https://www.foxnews.com/health/university-pittsburgh-antibody-neutralizes-coronavirus University of Pittsburgh scientists discover antibody that ''neutralizes'' virus that causes coronavirus Scientists at the University of Pittsburgh School of Medicine have isolated the biomolecule The antibody component is 10 times smaller than a full-sized antibody, and has been used to create the drug Ab8, shared in the report published by the researchers in the journal Cell on Monday. The drug is seen as a potential preventative against SARS-CoV-2. According to the report, the drug has been “highly effective in preventing and treating” the SARS-CoV-2 infections in mice and hamsters during tests. The drug also reportedly does not bind to human cells, which suggests it will not have negative side-effects in people. According to the report, the team at University of Texas Medical Branch Center for Biodefense and Emerging Diseases and Galveston National Laboratory tested Ab8 and found it blocked the virus from entering cells. In mice trials, those treated with Ab8 had 10-fold less of the amount of infectious virus compared to those that were untreated.
University of Pittsburgh scientists discover antibody that ''neutralizes'' virus that causes coronavirus Scientists at the University of Pittsburgh School of Medicine have isolated the biomolecule
The antibody component is 10 times smaller than a full-sized antibody, and has been used to create the drug Ab8, shared in the report published by the researchers in the journal Cell on Monday. The drug is seen as a potential preventative against SARS-CoV-2.
According to the report, the drug has been “highly effective in preventing and treating” the SARS-CoV-2 infections in mice and hamsters during tests. The drug also reportedly does not bind to human cells, which suggests it will not have negative side-effects in people.
According to the report, the team at University of Texas Medical Branch Center for Biodefense and Emerging Diseases and Galveston National Laboratory tested Ab8 and found it blocked the virus from entering cells. In mice trials, those treated with Ab8 had 10-fold less of the amount of infectious virus compared to those that were untreated.
不过我听懂行的朋友说,这个药的成本很高,大规模生产将是个问题。
啊?这样啊……
这个还没进入临床实验啊,还早呢。进展最快的是Regeneron,新冠单抗的三期临床都做了两个多月了,这个月底或者下个月初就会揭盲。这很可能是唯一一个疫苗推广之前来得及上市推广使用的单抗药物。
https://investor.regeneron.com/index.php/news-releases/news-release-details/regeneron-announces-start-regn-cov2-phase-3-covid-19-prevention