柳叶刀上的英文全文,有兴趣的可以看 [url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736]https://www.thelancet.com/journals/lancet/article/PIIS0140-6736[/url](20)30183-5/fulltext By Jan 2, 2020, 41 admitted hospital patients had been identified as having laboratory-confirmed 2019-nCoV infection. Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular disease (six [15%]). Median age was 49·0 years (IQR 41·0–58·0). 27 (66%) of 41 patients had been exposed to Huanan seafood market. One family cluster was found. Common symptoms at onset of illness were fever (40 [98%] of 41 patients), cough (31 [76%]), and myalgia or fatigue (18 [44%]); less common symptoms were sputum production (11 [28%] of 39), headache (three [8%] of 38), haemoptysis (two [5%] of 39), and diarrhoea (one [3%] of 38). Dyspnoea developed in 22 (55%) of 40 patients (median time from illness onset to dyspnoea 8·0 days [IQR 5·0–13·0]). 26 (63%) of 41 patients had lymphopenia. All 41 patients had pneumonia with abnormal findings on chest CT. Complications included acute respiratory distress syndrome (12 [29%]), RNAaemia (six [15%]), acute cardiac injury (five [12%]) and secondary infection (four [10%]). 13 (32%) patients were admitted to an ICU and six (15%) died. Compared with non-ICU patients, ICU patients had higher plasma levels of IL2, IL7, IL10, GSCF, IP10, MCP1, MIP1A, and TNFα.
llsun 发表于 1/25/2020 7:37:56 AM [url=https://forums.huaren.us/showtopic.aspx?topicid=2495887&postid=82501243#82501243][img][/img][/url]
1月 10日的时候,就有 xu jianguo 开了学术会议,已经从59个病例中的15个病人中分离出新冠状病毒,但是他提到了是否公布得由多个ZF机构决定。 Q: The 5 January report from the Wuhan Municipal Health Commission, the latest available, says a total of 59 pneumonia patients have been identified as possibly carrying the virus. Have more patients been found? A: It should be mentioned that the 59 reported pneumonia patients in Wuhan were clinically diagnosed; of those, 15 were confirmed to be infected by the new coronavirus. No new patients have appeared, as far as I understand. It’s good news. People fear something like SARS in 2003, but this is a different case. The outbreak is limited, but we should test patients one by one [to identify] pneumonia caused by other pathogens [url=https://www.sciencemag.org/news/2020/01/mystery-virus-found-wuhan-resembles-bat-viruses-not-sars-chinese-scientist-says]https://www.sciencemag.org/news/2020/01/mystery-virus-found-wuhan-resembles-bat-viruses-not-sars-chinese-scientist-says[/url]
大实话
一个多月的时间太短了,国内外那么多专家都开始发表论文,仅仅是个开始。致病原因是个很严肃的科学问题,并不是“群情激愤”就能搞清楚的。
土工的决策层基本都是老年人,就算土工真脑残到这个地步就不怕病毒反噬,还是他们都有李大师的法力保护刀枪不入?
实验室制造出来的病毒,还有谁有能力投放
制造混乱开始帅锅,维持统治,可怜的永远是底层老百姓
哈哈,认真你就输了
哈哈哈
管他呢,都是土共的错
看了 不寒而栗
武汉的地理位置 全国中心交通枢纽
春运高峰
时间点地点不可能更完美
一切都觉得make sense了
看了 不寒而栗
看下地图武汉的地理位置 全国中心交通枢纽
