最近一篇剑桥的文章引起五毛的轰动， 认为抓住了美国是新冠源头的重要证据。 我大概看了一下， 环球网基本上是指鹿为马。 论文基本有几个疑点。 希望有基因大牛指点一下 In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.
In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.
原作 https://www.pnas.org/content/early/2020/04/07/2004999117 Phylogenetic network analysis of SARS-CoV-2 genomes
环球洗地文 https://s3.uczzd.cn/webview/news?app=uc-iflow&aid=5373213927615713583&cid=10520&zzd_from=uc-iflow&uc_param_str=dndsfrvesvntnwpfgicp&recoid=16900807336239716824&rd_type=share&sp_gz=0&pagetype=share&btifl=100&uc_share_depth=1
原作的数据源 https://www.pnas.org/highwire/filestream/921144/field_highwire_adjunct_files/1/pnas.2004999117.sd01.xlsx、