A study released in September 2020 indicated that gargling with a saline-based solution can reduce viral load in COVID-19, and another released in 2021 suggested that saline works multiple ways to reduce cold symptoms related to infection with other coronaviruses and might work as well as a first-line intervention for COVID-19.
this time
"We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls“
“What excited some people about it is the fact that it’s very similar to a lot of vaccines produced in the past,” Swartzberg said. “Protein vaccines have been used for decades. For some people, that gives them a degree of comfort, based upon emotion and not science.”
Novavax has the potential to offer longer, broader protection than current mRNA vaccines, Dr. Michael Osterholm, director of the University of Minnesota’s Center for Infectious Disease Research and Policy (CIDRAP), told Fortune.
But more data on the vaccine is needed to determine the length of protection it offers, as well as its performance against Omicron subvariants.
“I think it could be a better vaccine,” Osterholm said, though he cautioned that, in the early days of mRNA COVID vaccines, society had “unbridled expectations that ultimately didn’t pan out,” such as the vaccines preventing infection.
Like mRNA vaccines, Novavax protects against severe COVID outcomes like hospitalization and death. But it doesn’t prevent infection or transmission, according to Yale Medicine.
Maryland-based Novavax began developing its COVID vaccine in 2020, during Operation Warp Speed, but manufacturing difficulties slowed progress. Countries began granting the vaccine approval in November.
In the U.S., the two-dose shot series is approved for those 12 and older, with shots occurring three to eight weeks apart. Side effects are similar to mRNA COVID vaccines and include tenderness, pain, and/or swelling at the injection site, fatigue, muscle pain, joint pain, headache, nausea, vomiting, and/or fever, according to Yale Medicine. As is the case with mRNA COVID vaccines, myocarditis—a rare form of heart inflammation—has been reported, though rarely.
Dr. Bali Pulendran, professor of microbiology and immunology at Stanford University, told Fortune he isn’t sure why the U.S. hasn’t yet approved Novavax for use as a booster, giving those who’ve received a two-dose mRNA series another option, aside from newly approved Omicron mRNA vaccines.
The U.S. Food and Drug Administration didn’t immediately respond to Fortune’s question as to why the U.S. hasn’t approved the vaccine for use as a booster, though other countries have.
“It’s a terrific vaccine, and I do hope people get access to it if they wish to,” Pulendran said.
A study released in September 2020 indicated that gargling with a saline-based solution can reduce viral load in COVID-19, and another released in 2021 suggested that saline works multiple ways to reduce cold symptoms related to infection with other coronaviruses and might work as well as a first-line intervention for COVID-19.
this time
"We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls“
https://www.news-medical.net/news/20220913/Saline-nasal-irrigation-after-COVID-19-diagnosis-reduces-hospitalization.aspx
盐水洗洗，挺好。
哈哈，疫苗一族情何以堪。
我打了血压要高2个月。
https://fortune.com/well/2022/09/17/america-skeptical-novavax-popular-abroad-covid-vaccine-covid19-omicron-booster-coroanvirus-pandemic-epidemic-endemic-cdc-fda/
“What excited some people about it is the fact that it’s very similar to a lot of vaccines produced in the past,” Swartzberg said. “Protein vaccines have been used for decades. For some people, that gives them a degree of comfort, based upon emotion and not science.”
Novavax has the potential to offer longer, broader protection than current mRNA vaccines, Dr. Michael Osterholm, director of the University of Minnesota’s Center for Infectious Disease Research and Policy (CIDRAP), told Fortune.
But more data on the vaccine is needed to determine the length of protection it offers, as well as its performance against Omicron subvariants.
“I think it could be a better vaccine,” Osterholm said, though he cautioned that, in the early days of mRNA COVID vaccines, society had “unbridled expectations that ultimately didn’t pan out,” such as the vaccines preventing infection.
Like mRNA vaccines, Novavax protects against severe COVID outcomes like hospitalization and death. But it doesn’t prevent infection or transmission, according to Yale Medicine.
Maryland-based Novavax began developing its COVID vaccine in 2020, during Operation Warp Speed, but manufacturing difficulties slowed progress. Countries began granting the vaccine approval in November.
In the U.S., the two-dose shot series is approved for those 12 and older, with shots occurring three to eight weeks apart. Side effects are similar to mRNA COVID vaccines and include tenderness, pain, and/or swelling at the injection site, fatigue, muscle pain, joint pain, headache, nausea, vomiting, and/or fever, according to Yale Medicine. As is the case with mRNA COVID vaccines, myocarditis—a rare form of heart inflammation—has been reported, though rarely.
Dr. Bali Pulendran, professor of microbiology and immunology at Stanford University, told Fortune he isn’t sure why the U.S. hasn’t yet approved Novavax for use as a booster, giving those who’ve received a two-dose mRNA series another option, aside from newly approved Omicron mRNA vaccines.
The U.S. Food and Drug Administration didn’t immediately respond to Fortune’s question as to why the U.S. hasn’t approved the vaccine for use as a booster, though other countries have.
“It’s a terrific vaccine, and I do hope people get access to it if they wish to,” Pulendran said.
而两者，本来是要是用在副作用较低的条件下。作为衡量医疗手段的效果衡量标准。
在副作用未知，副作用比较大的情况下。需要使用全员全因死亡率。
不过就这一点，洗鼻子，要比mRNA安全多了，基本上，逻辑上可以判断，没有严重副作用。因此，医疗可以用简单的降低N倍，或者efficacy表述。
MRNA等新的疫苗，药物。实际上只谈efficacy，什么降低N倍，都是忽悠人的。因为他们的副作用未知，且已发现的副作用很大。（相对传统药物和疫苗）
上班时戴N95，4小时换一次，戴护眼罩，穿隔离衣。室内配移动性 hepa filter。
不是阳性的病人只戴2级防护口罩了。
平常逛商店等不戴口罩了。
我儿子要打，他得过奥米克隆，说那些症状比N1H1的症状难受多了，而且持续了好几周。
除了过水， 还能让表面分泌一些粘液（鼻涕）， 觉得更彻底
https://www.amazon.com/Croing-Sinus-Rinse-Kit-Premixed/dp/B076GZHS3M/ref=pd_lpo_3?pd_rd_i=B076GZHS3M&psc=1
如果不会配或无条件配无菌洗鼻液,建议买店里pH balanced配制好的盐袋或液体洗.
https://health.sina.cn/awyh/art/5ef9584b0cf25ef41085f1bc.html
耳朵也可以洗的.