Which labs are affected: State labs that have been successful in verifying the test kit works can go forward with the testing. Those that haven’t been successful will have to wait for the CDC to ship out the replacement components. The CDC did not confirm how many states were affected or when they might receive the replacement components.
Chin Med J (Engl). 2020 Feb 7. doi: 10.1097/CM9.0000000000000744. [Epub ahead of print] Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Kui L1, Fang YY1, Deng Y1, Liu W2, Wang MF3, Ma JP4, Xiao W5, Wang YN6, Zhong MH7, Li CH8, Li GC9, Liu HG1. Author information Abstract BACKGROUND: A novel coronavirus (2019-nCoV) causing an outbreak of pneumonia in Wuhan, Hubei province of China was isolated in January 2020. This study aims to investigate its epidemiologic history, and analyzed the clinical characteristics, treatment regimens, and prognosis of patients infected with 2019-nCoV during this outbreak. METHODS: Clinical data from 137 2019-nCoV-infected patients admitted to the respiratory departments of nine tertiary hospitals in Hubei province from December 30, 2019 to January 24, 2020 were collected, including general status, clinical manifestations, laboratory test results, imaging characteristics, and treatment regimens. RESULTS: None of the 137 patients (61 males, 76 females, aged 20-83 years, mean age 55 ± 16 years) had a definite history of exposure to Huanan Seafood Wholesale Market. Major initial symptoms included fever (112/137, 81.8%), coughing (66/137, 48.2%), and muscle pain or fatigue (44/137, 32.1%), with other, less typical initial symptoms observed at low frequency, including heart palpitations, diarrhea, and headache. Nearly 80% of the patients had normal or decreased white blood cell counts, and 72.3% (99/137) had lymphocytopenia. Lung involvement was present in all cases, with most chest computed tomography scans showing lesions in multiple lung lobes, some of which were dense; ground-glass opacity co-existed with consolidation shadows or cord-like shadows. Given the lack of effective drugs, treatment focused on symptomatic and respiratory support. Immunoglobulin G was delivered to some critically ill patients according to their condition. Systemic corticosteroid treatment did not show significant benefits. Notably, early respiratory support facilitated disease recovery and improved prognosis. The risk of death was primarily associated with age, underlying chronic diseases, and median interval from the appearance of initial symptoms to dyspnea. CONCLUSIONS: The majority of patients with 2019-nCoV coronavirus pneumonia present with fever as the first symptom, and most of them still showed typical manifestations of viral pneumonia on chest imaging. Middle-aged and elderly patients with underlying comorbidities are susceptible to respiratory failure and may have a poorer prognosis. 这是最新的文章，没有全文，不知道死亡率
U.S. Northern Command is executing plans to prepare for a potential pandemic of the novel coronavirus, now called COVID19, according to Navy and Marine Corps service-wide messages issued this week. An executive order issued by the Joint Staff and approved by Defense Secretary Mark Esper this month directed Northern Command and geographic combatant commanders to initiate pandemic plans, which include ordering commanders to prepare for widespread outbreaks and confining service members with a history of travel to China. The Navy and Marine Corps messages, issued Tuesday and Wednesday, respectively, reference an executive order directing U.S. Northern Command to implement the Department of Defense Global Campaign plan for Pandemic Influenza and Infectious Diseases 3551-13. The document serves as the Pentagon’s blueprint for planning and preparing for widespread dispersion of influenza and previously unknown diseases. U.S. Northern Command said Wednesday it was directed the Joint Staff Feb. 1 to commence “prudent planning” in their assigned role synchronizing the department’s plans for pandemic flu and disease.
The US Centers for Disease Control and Prevention said on Wednesday that it’s remaking parts of coronavirus test kits because some produced inconclusive test results. The CDC had sent kits to states to speed up testing. For quality control, the states then had to verify that the kits worked before testing patients -- but some kits returned inconclusive results during this verification process. Some states said the results they were getting weren’t false negatives or false positives, but were inconclusive, said the CDC. So it's remaking the one reagent in the test that is not performing consistently. Which labs are affected: State labs that have been successful in verifying the test kit works can go forward with the testing. Those that haven’t been successful will have to wait for the CDC to ship out the replacement components. The CDC did not confirm how many states were affected or when they might receive the replacement components. “During a response like this we know things may not go as smoothly as we would like,” said Nancy Messonnier, director of the National Center for Immunization and Respiratory Diseases. “We have multiple levels of quality control to detect issues just like this one. We’re looking into all of these issues to understand what went wrong, and to prevent these same things from happening in the future.”
