淋巴瘤的亚型很多,确诊有点tricky。Small population of CD10+ T cell是B cell lymphoma的一个特点,但是也可以发生在少量的反应性淋巴结里面。Lambda predominant B cell这个指标确实不大好,如果这个是穿刺活检的话,最好还需要把整个淋巴结切下来做全面病理。如果这个已经是切除的淋巴结的病理,那么lymphoma的可能性确实挺大。 完全理解你现在的心情。但是一定要尽快冷静下来,赶紧行动。即使最终确诊是淋巴瘤也不要太担心。现在淋巴瘤的治疗已经非常成熟规范了,治疗手段非常多。某些亚型的儿童淋巴瘤的预后非常好,治愈率很高。现在赶快找医生,确诊治疗,治疗越早预后越好。Bless!
Pediatric follicular lymphoma (PFL) is a variant of follicular lymphoma (FL) presenting as localized lymphadenopathy in children. Unlike conventional adult FL, PFL typically does not recur or progress. 主要是不知lz孩子的诊断是based on淋巴结 biopsy 还是手术切除标本。看目前报告 现在并没有诊断淋巴癌,等后续分子诊断结果出来吧。
FINAL PATHOLOGIC DIAGNOSIS: Cervical mass, right, excision: 1. Lymph node with atypical lymphoid proliferation (see consultation report) 2. Flow cytometry: a. Lambda predominant B-cell population identified b. Small population of CD10+ T-cells detected 3. Pending B-cell gene rearrangement studies
Specimen: A:Right cervical mass B:Flow Cytometry,Tissue Gross Description: Specimen A, "right cervical mass" is received in formalin and consists of a 2.7 x 2.6 x 1.8 cm tan-pink, ovoid and rubbery tissue mass. The external surface is inked blue. Sectioning shows tan-pink, fleshy and homogenous cut surfaces. Touch preparation is performed. Tissue is collected from the center of the mass and placed in RPMI. Representative sections are submitted in A1-A3. Specimen B tissue sent for flow cytometry. Microscopic Description: A. Right cervical mass: Please see outside consult report. Immunostain performed on block A1: CD20, CD3, CD5, CD21, CD23, BCL6, CD10, BCL2, Ki-67, Cyclin-D1, SOX11, CD30, HSC1&2, CMV(ish) and EBV(sih).
ucsf比stanford好
祝福楼主,孩子康复!
淋巴瘤的亚型很多,确诊有点tricky。Small population of CD10+ T cell是B cell lymphoma的一个特点,但是也可以发生在少量的反应性淋巴结里面。Lambda predominant B cell这个指标确实不大好,如果这个是穿刺活检的话,最好还需要把整个淋巴结切下来做全面病理。如果这个已经是切除的淋巴结的病理,那么lymphoma的可能性确实挺大。
完全理解你现在的心情。但是一定要尽快冷静下来,赶紧行动。即使最终确诊是淋巴瘤也不要太担心。现在淋巴瘤的治疗已经非常成熟规范了,治疗手段非常多。某些亚型的儿童淋巴瘤的预后非常好,治愈率很高。现在赶快找医生,确诊治疗,治疗越早预后越好。Bless!
拍拍,bless 客观的说,做好最最坏打算,lambda predominant,是淋巴瘤概率很大 前面有人说的follicular lymphoma,确实切了就好了,但是在儿童极少见 儿童淋巴瘤基本都是aggressive的 现在儿童血液肿瘤治愈率都很高
小朋友几岁
是这样的.FL好像没怎么见过pediatric case.
为孩子祈祷
atypical lymphoid proliferation 就是无法确认啊
主要是不知lz孩子的诊断是based on淋巴结 biopsy 还是手术切除标本。看目前报告 现在并没有诊断淋巴癌,等后续分子诊断结果出来吧。
MM, 是手术切除标本,不是穿刺结果。谢谢你。 具体就是孩子耳朵后面有个肿块, 年初的时候我看到过一回, 有小指头大小, 不痛不痒也不活动, 因为不懂, 以为没事, 就忘记了, 上个月突然又看到, 已经有鸽子蛋大小了, 赶紧去看医生, 医生说是良性的, 没做活检, 直接手术切除, 切下来再化验就得到了前面的结果。这样说起来耳后肿块从发生到现在已经有一年了, 但是孩子活蹦乱跳没有任何异常, 所以我们一直都没有往肿瘤方面想过。我有一个问题, 如果淋巴瘤发生了 一年孩子还没有任何不适, 最有可能是哪一种淋巴瘤?谢谢
我老公是做lymphoma 研究的,他说小孩的lymphoma 现在治愈率挺高,不用太担心,先确诊再说。 他首推city of hope ,Fred Hutchinson 也不错,但是这两个都在南加。北加的话,他觉得可能Stanford, 或UCSF附属医院
MM能不能麻烦帮我问一下你老公,孩子耳后肿块一年, 无其他任何不适。加上我发在首页的病理报告, 最有可能是哪一种淋巴瘤?对不起我实在太绝望了,抓住一个人就想问,对不起
谢谢你
你孩子多大了,你把病理报告全文私信给我
对不起我是新手发帖, 私信额度已经用完了。 病理报告就是我发在首页的,谢谢你。
Cervical mass, right, excision: 1. Lymph node with atypical lymphoid proliferation (see consultation report) 2. Flow cytometry: a. Lambda predominant B-cell population identified b. Small population of CD10+ T-cells detected 3. Pending B-cell gene rearrangement studies
Specimen: A:Right cervical mass B:Flow Cytometry,Tissue
Gross Description: Specimen A, "right cervical mass" is received in formalin and consists of a 2.7 x 2.6 x 1.8 cm tan-pink, ovoid and rubbery tissue mass. The external surface is inked blue. Sectioning shows tan-pink, fleshy and homogenous cut surfaces. Touch preparation is performed. Tissue is collected from the center of the mass and placed in RPMI. Representative sections are submitted in A1-A3. Specimen B tissue sent for flow cytometry. Microscopic Description: A. Right cervical mass: Please see outside consult report. Immunostain performed on block A1: CD20, CD3, CD5, CD21, CD23, BCL6, CD10, BCL2, Ki-67, Cyclin-D1, SOX11, CD30, HSC1&2, CMV(ish) and EBV(sih).