回复1楼Czboy 不是疫苗。The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
China's health leadership announced they have found the Japanese-developed anti-influenza drug Avigan to be effective in treating COVID-19 disease patients.
Zhang Xinmin, China’s director of the National Center for Biotechnology Development said Avigan (Favipiravir) was found to be effective in 2 clinical trials completed in Wuhan and Shenzhen and involved 240 patients and 80 patients respectively.
During a conference in Beijing on March 17, 2020, Zhang said the medicine worked for coronavirus-related symptoms including pneumonia and had no obvious side effects.
Zhang said those who were given Avigan reported positive results after 4 days of therapy. This contrasts with a median of 11 days for those without the medication.
Zhang said more than 80 [url=https://www.coronavirustoday.com/2019-nCoV]COVID-19[/url] patients have participated in the clinical trial in The Third People's Hospital of Shenzhen, including 35 patients taking Favipiravir and 45 patients on a control group.
One of these clinical trials also found that X-rays confirmed improvements in lung conditions in about 91 percent of the patients who were given the medicine.
The director said he formally recommended the use of this medicine as a way to treat the COVID-19 disease, which is caused by the [url=https://www.coronavirustoday.com/SARS-Cov-2]SARS-CoV-2[/url] virus.
According to Zhang, a Chinese pharmaceutical company has been approved by the National Medical Products Administration to mass-produce the medication and ensure a stable supply.
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EvenOdd 发表于 3/18/2020 7:48:29 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2519774&postid=83192988#83192988][img][/img][/url]
Referring to below, why then this drug was approved at first, and has been used for sometime for other applications?
" S. Korea not to use Japan's Avigan as coronavirus drug 10:27 March 16, 2020
The Ministry of Food and Drug Safety said it has decided not to import Avigan after a team of infectious disease experts here ruled there is not enough clinical data to prove the drug's efficacy.
Avigan was approved as a backup drug for reemergent influenza in Japan in 2014. However, it has not been used to treat regular flu because several animal studies showed potential fetal damage.
"Avigan has not only not shown efficacy during test studies but also there is not data on clinical trials conducted on patients," said Oh Myoung-don, an infectious disease expert. "The drug has also shown serious side effects, such as fetal deaths in animal studies."
[url=https://time.com/5804092/experimental-covid-19-vaccine-test-begins-as-u-s-volunteer-receives-first-shot/]https://time.com/5804092/experimental-covid-19-vaccine-test-begins-as-u-s-volunteer-receives-first-shot/[/url] Monday’s milestone marked just the beginning of a series of studies in people needed to prove whether the shots are safe and could work. Even if the research goes well, a vaccine wouldn’t be available for widespread use for 12 to 18 months, said Dr. Anthony Fauci of the U.S. National Institutes of Health. That’s still important if the virus becomes a long-term threat. 也是有希望。
The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
回复1楼Czboy 不是疫苗。The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
回复 1楼Czboy的帖子 不是疫苗。The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects. Read more: https://metro.co.uk/2020/
The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
回复1楼Czboy 不是疫苗。The injections given will not contain coronavirus itself, and instead are filled with potential treatments to establish whether they could cause side-effects.
Monday’s milestone marked just the beginning of a series of studies in people needed to prove whether the shots are safe and could work. Even if the research goes well, a vaccine wouldn’t be available for widespread use for 12 to 18 months, said Dr. Anthony Fauci of the U.S. National Institutes of Health. That’s still important if the virus becomes a long-term threat.
🔥 最新回帖
请问一般临床一期二期需要多久啊？疫苗需要三期吗？为啥需要这么久才能上市呢？我知道FDA在这个特殊时候，速度很快的，应该不是瓶颈。
天，中国做疫苗就是正常，美国做就是阴谋。脑子都坏掉了啊！
你说这些川普都做了，你自己视而不见。你说那些障碍都是奥巴马留下的遗产。
Referring to below, why then this drug was approved at first, and has been used for sometime for other applications?
