Boise has a 228k population * 1.79% seroprevalence = 4080 estimated exposures. Ada County (in which Boise lies) has a 392k population, has had 663 recorded cases to date = 0.17% cumulative incidence, and has 17 recorded deaths = 2.6% CFR. As the rest of Ada County's incidence should lag Boise metro a good bit due to the ex-metro's lower population density and thus lower average Rt, Boise should account for more than its pro rata share of the county's covid burden. Let's say Boise accounts for 100 more than its 386 pro rata share of the county's 663 cases, and 3 more than its 10 pro rata share of the county's 17 deaths. 13 deaths out of Boise's 4080 serologically estimated exposures = 0.32% IFR. (That's about 8x lower than Ada County's CFR, which is roughly in line with the 10x differential between the cumulative reported case incidence and the detected seroprevalence). This is about half the estimated IFR using NYC's reported deaths and the recent serological survey there.
敏感性方面,在确诊病人症状出现十几天之后,可以说是百测百中,目前没有失过手。只要康复了有抗体了,可以说基本都能测出来,假阴性约等于不存在。
特异性方面,两次超千份大样本测试,一次假阳性仅为0.37%,一次假阳性仅为0.10%。
可以说只要测试地真阳率别太低,用Abbott家的抗体测试,结果应该会非常准确。
Idaho的Boise市(人口约23万)用了它家测试,测了4856人(全市总人口的2.1%),测出阳性87人,阳性率1.79%。
Boise市自己的病人情况没有报道,但是其所在的Ada County(人口约48万),目前有663名确诊病人,死亡17人,粗死率2.6%。
推算下来,Boise实际感染人数大概是核酸测量阳性者的8倍左右,粗死率能降到0.32%。
Boise has a 228k population * 1.79% seroprevalence = 4080 estimated exposures. Ada County (in which Boise lies) has a 392k population, has had 663 recorded cases to date = 0.17% cumulative incidence, and has 17 recorded deaths = 2.6% CFR. As the rest of Ada County's incidence should lag Boise metro a good bit due to the ex-metro's lower population density and thus lower average Rt, Boise should account for more than its pro rata share of the county's covid burden. Let's say Boise accounts for 100 more than its 386 pro rata share of the county's 663 cases, and 3 more than its 10 pro rata share of the county's 17 deaths. 13 deaths out of Boise's 4080 serologically estimated exposures = 0.32% IFR. (That's about 8x lower than Ada County's CFR, which is roughly in line with the 10x differential between the cumulative reported case incidence and the detected seroprevalence). This is about half the estimated IFR using NYC's reported deaths and the recent serological survey there.
https://www.fda.gov/media/137383/download
https://www.medrxiv.org/content/10.1101/2020.04.27.20082362v1
忘了说了,FDA已批准EUA
FDA抗体测试批了10种了已经
估计exclude的那位实际上是核酸测试的假阳者
这个抗体测试不适合早期测试的
几天前收到家庭医生邮件说可以开单测抗体。自负$55,蓝十字的ppo