The trial was conducted in healthy adults 18 to 59 years of age.
………、
The most common side effects were tenderness and pain after the first dose. Systemic side effects were less common, but were headache, fatigue and myalgia (achiness). There were generally more side effects reported after the second dose, although all were less than or equal to Grade 1. They lasted less than two days.
While the rate of unexpected side effects was similar between the vaccine and placebo groups, there was a slight imbalance of some reactions in the vaccine group to those who received a placebo. The vaccine group reported 15 cases of “embolic and thrombotic events,” or blood clots, among 14 recipients, compared with 10 in the placebo group.
Volunteers reported mild reactions such as injection site pain, headaches and fatigue, but there also were a number of blood clots in the vaccine group including one in a 25-year-old man with no prior medical history who needed surgery.
FDA said data is insufficient at this time to determine whether the vaccine caused or contributed to those events — especially because many of the people who experienced clotting had other risk factors. The agency said it “will recommend surveillance for further evaluation of thromboembolic events with deployment of the vaccine into larger populations.”
Johnson & Johnson said it did not consider the clotting events to be linked to the vaccine, since the rate of cases in the trial was similar to the frequency at which the cases occur in the general population.
but the numbers were so small (15 vs. 10 for blood clots, 6 vs. 0 for tinnitus), that FDA concluded "data at this time are insufficient to determine a causal relationship between these events and the vaccine."
The vaccine showed 42.3 percent overall efficacy in people over 60 with other health risks — such as obesity, heart problems and high blood pressure — which is lower than the FDA’s 50 percent bar for authorization.
听说jj很难约，不知道是否因为其安全性
腺病毒载体引起血凝问题，在过去二十年间一直没解决。
以往都是个体、或小规模接种，对受者密切监视，及时治疗，真正案发的不多。
现在大规模接种，根本没有相应的监管体系，后果不堪设想。
不要以为目前只有AZ疫苗被声讨，其它腺病毒疫苗也有案例发生，只不过被大数据“消除”了。
俺不是危言耸听，请自已放狗去查：腺病毒载体 血栓
如果对mRNA 疫苗的安全性质疑，那么机理更复杂的腺病毒载体疫苗岂不是毛病更多？
不要被jj防重症的话所蒙蔽，别的不行，才拿这个说事儿
对mRNA疫苗而言，优点太多了，防重症根本不值一提，连轻症都没有几个，扯啥重症、病死啊。
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041451
https://www.researchgate.net/publication/256200641_Matrix-M_adjuvant_Enhancing_immune_responses_by_%27setting_the_stage%27_for_the_antigen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899102/
https://pubmed.ncbi.nlm.nih.gov/29594879/
副作用，来自一、二期临试
https://www.biospace.com/article/novavax-s-covid-19-vaccine-shows-promise-in-phase-i/
The trial was conducted in healthy adults 18 to 59 years of age.
………、
The most common side effects were tenderness and pain after the first dose. Systemic side effects were less common, but were headache, fatigue and myalgia (achiness). There were generally more side effects reported after the second dose, although all were less than or equal to Grade 1. They lasted less than two days.
年过花甲的，別等了，赶紧打别的苗吧
https://www.cnbc.com/2021/02/24/covid-vaccine-these-are-the-most-common-side-effects-from-jjs-.html
While the rate of unexpected side effects was similar between the vaccine and placebo groups, there was a slight imbalance of some reactions in the vaccine group to those who received a placebo. The vaccine group reported 15 cases of “embolic and thrombotic events,” or blood clots, among 14 recipients, compared with 10 in the placebo group.
https://www.politico.com/news/2021/02/24/fda-johnson-johnson-single-dose-shot-covid-471327
Volunteers reported mild reactions such as injection site pain, headaches and fatigue, but there also were a number of blood clots in the vaccine group including one in a 25-year-old man with no prior medical history who needed surgery.
FDA said data is insufficient at this time to determine whether the vaccine caused or contributed to those events — especially because many of the people who experienced clotting had other risk factors. The agency said it “will recommend surveillance for further evaluation of thromboembolic events with deployment of the vaccine into larger populations.”
Johnson & Johnson said it did not consider the clotting events to be linked to the vaccine, since the rate of cases in the trial was similar to the frequency at which the cases occur in the general population.
but the numbers were so small (15 vs. 10 for blood clots, 6 vs. 0 for tinnitus), that FDA concluded "data at this time are insufficient to determine a causal relationship between these events and the vaccine."
https://twitter.com/rnaianalyst/status/1378086477171675140?s=21
https://www.politico.com/news/2021/02/24/fda-johnson-johnson-single-dose-shot-covid-471327
The vaccine showed 42.3 percent overall efficacy in people over 60 with other health risks — such as obesity, heart problems and high blood pressure — which is lower than the FDA’s 50 percent bar for authorization.
真搞不懂，有些人为啥坚持要打jj。
但我现在还不确定打P 或M 到底有何长期副作用？对我们40+和孩子们有什么长期影响？
如果现在奔六了，也就算了，现在这个年龄上不上下不下的，还想多活几年 ：）