱猜。
https://www.fda.gov/drugs/drug-safety-and-availability/drug-safety-communications
所以第二次疫苗接种的时候应该核酸检测一下，如果已经感染病毒，就不用注射第二针了，省下来给其他人注射
这也是一个可能
例子也要一个一个攒起来不是嘛