楼主贴的也是说副作用，感觉这个“柒”张嘴就来，我查了一下Ebola临床报告，关于Remdesivir有如下描述： In the initial study, infected animals treated with 3 to 10 mg/kg of remdesivir administered once daily by IV injection for 12 days beginning 3 days post Ebola virus inoculation exhibited 100% survival combined with a significant suppression of EVD clinical symptoms including amelioration of behavioral depression, changes in hematology and coagulation parameters, as well as serum chemistry markers of kidney and liver toxicity, and no signs of drug-related toxicities.
楼主贴的也是说副作用，感觉这个“柒”张嘴就来，我查了一下Ebola临床报告，关于Remdesivir有如下描述： In the initial study, infected animals treated with 3 to 10 mg/kg of remdesivir administered once daily by IV injection for 12 days beginning 3 days post Ebola virus inoculation exhibited 100% survival combined with a significant suppression of EVD clinical symptoms including amelioration of behavioral depression, changes in hematology and coagulation parameters, as well as serum chemistry markers of kidney and liver toxicity, and no signs of drug-related toxicities.
楼主贴的也是说副作用，感觉这个“柒”张嘴就来，我查了一下Ebola临床报告，关于Remdesivir有如下描述： In the initial study, infected animals treated with 3 to 10 mg/kg of remdesivir administered once daily by IV injection for 12 days beginning 3 days post Ebola virus inoculation exhibited 100% survival combined with a significant suppression of EVD clinical symptoms including amelioration of behavioral depression, changes in hematology and coagulation parameters, as well as serum chemistry markers of kidney and liver toxicity, and no signs of drug-related toxicities.
机理上说得通的东西可多了，实验上各种啪啪打脸，人对生物机理的了解如同盲人摸象。当然了，总比双黄连靠谱
太搞笑了吧，发帖的目的是想了解Remdesivir，跟双黄连有啥关系。现在trial的还有其他药物，如果你看看新闻就知道，Lopinavir，Ritonavir，实事求是一点不行吗？
kaletra呢，这个似乎浙江用是哦想过不错，为啥没听武汉那边用啊
还有那个俄罗斯药也被那个院士推，其实一点用都没有，机理都不对
新闻说Gilead还要等三个星期才能出数据，感觉黄花菜都要凉了。不过可能也没办法，做实验就得这样。还是希望能有好的结果吧。
楼主贴的也是说副作用，感觉这个“柒”张嘴就来，我查了一下Ebola临床报告，关于Remdesivir有如下描述：
In the initial study, infected animals treated with 3 to 10 mg/kg of remdesivir administered once daily by IV injection for 12 days beginning 3 days post Ebola virus inoculation exhibited 100% survival combined with a significant suppression of EVD clinical symptoms including amelioration of behavioral depression, changes in hematology and coagulation parameters, as well as serum chemistry markers of kidney and liver toxicity, and no signs of drug-related toxicities.
对人类副作用也没有提及，只能等这次临床试验。
临床报告不会说animal吧
这个药phase III做过了在刚果ebola的病人做的，毒性测过没有什么问题但是ebola效果一般没有批，这次临床是要测冠状病毒的效果，希望能过吧，这样美国爆发大家还能吃上。
因为Gilead本身要受美国法律的管控，必须一步步走，但这一点都不妨碍五毒所抢注专利，也不影响国内复制药的热情
https://www.who.int/ebola/drc-2018/summaries-of-evidence-experimental-therapeutics.pdf?ua=1
1期报告里面提及的，当然1期已经是上人了，应该是包括了preclinical数据
Wiki的不能算可靠来源。看看别的吧
同求，半年内ID, 同时要屏掉发帖少500的ID.😫歪哥
好像是的。小道消息听说这个药在国内临床实验进展并不顺利 还有中央领导大量囤药
江苏那边的仿制药已经做好了
赶紧的，让中国退货，让Gilead吃屎去