春运高峰
时间点地点不可能更完美
一切都觉得make sense了
发觉了,很多浑水摸鱼的
同意ls的,需要多测序这次的病毒,可以倒推出patient 0出现的时间
目前看泰国的病人和武汉的初始病人之间没有任何mutation
我没有经历过sars1.0,班上好多人说这次没上次严重或者上次和这次情况很不同什么的,
看一下这篇关于sars1.0的科普 https://harvardmagazine.com/2007/03/the-sars-scare.html
很多情况和这次很类似,比如很多人是无症状传播者
显然是李大师乏力无变
但是实验室有哪些实验和病毒有记录的吧
但是丁香还是哪儿也有文章说在市场取样了然后找到一些线索,不知道是不是因为他是港大的所以不给他而已。
管轶:我吃了不少闭门羹,愿意合作的科研机构并不多。他们管理很惯性,也许认为自己更有能力。 但关键一点我想指出,当时华南海鲜市场封掉,洗地,“犯罪现场”都没了,没有证据怎么破案啊。追溯动物源是个比较复杂的过程,我不可能随便找到一个带有病毒的动物就把它归咎是元凶,需要规模和体系等科学分析。
放心吧,人家早就有疫苗了
研究所研究病毒是很正常的。因为某种原因,是用完了垃圾公司没按规矩销毁转卖给野味市场,还是根本在买的时候就出了问题,实验用动物被倒卖进了海鲜市场导致病毒传染。就是一次事故。所以这次的反应才会这么诡异。先报道了有肺炎。又抓了八个人。这八个人传的是什么谣言,是不是某种关于内情的谣言。然后这么大的疫情,没有说要追查责任,中央没一个常委愿意出来说话或者做主。也不来看望灾区人民,也不提这事。说明是各派都想这事过去,谁也不愿插手。
研究所归中科院管,研究所出事故未必报的是湖北政府,它上面的机构跟湖北沟通不知道又如何。湖北政府可能还觉得冤枉呢,你放一个病毒研究所在我这出了事我最惨。这次闹了这么久,居然中央一没有封了全国的野味市场,二没有震怒,三没有撤掉整个湖北官场估计就是这个原因,湖北说不是我的责任。确实也不完全是。现在就是闹得太大斬几个人头平息一下民众。
感觉就像美国那些生化电影,某研究所出了车祸导致病毒泄露,或者什么实验动物逃了(outbreak) 然后大家就逃吧,最后靠某些有良知的超级医生救大家。
我现在觉得,之前那些专家说可放可控应该是有某些原因的,他们可能知道点内情,真的以为可放可控。但是病毒的演化超出了他们的想象。不过呢,确实如钟南山所说,大家全在家两周这病就过去了。没有新的感染,旧的绝大多数自愈。
1月 10日的时候,就有 xu jianguo 开了学术会议,已经从59个病例中的15个病人中分离出新冠状病毒,但是他提到了是否公布得由多个ZF机构决定。
Q: The 5 January report from the Wuhan Municipal Health Commission, the latest available, says a total of 59 pneumonia patients have been identified as possibly carrying the virus. Have more patients been found? A: It should be mentioned that the 59 reported pneumonia patients in Wuhan were clinically diagnosed; of those, 15 were confirmed to be infected by the new coronavirus. No new patients have appeared, as far as I understand. It’s good news. People fear something like SARS in 2003, but this is a different case. The outbreak is limited, but we should test patients one by one [to identify] pneumonia caused by other pathogens
[url=https://www.sciencemag.org/news/2020/01/mystery-virus-found-wuhan-resembles-bat-viruses-not-sars-chinese-scientist-says]https://www.sciencemag.org/news/2020/01/mystery-virus-found-wuhan-resembles-bat-viruses-not-sars-chinese-scientist-says[/url]
个人猜测,专家最初就是觉得人传人的概率低的,我同学作为专家组成员一月初就到武汉了,不能说不重视,从lancet的文章看,当初的病例的确没有明显的家族聚集性,这可能是最初决策不坚定的原因吧,但一月中旬病例爆发性增长,以往SARS的教训,加上远超sars的传染性,就出现了前所未有的紧张,才有了后来的封城,至于早期政府的不作为、不协同,导致形势混乱,肯定存在,但目前看来病毒没有SARS严重,希望大家真的响应钟南山号召,趁着春节放假,自我隔离保护,有发热症状先自检,如果是鼻塞流涕等感冒症状,在家休息观察,如果有气喘、呼吸困难、老年人有既往心肺病史,要及时就医
那我们与其寄口罩,不如寄test kit吧,这种rt pcr的采样从哪儿取?唾液?口腔swab?
听到的一种说法是在疾控检疫部门去海鲜市场查之前那些卖野生动物的商贩已经跑掉了,而且把野生动物销毁了,所以没法查。
有效的test kit做出来了吗,rt pcr都是血样检测吧
有道理的
隔壁昨晚贴的patient 0没去过海鲜市场的paper有香港媒体报了
[url=https://rd2.huaren.us/huaren.php?hrtopic_id=2495887&hrurl=https%3a%2f%2ftwitter.com%2fl0gg0l%2fstatus%2f1221172802008616961%3fs%3d21]https://twitter.com/l0gg0l/status/1221172802008616961?s=21[/url]
宇宙重启。。。。
这种人还不少
要等到病毒进入血液了,恐怕已是很晚的阶段了
强大的p4实验室.....感觉吃了苍蝇一样
非典的原因是什么呀?