The vaccine developed by the University of Oxford stops 70% of people developing Covid symptoms, a large scale trial shows. It is both a triumph and a disappointment after vaccines by Pfizer and Moderna showed 95% protection. However, the Oxford jab is far cheaper, and is easier to store and get to every corner of the world than the other two. So it will still play a significant role in tackling the pandemic, if it is approved by regulators. The Oxford researchers have performed the normally decade-long process of developing a vaccine in around 10 months. The UK government has pre-ordered 100 million doses of the Oxford vaccine, enough to immunise 50 million people. What did the trial show? More than 20,000 volunteers were involved, half in the UK, the rest in Brazil. There were 30 cases of Covid in people who had two doses of the vaccine and 101 cases in people who received a dummy injection. The researchers said it works out at 70% protection. Intriguingly, the effectiveness rose to 90% in a group of volunteers who were given an initial half dose, followed by a full dose. It's not clear why there is a difference.
When will I get it? In the UK there are four million doses ready to go, with another 96 million to be delivered. But nothing can happen until the vaccine has been approved by regulators who will assess the vaccine's safety, effectiveness, and that it is manufactured to high standard. This will happen in the coming weeks. However, the UK is ready to press the go button on an unprecedented mass immunisation campaign that dwarfs either the annual flu or childhood vaccination programmes. Care home residents and staff will be first, followed by healthcare workers and the over 85s. The plan is to then work the way down the age groups.
回复 2楼andyconnor的帖子 Intriguingly, the effectiveness rose to 90% in a group of volunteers who were given an initial half dose, followed by a full dose. It's not clear why there is a difference. 这个有意思
回复 2楼andyconnor的帖子 Intriguingly, the effectiveness rose to 90% in a group of volunteers who were given an initial half dose, followed by a full dose. It's not clear why there is a difference. 这个有意思 ytwk1 发表于 2020-11-23 02:40
认真读一下就知道了： The trial looked at two different dosing regimens. A half dose of the vaccine followed by a full dose at least one month apart was 90 per cent effective. A second regimen using two full doses one month apart was 62 per cent effective. The combined results showed an average efficacy rate of 70 per cent. https://www.cbc.ca/news/world/vaccine-covid-19-astrazeneca-1.5812268
flu shot没有这么高 1/3到1/2 According to a Feb. 21 CDC Morbidity and Mortality Weekly Report, the current influenza vaccine has been 45% effective overall against 2019-2020 seasonal influenza A and B viruses. Specifically, the flu vaccine has been 50% effective against influenza B/Victoria viruses and 37% effective against influenza A(H1N1)pdm09.
Intriguingly, the effectiveness rose to 90% in a group of volunteers who were given an initial half dose, followed by a full dose. It's not clear why there is a difference.
这个有意思
福齐接受加拿大广播公司采访时说，开始预估70%有效，70%他就满意。 但是争先恐后出来2个，有效性90%，94%，95%，很意外，他说到底什么有效性要等运用后才知道。
脑回路感人
外行求科普，moderna太戏精，一直在操控股票
你为什么故意落下祖国100%有效的疫苗？安的什么心？
猜测是样本太小的噪声吧 实验组一共三十人感染 不知道里面多少是full dose 多少是half dose
100%有效的新闻link？
一种可能是这一组的样本太小，好像只有30个感染？另一种可能是打完第一针以后体内出现了大量对抗腺病毒载体的抗体，导致第二针效果不好。
反正感觉这个疫苗效果一般。。。第一组half-full dose的情况还需要更多的数据。
稍作改进有可能达到90%有效
The trial looked at two different dosing regimens. A half dose of the vaccine followed by a full dose at least one month apart was 90 per cent effective. A second regimen using two full doses one month apart was 62 per cent effective. The combined results showed an average efficacy rate of 70 per cent.
https://www.cbc.ca/news/world/vaccine-covid-19-astrazeneca-1.5812268
http://www.xinhuanet.com/fortune/2020-08/18/c_1126379222.htm
“灭活疫苗上市后，价格不会很高，预计几百块钱一针。如果打两针的话，价格应在1000块钱以内。”刘敬桢告诉记者，打一针疫苗，保护率大概是97%，抗体产生是缓慢的，像曲线一样在缓慢增长，一般情况下大概半个月可以达到能抵抗新冠病毒的水平；如果打两针疫苗，保护率能达到100%。 刘敬桢介绍，打第一针疫苗与第二针的时间间隔一般是28天，但特殊情况下可以同时打，左胳膊一针、右胳膊一针。一针疫苗剂量是4微克。
---------这种不需要间隔几个星期打第二针，而是可以左右胳膊同时各打一阵的优势，也算是秒杀西方疫苗了
夏天的时候英国这边的社区传播不够如火如荼 后来为了加快速度搞人体试验直接感染
不过好奇不是说也在巴西搞了么 这回包括巴西的数据么
太小看强大的祖国了。
我赌96%。
人不要脸，天下无敌！
中国的疫苗都是和外国实验室合作的，没那么容易作假
先把有效率公布了再秒杀好不？
国内风气咋都这样呀，大家都不在乎数据，动不动就秒杀
尤其是巴西，看着并不服中国。真要爆出来数据，还是可信的。
错！必须赶英超美，96%
70%和95%光看数字好像差别不大，但其实有质的不同。70%的保护率，打了疫苗后，感染病毒的概率降低到1/3，对新冠这种传染性强的病毒，保护作用很有限。而95%的保护率，将感染的概率降低到1/20。打了前面那个疫苗，你不能出去浪，还得躲在家里。后面那个，可以出去浪了。
flu shot没有这么高 1/3到1/2
According to a Feb. 21 CDC Morbidity and Mortality Weekly Report, the current influenza vaccine has been 45% effective overall against 2019-2020 seasonal influenza A and B viruses. Specifically, the flu vaccine has been 50% effective against influenza B/Victoria viruses and 37% effective against influenza A(H1N1)pdm09.
看他们的press release是包括巴西的数据的 https://www.astrazeneca.com/media-centre/press-releases/2020/azd1222hlr.html
看了下这位党委书记的简历，本科学自动化的，怪不得能说出这么没有常识的话。。。
这同时打两针的操作符合国内加班赶工的风气。而且人定胜天！
不明白左胳膊一针右胳膊一针跟就扎一针，剂量加倍有啥区别？为啥要挨两针？都一个胳膊这胳膊就废了么？
一般间隔两周打第二针是为了产生更强的免疫反应。
历害国书记让左右胳膊同时各打一针，巧妙利用空间上的距离代替了时间上的间隔，也算是一大创新吧！
左右胳膊各扎一针取代间隔28天，哈哈哈笑吐了
"抗体产生是缓慢的，像曲线一样在缓慢增长"
确定是自动化出生的？
看看这一句，我也是服气的。
就是啊，敢这么抹黑百分百疫苗！拉出去喝茶！
真的笑死，那腿也别拉下啊，还有俩腿呢
这个评论，我服气