"
S. Korea not to use Japan's Avigan as coronavirus drug 10:27 March 16, 2020
[url=https://en.yna.co.kr/view/AEN20200316002400320]https://en.yna.co.kr/view/AEN20200316002400320[/url]
...
The Ministry of Food and Drug Safety said it has decided not to import Avigan after a team of infectious disease experts here ruled there is not enough clinical data to prove the drug's efficacy.
Avigan was approved as a backup drug for reemergent influenza in Japan in 2014. However, it has not been used to treat regular flu because several animal studies showed potential fetal damage.
"Avigan has not only not shown efficacy during test studies but also there is not data on clinical trials conducted on patients," said Oh Myoung-don, an infectious disease expert. "The drug has also shown serious side effects, such as fetal deaths in animal studies."
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🛋️ 沙发板凳
正常要好几年，如果一年算超级，如果phase 1 clinical 有非常好的效果，
那么很可能8个月完成
这种新闻才是疫情中最鼓舞士气的新闻。
川巨巨太反智，结果偏偏遇上公共健康卫生这么一个大的挑战。
这不是用股票和生意能解决的困境
这时候应该大力宣扬美国的科技实力、各种正在进行的临床实验攻关新冠、各种法规规定在特殊时期要为这一类的研究实验大开绿灯。
这样大家的信心才会一点点build up。
是啊，大家都不看内容，这个实验说白了什么都不是。
只是看看正常人会不会有不正常反应而已。
Ebola有疫苗。
God Bless America !
谁跟你说的？有Ebola基因片段你还能活到现在？
re，最近和大妈吵架吵得都说不出这么好的话了，感觉huaren 到处不同意川巨巨就是小粉红wm的那些大妈完全是来摧毁美国的
8个月是从什么时候开始算？
这个疫苗不用live virus，现在打得就是疫苗，phase one主要是分四个dose衡量安全性，但同时每隔几天也会测试抗体水平。有些特别有效的药物，在一期做完以后，在二期进行中就批准了。现在这个疫苗研制超快，我的希望如果确实安全有效，照这个速度8到10个月上市很有可能。
每隔三天测抗体水平
疫苗用的是假的S蛋白，用mRNA 技术deliver，这就是疫苗，根本不用virus live or dead， 当类似S蛋白进入人体后就会产生免疫抗体， 当病毒通过自己的S蛋白感染时，这个抗体就会阻挡这个过程。
没错，就是这样子的
是的，很多人缺乏这方面常识。
这个技术Moderna 遥遥领先，关键在于这个S蛋白的deliver能不能到位，这样才能激起免疫反应。
致敬！祝福！祈祷！！！
God Bless America！！！！！！！！！！！！！！！！
这倆可以同时上啊，反正板兰根也吃不坏，人早说是中西医结合了
中国政府其实等着疫苗和药救命呢
板蓝根好歹毒性小，没有有效药的时候安慰剂也很重要，否则很多人会吓死。害怕恐惧会降低免疫能力的。再说中药都是热汤，好歹能促进体液循环，这也很重要。
放心吧，人家会想办法偷，然后说他自己也造出来了。
不太理解这个，为什么二期需要找患者接受实验？疫苗不是为了预防吗？找患者做疗效实验的就该是治疗的药物吧。
谁来解释下，二期三期实验需要把志愿者暴露在活性病毒里验证预防作用吗？
已经生病了再打疫苗？？
同疑问，为什么要找患者实验？不make sense啊
还是看不明白，您只要说到底这疫苗是有效还是心理安慰剂。
他们的名字应该给更多人看到， 而且应该写下来也留给后人纪念。
疫苗会促使人的免疫系统产生记忆抗体，当然是疫苗，心理安慰剂有何用？
我报了没理我 估计很多人报
谢科普
患者测试疫苗意义何在？
不需要widespread use, 只要对高危人群可用，就可以极大的减少恐慌。
赞👍专业。谢谢🙏
Based on your experience, which company is more likely to first create a successful vaccine? Maybe we should buy their stocks? Thanks!
想到一起了