第三针只能提高抗体数量而非质量?

C
CoolTeeth
楼主 (北美华人网)
http://www.mdlinx.com/news/third-mrna-dose-may-boost-antibody-quantity-but-not-quality/6kFMU0APF29etRp4tIzULz
抗原原罪
Among fully vaccinated people who never had COVID-19, getting a third dose of an mRNA vaccine from Pfizer/BioNTech or Moderna would likely increase levels of antibodies, but not antibodies that are better able to neutralize new virus variants, Rockefeller University researchers reported on bioRxiv ahead of peer review.
They note that in COVID-19 survivors, the immune system's antibodies evolve during the first year, becoming more potent and better able to resist new variants.
In 32 volunteers who never had COVID-19, they found that antibodies induced by mRNA vaccines did evolve between the first and second shots. But five months later, vaccine-induced antibodies were "equivalent" to those seen after the second dose, with "little measurable improvement" in the antibodies' ability to neutralize a broad variety of new variants, said coauthor Michel Nussenzweig.
Therefore, he said, giving those individuals a third dose of the same vaccine would likely result in higher levels of antibodies that remain less effective against variants.
C
CoolTeeth
” a third dose of the same vaccine would likely result in higher levels of antibodies that remain less effective against variants.” 所以现在的关键问题就是第三针是不是the same vaccine,嘿嘿
C
CoolTeeth
这篇文章的另外一个重要发现就是新冠自然感染痊愈的抗体更好,能更好地对付变种。
l
lrwvsxf
lz,谢谢每天及时带来新消息。越来越证实了当初的判断
C
CoolTeeth
回复 4楼lrwvsxf的帖子
不客气。主要是之前看着版上都是片面盲目支持疫苗的帖子觉得应该让大家多了解事情的另一面,这样大家才能做出更明智的选择,而不是一边倒地被主流媒体别有用心的片面报道带歪了方向。
P
Purple_car
回复 1楼CoolTeeth的帖子
今天新闻看到Modena需要第三针booster了
v
vitd120
这篇文章的另外一个重要发现就是新冠自然感染痊愈的抗体更好,能更好地对付变种。
CoolTeeth 发表于 2021-08-04 23:57

最近真是越来越发现自然感染又robust又持久。
在想如果真有抗原原罪和逃逸的话,会影响自然感染更多还是疫苗更多
v
vincentsjtu
http://www.mdlinx.com/news/third-mrna-dose-may-boost-antibody-quantity-but-not-quality/6kFMU0APF29etRp4tIzULz
抗原原罪
Among fully vaccinated people who never had COVID-19, getting a third dose of an mRNA vaccine from Pfizer/BioNTech or Moderna would likely increase levels of antibodies, but not antibodies that are better able to neutralize new virus variants, Rockefeller University researchers reported on bioRxiv ahead of peer review.
They note that in COVID-19 survivors, the immune system's antibodies evolve during the first year, becoming more potent and better able to resist new variants.
In 32 volunteers who never had COVID-19, they found that antibodies induced by mRNA vaccines did evolve between the first and second shots. But five months later, vaccine-induced antibodies were "equivalent" to those seen after the second dose, with "little measurable improvement" in the antibodies' ability to neutralize a broad variety of new variants, said coauthor Michel Nussenzweig.
Therefore, he said, giving those individuals a third dose of the same vaccine would likely result in higher levels of antibodies that remain less effective against variants.
CoolTeeth 发表于 2021-08-04 23:55

那就是频繁打疫苗就可以了,好惨

c
canyousee
回复 4楼lrwvsxf的帖子
不客气。主要是之前看着版上都是片面盲目支持疫苗的帖子觉得应该让大家多了解事情的另一面,这样大家才能做出更明智的选择,而不是一边倒地被主流媒体别有用心的片面报道带歪了方向。
CoolTeeth 发表于 2021-08-05 09:01

对,不知道为什么有些人非要制止别人发信息。 信息发出来交给看信息的人自己判断不知道碍着他们什么事了。
C
CoolTeeth
回复 8楼vincentsjtu的帖子
还必须得打跟原疫苗不一样的才行,否则光有数量没质量对付不了变种,其实大概率就是跟流感疫苗一样了,只是流感每年一针,这个至少每年2针,呵呵
C
CoolTeeth
回复 9楼canyousee的帖子
而且骂我的一点干货都没有只会骂人,我好歹所有的帖子都给了出处也算有理有据。
C
CoolTeeth
回复 6楼Purple_car的帖子
辉瑞早就在喊了,摩德纳晚了一步而已
c
canyousee
回复 9楼canyousee的帖子
而且骂我的一点干货都没有只会骂人,我好歹所有的帖子都给了出处也算有理有据。
CoolTeeth 发表于 2021-08-05 11:56

嗯,如果能给出数据大家一起分享也挺好的,但是他们也给不出任何数据,只会嘲讽,对认清现实一点用处也没有。
凛冬已至
好像第一针反应普遍比较轻,第2针打趴下不少,第3针会怎么样?第4,5,6,7.呢?
C
CoolTeeth
回复 14楼凛冬已至的帖子
My understanding is it will get worse with more shots