Another 44 people have tested positive for the novel coronavirus aboard the Diamond Princess cruise ship docked in Yokohama, Japanese health minister Katsunobu Kato said on Thursday. This bring the total number of cases on the ship to 219, including one Japanese quarantine officer -- the largest outbreak of the virus outside of mainland China.
Another 44 people have tested positive for the novel coronavirus aboard the Diamond Princess cruise ship docked in Yokohama, Japanese health minister Katsunobu Kato said on Thursday.
This bring the total number of cases on the ship to 219, including one Japanese quarantine officer -- the largest outbreak of the virus outside of mainland China. fish_fish 发表于 2/12/2020 11:15:14 PM
Another 44 people have tested positive for the novel coronavirus aboard the Diamond Princess cruise ship docked in Yokohama, Japanese health minister Katsunobu Kato said on Thursday.
This bring the total number of cases on the ship to 219, including one Japanese quarantine officer -- the largest outbreak of the virus outside of mainland China. fish_fish 发表于 2/12/2020 11:15:14 PM
size=0.22]专家：重症病人的血液和粪便中也发现病毒
[size=0.12]湖北省发布会 2020-02-13 21:43:44[size=0.12]查看全文
[size=0.19]广州支援武汉协和医院医疗队队长、广州医科大学附属第一医院副院长张挪富在发布会上表示，ICU里面重症病人大概有60%以上的病人，上下呼吸道都能够检出病毒，而且病毒载量非常高，除了呼吸道之外，在重症血液、粪便中也找到了病毒，有可能出现其他传播途径。
44 more people just tested positive for coronavirus on the Diamond Princess cruise shiphttps://www.cnn.com/asia/live-news/coronavirus-outbreak-02-13-20-intl-hnk/index.html
Which labs are affected: State labs that have been successful in verifying the test kit works can go forward with the testing. Those that haven’t been successful will have to wait for the CDC to ship out the replacement components. The CDC did not confirm how many states were affected or when they might receive the replacement components.
[size=0.19]12日，湖北省卫健委官网，除公布疑似病例、确诊病例，首次公布新冠肺炎临床诊断病例具体数字。
[size=0.19]记者了解到，通报临床诊断病例是与最新版的《新型冠状病毒感染的肺炎诊疗方案》相适应，临床诊断病例可参照确诊病例治疗。
[size=0.19]据悉，截至2020年2月11日24时，湖北省当日新增临床诊断病例4890例，现有临床诊断病例10567例；疑似病例、临床诊断病例集中隔离15514人。
[size=0.19]- 01 -
[size=0.19]疑似病例拍CT符合症状
[size=0.19]没有核酸检测也确定为临床诊断病例
[size=0.19]武汉大学健康学院全球健康系主任向浩分析，公布临床诊断病例，应该是根据《新型冠状病毒感染的肺炎诊疗方案（试行第五版）》的要求。这一版的诊疗方案在病例诊断上，将湖北省和湖北省以外其他省份进行了区分。
[size=0.19]湖北以外其他省份仍然分为“疑似病例”和“确诊病例”两类，湖北省增加“临床诊断”分类。
[size=0.19]并且，湖北省“疑似病例”标准放宽：只要符合
[size=0.19]“发热和/或呼吸道症状”
[size=0.19]“发病早期白细胞总数正常或降低，或淋巴细胞计数减少”
[size=0.19]这两条临床表现，便可考虑为疑似病例。疑似病例只要具有肺炎影像学特征者，为临床诊断病例。
[size=0.19]向浩解释，这意味着，疑似病例只要拍CT，有新冠肺炎肺部病变的特征，在没有核酸检测的情况下，就成为临床诊断病例。
[size=0.19]- 02 -
[size=0.19]临床诊断病例去哪里 怎么治
[size=0.19]集中隔离点或定点医院
[size=0.19]记者从武汉市卫健委获悉，临床诊断病例治疗方案等同于确诊患者的治疗方案。
[size=0.19]据悉，按照第五版诊疗方案，各级各类医疗机构的医护人员发现疑似病和临床诊断病例后，应该立即进行隔离治疗，疑似病例和临床诊断病例要单间隔离，对疑似病例和临床诊断病例要尽快采集标本进行病原学检查。
[size=0.19]按照省市疫情防控指挥部的要求，疑似患者集中隔离，无法明确排除新冠肺炎的发热患者、疑似患者等在集中隔离点集中隔离、治疗观察。而定点医院目前抢救重症、危重症患者和疑似危重症患者，
[size=0.19]根据这一要求，临床诊断病例应该先去集中隔离点，达到重症或危重症就应去定点医院。进一步病原学检查，即核酸检测后，如果确诊为轻症，应去方舱医院。
[size=0.19]- 03-
[size=0.19]对诊断治疗环节的完善
[size=0.19]不会大幅增加新增病例
[size=0.19]公布新冠肺炎临床诊断病例有何意义，后期的防控举措会有相应的调整吗？
[size=0.19]华中科技大学同济医学院医药卫生管理学院院长冯占春教授介绍，新冠肺炎是一种新发传染病，对疾病的认识还在不断深化，其诊断标准和治疗方案也在不断完善当中。
[size=0.19]湖北武汉是重灾区，有大量的疑似病例需要做核酸检测确诊。由于核酸试剂盒供应及检测能力受限，且一定比例的新冠肺炎患者存在核酸检测阴性的情况，不少一线医生呼吁把CT影像学特征作为确诊的标准，以加快患者的确诊速度，尽快将确诊患者收治入院规范治疗。
[size=0.19]国家正是考虑了湖北和武汉的实际，在新冠肺炎诊疗方案第五版增加了临床诊断病例，对疑似病例中具有明显的肺炎影像学特征的作为临床诊断病例，立即进行隔离治疗，减少病情延误，最大限度控制传染源，阻断传播途径。
[size=0.19]临床诊断病例主要是对诊断治疗环节的完善。经过前期的摸索，湖北武汉近期出台的政策和措施越来越符合疫情控制的实际。
[size=0.19]截至2020年2月11日24时，湖北省累计报告新冠肺炎病例33366例，而现有临床诊断病例就达到10567例。通报的新冠肺炎临床诊断病例数还较大，是否说明新增确诊病例数还会有较大攀升？
[size=0.19]冯占春认为，临床诊断病例前期就属于疑似病例，当中具有肺炎影像学特征的患者，将其单列出来尽早隔离治疗，只是加快了患者规范治疗的速度，减少了排队等确诊后再治疗，对控制整个疫情发展是有利的，并不意味着新增病例会大幅增长。
[size=0.19]武汉市卫生健康委温馨提示：
[size=0.19]火神山医院不设门诊，请市民朋友不要自行前往火神山医院看病。
[size=0.19]来源 |武汉晚报微信公众号
[size=0.19]编辑 | 王珊
太惨了，日本人是不是拿错试剂盒了
Re
我看新闻报导说有慢性病的带的药没了，要求了好几次，后来打横幅求救。
日本的药品供应暂时也没跟上。 不知道怎么搞得这么乱。
很有可能
这样不行，尽管不知道病毒是怎么传播的，明显还在传播。借试剂盒也得全部测试，让阴性的人下船隔离，确诊的人进医院。不然一不小心又是一个小武汉。
怎么接，除了走水路，其他的途径都需要日本地面人员配合，基本上各国撤侨都是飞机首选。日本现在还是不肯让游轮上的人“登陆”，只接出阳性的人。
测试了是阴性的人呢？测出是阴性的就该让人家走，要不然呆在船上有又被传染的可能
已经开始允许下船了。80岁以上和內舱的人先测试，结果是阴性就可以下船了。
呆着，继续隔离，因为这个人可能接触了新的阳性的人，所以还是在潜伏期。
好消息，日本政府总算松动了。
是的，但是游轮按计划访问日本，已经进港，乘客里一半是日本人。
这船上一半乘客是日本人。
那是后面一艘，这艘好像是已经进港了，而且按计划也是要访问日本的，第一个病例是香港来的老人。上面那些日本人等于是游了一圈，按原计划是要回家。
终于反应过来了。
不是，是为了尽量控制传染源。以前用核酸标准，很多传染源都散布在社区中，达不到防疫的目的。
不过看今天的数字，还是不乐观。急呀。